Matthias Krause's Avatar

Matthias Krause

@matthias-krause.bsky.social

Cell migration and endocytosis research lab https://cytoskeleton.wixsite.com/krauselab

241 Followers  |  342 Following  |  19 Posts  |  Joined: 08.11.2024  |  1.862

Latest posts by matthias-krause.bsky.social on Bluesky

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Cell Migration Seminars Cell Migration Seminars every Tuesday at 16:00 BST.

If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...

29.09.2025 01:48 โ€” ๐Ÿ‘ 43    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Bioimage Analysis Specialist | King's College London

BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...

29.09.2025 09:48 โ€” ๐Ÿ‘ 60    ๐Ÿ” 80    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Next, at #EYSF2025 @reviewcommons.org is presented by @saramonaco-rc.bsky.social. Itโ€™s journal-agnostic, concentrates on science only and can save time as the peer-reviewed preprints can easily be resubmitted. How great would it be if we could ditch publishing and switch to reviewed preprints?

24.09.2025 11:43 โ€” ๐Ÿ‘ 2    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Iโ€™m not sure as a community we **truely** acknowledged how powerful the #CellMigrationSeminarSeries series was at keeping us connected at such an uncertain time. Thank-you @ankita13jha.bsky.social @adamshellard.bsky.social @drjenmitchell.bsky.social & @simplythebex.bsky.social

29.09.2025 02:07 โ€” ๐Ÿ‘ 19    ๐Ÿ” 10    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N

17.09.2025 17:20 โ€” ๐Ÿ‘ 60    ๐Ÿ” 26    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 4
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Postdoctoral Research Associate: Modelling Neural Crest Anomalies (mouse/human) - the Node The Liu lab is looking for a postdoc with a love of embryos and developmental biology! This post is part of an MRC-funded collaboration between Karen Liuโ€™s lab at Kingโ€™s College London and Marco Trizz...

Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social

thenode.biologists.com/jobs/postdoc...

05.08.2025 10:15 โ€” ๐Ÿ‘ 39    ๐Ÿ” 43    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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๐ŸŽ“ My team is seeking a PhD student in Biochemistry & Cell Biology at I2BC, Paris-Saclay!
๐Ÿ”ฌ Study cytoskeletal signaling in collective cell migration
๐ŸŒ Fully funded, 3 yrs | ๐Ÿ“ Gif-sur-Yvette, France
๐Ÿ—“๏ธ Apply by Aug 22 via the following link:
emploi.cnrs.fr/Offres/Docto...

06.08.2025 19:10 โ€” ๐Ÿ‘ 12    ๐Ÿ” 15    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Drosophila as a model system to understand #collagen IV-related genetic disease. Learn how fly genetics and exploding brain tissue can inform on #ECM defects and pathological mechanisms. Team effort led by a very talented recent PhD graduate, Angus Nichols. doi.org/10.1016/j.ma...

28.07.2025 09:30 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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In new @jcb.org study from Muziyue Wu et al. @oweinerlab.bsky.social, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions. rupress.org/jcb/article/...

#Cytoskeleton #Actin #Migration #Motility #Biophysics

16.07.2025 18:45 โ€” ๐Ÿ‘ 10    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Congratulations, Jez!!

17.07.2025 06:16 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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I am so proud of @jezcarlton.bsky.social . What a magnificent inaugural lecture, many congratulations Professor Carlton!

16.07.2025 22:14 โ€” ๐Ÿ‘ 94    ๐Ÿ” 6    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.

OMG, this is such a cool paper from Patrick Caswell's lab. They express Rab25-mCherry-GFP-nanobody in cells, microinject GFP-magnetic particles, then use a magnet to pull Rab25 to the plasma membrane to show that it can trigger actin protrusions! I want this system.
www.science.org/doi/10.1126/...

08.07.2025 21:20 โ€” ๐Ÿ‘ 62    ๐Ÿ” 17    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
Nance-Horan Syndrome-like 1 interacts with endophilin and Ena/VASP proteins to promote fast endophilin-mediated endocytosis Endocytosis is crucial for various physiological processes, facilitating the uptake of membrane proteins and extracellular material. Fast endophilin-mediated endocytosis (FEME), driven by endophilin A (EndoA), enables clathrin-independent, ligand-induced receptor uptake at the leading edge of cells. Whilst F-actin polymerisation is essential for FEME, how actin dynamics are regulated at sites of FEME is unknown. NHSL1, a member of the Nance-Horan Syndrome protein family, localises to the leading edge of cells, where it regulates migration, and to vesicular puncta, where its function is undetermined. Here, we show that NHSL1 and its uncharacterised family member NHSL2 co-localise and engage in direct, multivalent interactions with EndoA. NHSL1 also binds Ena/VASP proteins, a family of actin elongators. NHSL1 promotes FEME in cells and its interactions with EndoA and Ena/VASP proteins are required for this function. Thus, NHSL1 may cooperate with EndoA and Ena/VASP proteins to control membrane invagination and actin polymerisation, thereby mediating FEME. ### Competing Interest Statement The authors have declared no competing interest.

Manuscript from our lab on BioRxiv: We provide mechanistic insights that NHSL1 promotes Fast endophilin mediated carrier formation via both endophilin and Ena/VASP proteins thereby may facilitate membrane bending and Ena/VASP mediated actin polymerisation. www.biorxiv.org/content/10.1...

08.07.2025 10:19 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Postdoctoral Fellowships The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.

Interested in applying for a Marie Skล‚odowska-Curie Postdoc Fellowship? Contact me for exciting postdoc projects in neural crest or cancer cell migration, endocytosis, advanced imaging at Kingโ€™s College London. Matthias.Krause@kcl.ac.uk
marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

04.07.2025 09:16 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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NHSL3 interacts with Ena/VASP proteins and the Scar/WAVE complex and promotes cell migration Tight control of mesenchymal cell migration is important for embryonic development and its deregulation causes disease. It is driven by lamellipodia protrusion, the leading edge of the migrating cell....

New from our lab: We identify NHSL3 as a lamellipodial Ena/VASP and Scar/WAVE complex interacting protein binding the latter with a unique mode of interaction and inhibiting Arp2/3 complex activity but unexpectantly promoting mesenchymal cell migration efficiency. www.biorxiv.org/content/10.1...

02.07.2025 15:24 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Mechanobiology across the tree of life

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date ๐Ÿ—“๏ธ. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...

20.11.2024 16:49 โ€” ๐Ÿ‘ 173    ๐Ÿ” 76    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 4
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๐Ÿšจ Registration Now Open! ๐Ÿšจ

Join us for the 2025 Triangle Cytoskeleton Meeting on Sept. 15 at Trent Semans Center!

Speakers:
๐Ÿ”ฌ Dr. Kris DeMali
๐Ÿงซ Dr. Rae Cho
๐Ÿงฌ Dr. Stefanie Redemann

Showcase your research, exchange ideas, and connect with the Cytoskeleton community!

Register now! ๐Ÿ’ป

#TCM2025

08.07.2025 03:38 โ€” ๐Ÿ‘ 3    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Intracellular mechanics and organelle mechanobiology Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to meโ€ฆ

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! ๐Ÿ™ #EMBOmechanobio

meetings.embo.org/event/26-org...

04.07.2025 15:50 โ€” ๐Ÿ‘ 71    ๐Ÿ” 44    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
Postdoctoral Fellowships The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.

Interested in applying for a Marie Skล‚odowska-Curie Postdoc Fellowship? Contact me for exciting postdoc projects in neural crest or cancer cell migration, endocytosis, advanced imaging at Kingโ€™s College London. Matthias.Krause@kcl.ac.uk
marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

04.07.2025 09:16 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

New manuscript from our lab: Fast Endophilin Mediated Endocytosis (FEME), facilitates ligand induced endocytosis of a variety of receptors at the leading edge of migrating cells. The mechanism behind how FEME priming patches form is emerging.

05.12.2024 18:42 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Another new manuscript from our lab and excellent collaboration with the Bear lab @coronin.bsky.social: The Scar/WAVE complex promotes mesenchymal cell migration through Arp2/3 mediated lamellipodia protrusion.

17.03.2025 18:43 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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NHSL3 interacts with Ena/VASP proteins and the Scar/WAVE complex and promotes cell migration Tight control of mesenchymal cell migration is important for embryonic development and its deregulation causes disease. It is driven by lamellipodia protrusion, the leading edge of the migrating cell....

New from our lab: We identify NHSL3 as a lamellipodial Ena/VASP and Scar/WAVE complex interacting protein binding the latter with a unique mode of interaction and inhibiting Arp2/3 complex activity but unexpectantly promoting mesenchymal cell migration efficiency. www.biorxiv.org/content/10.1...

02.07.2025 15:24 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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All three kids degreed up & off for gainful employment now...

01.07.2025 10:55 โ€” ๐Ÿ‘ 23    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).

01.07.2025 04:46 โ€” ๐Ÿ‘ 58    ๐Ÿ” 49    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 1

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

23.06.2025 14:29 โ€” ๐Ÿ‘ 67    ๐Ÿ” 87    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 7
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Doctoral (PhD) student position available - epithelial-immune cell interactions in Drosophila wounding

18.06.2025 14:15 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
HOME | londoncellmotility

This Friday, UK Cell Motility Club symposium in Cambridge, UK: exciting PhD student and Postdoc speaker line up! A few last minute spots available. Follow us on @uk-cmc.bsky.social
cytoskeleton.wixsite.com/londoncellmo...

10.06.2025 10:56 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ‘‹ Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab!
๐Ÿ‘‰ deadline 20/06
๐Ÿ‘‡ check it out

www.godinholab.com

03.06.2025 08:57 โ€” ๐Ÿ‘ 38    ๐Ÿ” 43    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Very excited to share the first preprint from the lab:
www.biorxiv.org/cgi/content/...
We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations.
Want to know of they cope with feeling squeezed? ๐ŸŸ๐Ÿ ๐ŸŸ

06.06.2025 21:44 โ€” ๐Ÿ‘ 64    ๐Ÿ” 14    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
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#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?

30.05.2025 20:23 โ€” ๐Ÿ‘ 36    ๐Ÿ” 26    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2

@matthias-krause is following 20 prominent accounts