Josiah

Leader in smallpox eradication, Dr. William Foege, dies at 89 Dr. William Foege, a leader of one of humanity's greatest public health victories — the global eradication of smallpox — has died.

Dr. William Foege, a leader of one of humanity's greatest public health victories — the global eradication of smallpox — has died.
https://to.pbs.org/49WGkpV

Bringing African ancestry into cellular neuroscience Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.

Very important research to establish African ancestry cell lines! #Neuroskyence www.thetransmitter.org/cellular-neu...

I cannot tell you how absolutely infuriatingly this stuff comes across to Europeans.

When we say America is no longer a reliable ally, it goes considerably deeper than Donald Trump himself. This kind of complacent, condescending shit is a *huge* part of it.

This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024–25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.

This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.

www.nature.com/immersive/d4...

What?

🇦🇷 Sources: Atlanta United advancing on deal to acquire left back Elias Baez from San Lorenzo.

Not totally done but close and expected to get over the line.

Fee will be $3m. Final details now. Will be U-22 initiative signing.

I'm going to be very blunt here: headlines like this and articles like this are a significant part of our media problem because they make people believe things that aren't true

The way the press is treating chatbots, like they have agency and they “know” things all of a sudden, crossed the line recently from dumb and obsequious to something else entirely. Treating them as alive and making conscious decisions is an almost religious belief. It won’t age well.

CBS News is finished

me dressed up and exercising at the airport before my 8 hour flight

As called by Nolan Alexander on Kennesaw State radio:

N908DA 7 points 57 minutes ago So since GTA 5: Kennesaw State started a football program Moved up to FBS Won a conference championship All before GTA 6

Why is Bryce Harper putting his life in the hands of a guy with a degree in Dungeons and Dragons bro

Jesus Christ

It's that time of year when Americans set up quaint, walkable Christmas villages in their living rooms, dreaming of living in such a cozy place.

​Meanwhile, they'll show up to city council meetings to fiercely oppose any plan that would actually build that kind of car-lite community in real life.

Prof. Laura Dassama (Stanford Chem) is developing a small-molecule therapy for sickle cell disease that removes BCL11A, restoring fetal hemoglobin without gene editing. Her goal is a simpler, more affordable sickle cell therapy. brnw.ch/21wXP8k

Human genetics of steatotic liver disease: insights into insulin resistance and lipid metabolism - Nature Metabolism This Review summarizes our current knowledge about the genetic underpinnings of metabolic-dysfunction-associated steatotic liver disease and highlights its causal association with type 2 diabetes and insulin resistance.

REVIEW | R Mancina, L Valenti, @stefano-romeo.bsky.social (U Rome, U Milan, U Gothenburg):

The genetic underpinnings of MASLD and causal associations with T2D and insulin resistance. 🧪

New Gene-Editing Strategy Could Help Development of Treatments for Rare Diseases

This new gene editing strategy ignores nonsense mutations that produce a truncated protein instead of "repairing" the gene. This allows more patients to be treated.

There is some hope cystic fibrosis & Duchenne muscular dystrophy. This study was #NIH funded.

🧪🎁🔗 www.nytimes.com/2025/11/19/h...

+ every $1 invested in NIH research returns ~$1.47 to the economy

Every $1 invested in women’s health returns $3! to the economy.

It’s clear who is not valued in this society.

An uptick in peanut allergies in children around the turn of the century prompted parents to avoid peanut exposure. But updated research showed that early introduction is both safe and effective at reducing allergies.

🎙️ @drdavidhill.bsky.social

🎧 podcast.publichealth.jhu.edu/980-why-earl...

🎯 CTCA: Enlarged right atrium and ventricle with a wide secundum ASD. Coronaries show multifocal calcification and the aortic root is dilated.

🎯 Secundum ASD is the commonest interatrial septal defect, located at the fossa ovalis.

👤 Craig Hacking, radiopaedia.org/cases/206028

A new theory helps explain blood clots complications in COVID-19

G. Gregory Neely & team discover P-selectin, expressed on the surface of activated platelets, suppresses SARS-CoV-2 infection in mice and promotes interaction between SARS-CoV-2 and the endothelial cells: www.jci.org/articles/vie...

this is what ten years of obsession with "wokeness" in the media was trying to get to btw bsky.app/profile/mari...

An education in tolerance: the 2025 Nobel Prize in Physiology or Medicine

journals.biologists.com/dmm/article/...

But I don't disagree with any of those names

Well, at least you haven't made my point for me.

I think the excellent ball he played in for the assist to Tessman really spoke for itself on that front

ship of FOOLS

HAITI ARE GOING TO THE WORLD CUP FOR THE FIRST TIME SINCE 1974

C'EST BONNNNNNNN

Certain man aren't gonna like this but the biggest winner of this #USMNT window is absolutely Gio Reyna