Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
17.09.2025 17:37 — 👍 98 🔁 39 💬 6 📌 1
Akayama, Shima, Nakamura et al. show that TFEB is regulated by at least two different regulatory mechanisms during lysosomal damage: ATG conjugation system–dependent/independent regulation. rupress.org/jcb/article/...
#Lysosomes #Autophagy
29.08.2025 17:01 — 👍 10 🔁 4 💬 0 📌 0
After CDC shooting, its employees turn their anger to RFK Jr. and Trump
Investigators allege the shooter targeted the agency because of his coronavirus vaccine beliefs, according to two CDC officials briefed on the case.
NEW: The CDC shooting was much worse than initially reported. 181 rounds. 150 windows hit. Staff are furious at RFK Jr. and Trump becuz their long-running fears about anti-vax rhetoric turning deadly seem to be vindicated. @laurenweberhp.bluesky.social + Me.
www.washingtonpost.com/health/2025/...
12.08.2025 11:41 — 👍 1390 🔁 525 💬 24 📌 20
Thank you all for the concern. We are all alive and OK-ish following the targeted attack on the CDC in Atlanta.
09.08.2025 13:27 — 👍 2 🔁 0 💬 0 📌 0
Cocrystal structure reveals the mechanism of FSP1 inhibition by FSEN1 | PNAS
FSP1 is an FAD-dependent oxidoreductase that uses NAD(P)H to regenerate the reduced
forms of lipophilic quinone antioxidants, such as coenzyme Q10 ...
Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanistic insight & a foundation for medchem. Led by Amalia Megarioti & Sitao Zhang. A terrific collaboration with Da Jia.
Brief Skytorial!
1/9
29.05.2025 18:01 — 👍 76 🔁 29 💬 12 📌 2
We've been studying mechanisms of resilience that protect lysosomes from damage and wrote a review on the topic. We consider lysosomal stress and damage on a spectrum. Please help me share as this is my first post 😀 and I don't have many followers! 🙏 Open Access: www.embopress.org/doi/full/10....
27.02.2025 15:54 — 👍 61 🔁 43 💬 0 📌 4
Atlanta Stand Up For Science March poster, State Capital, Liberty Plaza, March 7, 2025 noon-4
Stand Up For Science next Friday (3/7)! In 2024, Georgia institutions received just over $1 billion in funding and had more than $30 billion in economic impact in GA. That's a PHENOMENAL return for tax payers- let's share that news!
27.02.2025 01:36 — 👍 13 🔁 7 💬 1 📌 2
Supplements: too good to be true?
The dietary supplement industry in the United States is estimated to be worth $70 billion or more. The supplement market grew by 50% from 2018 to 2020. It is estimated that 100,000 unique supplements are currently available for purchase.
The FDA requires the following disclosure be displayed on the package of all supplements: "These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, or cure, or prevent any disease." Be skeptical of any supplement that is marketed with claims contrary to that disclosure. Always consult with your primary care provider before starting or stopping any supplement regimen.
If it seems too good to be true, it probably is.
Harvard Health reports on the recent ruling that the makers of Prevagen can no longer claim their #supplement improves #memory. The author recommends being wary about supplement marketing claims, which are often false, misleading, or based on insufficient research.
20.02.2025 21:00 — 👍 1 🔁 1 💬 0 📌 0
YouTube video by Association of American Universities
Facilities and Administrative (F&A) Costs Explainer
Make sure you, your trainees, and anyone else who might listen to you understands what "indirects" actually are, how they are established, and what Universities contribute. H/T @rodallab.bsky.social
Please share widely!
www.youtube.com/watch?v=yxTD...
11.02.2025 15:00 — 👍 151 🔁 115 💬 6 📌 9
Started off this morning emailing my Senators and Congressman about the NIH and the potential damage being done by unnecessary disruptions.
They need to hear from us loud and clear. Constituents matter to them as one of the primary purposes of a politician is to get re-elected (and its their job).
23.01.2025 11:26 — 👍 314 🔁 130 💬 11 📌 11
Excited to share the lab's recent publication. Granulins are critical for lysosome function and brain health to prevent neurodegeneration. Our data suggest that granulin peptides could be used to treat frontotemporal dementia (FTD), Parkinson’s disease, Alzheimer’s disease.
t.co/pN28kabjIA
21.11.2024 20:48 — 👍 18 🔁 3 💬 0 📌 1
Great work from Mark Sands’ lab showing a 50% reduction in lysosomal enzymes puts you at risk for Alzheimer’s and other neurodegenerative diseases.
18.11.2024 23:34 — 👍 15 🔁 2 💬 0 📌 0
Assistant Professor @OhioState in a toxic relationship with lysosomes. ECR Editor @MBoCjournal. Former @NIH. Views are my own. http://bonetponcelab.com/
I'm a Physicist and R&D Engineer. Fascinated by optimal designs, I seek to improve and invent technologies.
Homepage: amsikking.github.io
Postdoctoral Researcher | Neurodegeneration, Lysosomes & FTD | Rosa Rademakers Lab, VIB-UAntwerp Center for Molecular Neurology
theoretical physical chemist, molecular modeller and chem- and bioinformatician - #AlphaFoldology enthusiast
Palacky University Olomouc, ORCID:0000-0001-9472-2589 #boardgamegeek (tweets my own) #ELIXIRCZ
The #1 ranked open-access neuroscience peer-reviewed journal with a 2024 Impact Factor (IF) of 17.5 and a five-year IF of 19.3. Official journal of BrightFocus Foundation
Est. 1929, JAX is a non-profit scientific research institute specializing in genetics, genomics & mouse models of disease.
USA, Japan, China: https://www.jax.org/
Hospital Operations and Strategy Consultant.
Husband. Ultraendurance athlete. World traveler. Pianist. Dog owner.
My voice represents only me, and not any institution with which I may have been affiliated.
https://youtube.com/@TEugeneDayDSc
Physicist Turned Psychologist | Senior Researcher in #STEMed | Meta-Analysis Nerd | https://d-miller.github.io/
Also posts about 🧪 science funding to focus my attention.
Personal account. I don’t speak for my employer or any other orgs.
This isn’t who it would be if it wasn’t who it is. You gotta go down if you want to get up.
This is the Bluesky Edition of Chop. The OG Chop is still here - https://bsky.app/profile/chopaganda.shakedown.social.ap.brid.gy
Asst. Prof of Biochem. & Mol. Bio. at Michigan State.
Previously at Harvard, NCI, UCSF, and Macalester | aging | cancer | chembio | metabolism | enzymology | RNA modifications | mass spec | STEMEd | runner | boardgamer | my views
Stem Cell Biologist and Neuroscientist, using #stemcells and #organoids to model neurodegeneration.
Indiana University School of Medicine
Stark Neurosciences Research Institute
Your Jeopardy! pal. Author of 100 PLACES TO SEE AFTER YOU DIE (bit.ly/3kLgJKO) and a bunch of other stuff. OMNIBUS co-founder (patreon.com/omnibusproject).
The fastest growing independent news network in the world. We cover breaking news, politics, law and more. We are unapologetically pro-democracy.
Official Account for the Office of California Governor Gavin Newsom.
Building a #CaliforniaForAll.
🔗 linktr.ee/CAgovernor
Husband and father. 40th Governor of California. Former Lt. Governor of California. Former San Francisco Mayor. Personal account.
Mostly music, but also sports. Also a decent bit of book talk, outdoorsy stuff, etc. Not FJM.
My teams: Falcons, Hawks, Blue Jays, Atlanta United, PAOK, Alabama, UAB
Theoretical Astro/Physicist:
https://chanda.science
First book:
https://tinyurl.com/DisorderedCosmos
PREORDER MY NEXT BOOK:
https://tinyurl.com/EdgeOfSpaceTime
Newsletter:
news.chanda.science
all Black/all Jewish. 🏳️🌈/agender/woman.
Posts by/for me🖖🏽
Science and music writer. EIC of @kellogginsight.bsky.social.
Frontier models for all molecules of life.
