Matteo Guardamagna

Constellation of studies charts brain development, offers ‘dramatic revision’ The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.

A set of 12 papers published in Nature journals offers new atlases of brain development and hints at the varied evolutionary origins of different cell types.

By Holly Barker

#neuroskyence

www.thetransmitter.org/spectrum/con...

3 Postdoctoral Research Fellows Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.

🚨Job alert🚨

The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour

This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"

euraxess.ec.europa.eu/jobs/383909

Functional specialisation of multisensory temporal integration in the mouse superior colliculus - Nature Communications Whether and how anatomically distinct regions of the superior colliculus (SC) exhibit specialisation in multisensory temporal integration to facilitate different behavioural responses are not fully un...

Proud to have contributed to @gaiabianchini.bsky.social and @flor-iacaruso.bsky.social new paper on how the superior colliculus temporally integrates multisensory information

What did Pasolini know? Fifty years after his brutal murder, the director’s vision of fascism is more urgent than ever With mystery still surrounding Pier Paolo Pasolini’s death, the poet and film-maker’s warnings of corruption and rising totalitarianism offer a chilling message for our times

What did Pasolini know? Fifty years after his brutal murder, the director’s vision of fascism is more urgent than ever

Sensory expectations shape neural population dynamics in motor circuits Nature - Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the...

Thrilled that our paper is out today in Nature!
www.nature.com/articles/s4...

Falling asleep follows a predictable bifurcation dynamic - Nature Neuroscience Li et al. propose a conceptual framework to study the phenomenon of falling asleep based on electroencephalogram data. They show that a tipping point marks the brain’s nonlinear wake-to-sleep transiti...

My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...

A mean-field model of neural networks with PV and SOM interneurons reveals connectivity-based mechanisms of gamma oscillations Classic theoretical models of cortical oscillations are based on the interactions between two populations of excitatory and inhibitory neurons. Nevertheless, experimental studies and network simulatio...

Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo

We are hiring 🎉 Brandeis Neuroscience is looking for an Assistant Professor. The search is in the broad area of cellular/circuit neuroscience. It’s a fantastic place to do research and train students.If you’re interested, apply and reach out with any questions!

academicjobsonline.org/ajo/jobs/30961

Integration of hunger and hormonal state gates infant-directed aggression - Nature Combined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups...

Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice.
www.nature.com/articles/s41...

The astrocytic ensemble acts as a multiday trace to stabilize memory - Nature Emotional experience evokes signalling in astrocytes, which form an ensemble that is reinforced by secondary astrocytic state changes resulting from repeated experience, leading to memory stabilizatio...

𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social

From cognition in the body to the body in cognition Carlos Ribeiro and Albino Oliveira-Maia propose how brain–body interactions may inform the study of ‘higher’ cognitive functions such as learning and memory across model systems.

New essay in @currentbiology.bsky.social special brain-body issue! Fly lab meets psychiatrist: how bodily signals shape cognition and mental health. Great collaboration with Albino Oliveira-Maia showing @champalimaudf.bsky.social discovery ↔️ clinic at its best. www.cell.com/current-biol...

The postsubiculum as a head-direction cortex The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

Great piece and beautiful illustrations!

I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.

doi.org/10.1126/sci...

With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others

Congrats Shaked and the whole team! 🦇

The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.

By @claudia-lopez.bsky.social

#neuroskyence

www.thetransmitter.org/neuroetholog...

High-throughput synaptic connectivity mapping using in vivo two-photon holographic optogenetics and compressive sensing - Nature Neuroscience Using two-photon optogenetics, electrical recordings and sparse signal reconstruction, the authors demonstrate in vivo synaptic connectivity mapping in the mouse visual cortex.

www.nature.com/articles/s41...

Emiliani Lab

New findings solve “developmental biology’s most complicated problem”: how each olfactory neuron in the ant expresses exactly one out of hundreds of olfactory receptors.

By @vcallier.bsky.social

#neuroskyence

www.thetransmitter.org/sensory-perc...

Thanks Juan :) Not yet! But we will have something out soon

For those interested in methods for analyzing a specific frequency of neural activity as a series of discrete events, the CBASS code is posted here with an excellent wiki by @q-perrenoud.bsky.social: github.com/cardin-higle...

Congratulations Juan!!

🚨Big news!🚨
The lab is relocating to Lisbon, joining a great team of experimental and theoretical neuroscientists, and the Neurotechnology Warehouse, a new initiative to bridge basic and translational research.

I'll be sharing postdoc openings soon. Come join us in this new incarnation of the lab!

Stats on #bodybrain #neuroskyence data can become non-trivial pretty quickly: Anything beyond t-tests on 'systole vs diastole' or 'insp vs exp' will include some form of phase binning, so we need adequate surrogates for robust permutation stats. Plus, these are not available for circular data.

A parabrachial hub for need-state control of enduring pain - Nature Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.

Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.

A brief rundown...

www.nature.com/articles/s41...

How does the brain's spatial navigation system develop? I had so many fun discussions with the incredible communities at Johns Hopkins and Columbia this past week - a lot of exciting ideas for experimental and theoretical work ahead.
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com

Come do a postdoc at the Wu Tsai Institute!

WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors.

If you’re interested to work with me, please reach out!

How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions The brain constantly generates predictions based on one’s knowledge of the world, as captured in memory. When these predictions are in error, our knowledge base must be revised to remain relevant. Her...

How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions: Trends in Neurosciences www.cell.com/trends/neuro...

🎉🎉

I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !

With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

We have lost an eminent scientist, Jane Goodall, - do not forget her beautiful work and strong voice: - «hope and action: - value and respect animals and protect them and their habitats»