Karen Lange

I've submitted my abstract!

Abstract submission deadline extended to Monday, February 16, 23:59 hrs CET (no exceptions). Last chance to submit an abstract for inclusion in the programme of #eshg2026 #hybridconference! More information on: 2026.eshg.org/abstracts/

This makes me want to get to the lab and inject some worms!

These strains just arrived from CGC! Very exciting!

The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems Abstract. The Caenorhabditis Genetics Center is launching a new website feature—“Curated Special Collections”—designed to help researchers navigate the eve

The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems

academic.oup.com/genetics/adv...

𝗠𝗲𝗲𝘁 𝗼𝘂𝗿 𝗸𝗲𝘆𝗻𝗼𝘁𝗲 𝘀𝗽𝗲𝗮𝗸𝗲𝗿𝘀 𝗳𝗼𝗿 #𝗖𝗶𝗹𝗶𝗮𝟮𝟬𝟮𝟳!

We are grateful for their participation and look forward to welcoming the cilia community on 8-12, March 2027.

Wishing you all a happy and inspiring 2026! 🎉

#Cilia #Milan

Three people discharged from hospital after chemical spill at Trinity College Dublin Incident took place at Trinity Biomedical Sciences Institute on Tuesday morning

Yikes! Glad everyone is okay. Lab safety is no joke.
www.irishtimes.com/ireland/educ...

You should be able to respond to reviewer comments with memes to liven up the peer review process.

Works great on my computer!

Unfortunately I couldn't get the website to work on my phone. Love the idea of this resource.

Im considering a human genectics conference for next year. Do any C. elegans researchers go to the ASHG or ESHG meetings?

We built this site to allow you to probe our single-nucleus RNA-seq data for adult #Celegans neurons (wt & daf-2 herms, and wt males v herms): cestaan.princeton.edu
and a microPub about how to use it: www.micropublication.org/journals/bio...
We hope the #Celegans community finds it useful! 🧪

Beautiful images like this make me consider working on muscle 😍

New must-read review article for all lovers of #centrioles and #centrosomes 😍👇

#worms #celegans

Removal of the Ciliary Gate Allows Axoneme Extension in the Absence of Retrograde IFT The transition zone (TZ) is a selective barrier that maintains ciliary compartmentalization by controlling protein entry and exit. Cilia assembly requires the crossing of this barrier by intraflagella...

I clicked this link so fast! Right up my alley.

Removal of the Ciliary Gate Allows Axoneme Extension in the Absence of Retrograde IFT

www.biorxiv.org/content/10.1...

Dias Maia Henriques, Dumont, Maton et al. @ijmonod.bsky.social uncover an #anaphase A pathway, driven by the #kinesin-13 KLP-7 and opposed by the kinesin-12 KLP-18, that contributes to chromosome segregation in early #Celegans embryos. rupress.org/jcb/article/...

#Mitosis #CellDivision #Spindle

European C. elegans meeting!

ceneuroeuro2026.sciencesconf.org

Congratulations on your first first-author paper!!!! Good luck tomorrow.

Lovely work by @emiliafil.bsky.social looking at how septins affect cilia in worms

In #GENETICS, @jsrinivasanwpi.bsky.social and the team present a rescue-by-feeding approach, showing that feeding engineered E. coli containing neuropeptides to #Celegans mutants can successfully rescue behavior defects in worms. buff.ly/Qdw9Nsq

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...

Dopaminergic Modulation of Short‐Term Associative Memory in Caenorhabditis elegans Forgetting is a vital, active process that clears irrelevant memories and supports new learning. Using the model organism Caenorhabditis elegans, we investigated how dopamine, a key neurotransmitter,....

🧠 Dopamine and forgetting

A new study shows dopamine helps the brain forget old memories. Worms lacking dopamine held onto memories longer, suggesting forgetting is an active, dopamine-driven process.

🔗 doi.org/10.1111/jnc.70200

#SciComm 🧪 #Neuroscience #Memory

You could start a worm museum with all these gems you keep getting gifted!

Working with C. elegans This channel provides clear demonstrations of core C. elegans lab skills, including: recognizing life stages and common phenotypes, picking and manipulating worms, and maintaining healthy cultures. De...

Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :)
www.youtube.com/@Workingwith...

Huntington's disease successfully treated for first time One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

New cures feel sudden, but the seeds were planted decades ago by basic scientists.

Which seeds will turn into cures? Unpredictable looking forward, a straight line looking back. 🧪🧬 🧵

I'd struggle to find a drive to read this.

C. elegans CED-1 acts in neurons to modulate ciliary protein abundance and extracellular vesicle shedding https://www.biorxiv.org/content/10.1101/2025.09.15.676301v1

Why would anyone want to screen drugs against the model nematode #Celegans?

Check out the latest review in #GENETICS where Peter Roy provides insight and perspective into why scientists choose worms for #drugdiscovery. buff.ly/0Xo54vJ

“‘She uncovered the social experience of women in science’ — the lab assistants who never became managers, the geologists poring over data in government offices while their male peers were doing fieldwork, those who despite their advanced degrees didn’t get hired or promoted, or who were sidelined…”