Matthias Krause

Drosophila as a model system to understand #collagen IV-related genetic disease. Learn how fly genetics and exploding brain tissue can inform on #ECM defects and pathological mechanisms. Team effort led by a very talented recent PhD graduate, Angus Nichols. doi.org/10.1016/j.ma...

In new @jcb.org study from Muziyue Wu et al. @oweinerlab.bsky.social, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions. rupress.org/jcb/article/...

#Cytoskeleton #Actin #Migration #Motility #Biophysics

Congratulations, Jez!!

I am so proud of @jezcarlton.bsky.social . What a magnificent inaugural lecture, many congratulations Professor Carlton!

Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.

OMG, this is such a cool paper from Patrick Caswell's lab. They express Rab25-mCherry-GFP-nanobody in cells, microinject GFP-magnetic particles, then use a magnet to pull Rab25 to the plasma membrane to show that it can trigger actin protrusions! I want this system.
www.science.org/doi/10.1126/...

Manuscript from our lab on BioRxiv: We provide mechanistic insights that NHSL1 promotes Fast endophilin mediated carrier formation via both endophilin and Ena/VASP proteins thereby may facilitate membrane bending and Ena/VASP mediated actin polymerisation. www.biorxiv.org/content/10.1...

Interested in applying for a Marie Skłodowska-Curie Postdoc Fellowship? Contact me for exciting postdoc projects in neural crest or cancer cell migration, endocytosis, advanced imaging at King’s College London. Matthias.Krause@kcl.ac.uk
marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

NHSL3 interacts with Ena/VASP proteins and the Scar/WAVE complex and promotes cell migration Tight control of mesenchymal cell migration is important for embryonic development and its deregulation causes disease. It is driven by lamellipodia protrusion, the leading edge of the migrating cell....

New from our lab: We identify NHSL3 as a lamellipodial Ena/VASP and Scar/WAVE complex interacting protein binding the latter with a unique mode of interaction and inhibiting Arp2/3 complex activity but unexpectantly promoting mesenchymal cell migration efficiency. www.biorxiv.org/content/10.1...

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...

🚨 Registration Now Open! 🚨

Join us for the 2025 Triangle Cytoskeleton Meeting on Sept. 15 at Trent Semans Center!

Speakers:
🔬 Dr. Kris DeMali
🧫 Dr. Rae Cho
🧬 Dr. Stefanie Redemann

Showcase your research, exchange ideas, and connect with the Cytoskeleton community!

Register now! 💻

#TCM2025

Intracellular mechanics and organelle mechanobiology Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio

meetings.embo.org/event/26-org...

Interested in applying for a Marie Skłodowska-Curie Postdoc Fellowship? Contact me for exciting postdoc projects in neural crest or cancer cell migration, endocytosis, advanced imaging at King’s College London. Matthias.Krause@kcl.ac.uk
marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

New manuscript from our lab: Fast Endophilin Mediated Endocytosis (FEME), facilitates ligand induced endocytosis of a variety of receptors at the leading edge of migrating cells. The mechanism behind how FEME priming patches form is emerging.

Another new manuscript from our lab and excellent collaboration with the Bear lab @coronin.bsky.social: The Scar/WAVE complex promotes mesenchymal cell migration through Arp2/3 mediated lamellipodia protrusion.

NHSL3 interacts with Ena/VASP proteins and the Scar/WAVE complex and promotes cell migration Tight control of mesenchymal cell migration is important for embryonic development and its deregulation causes disease. It is driven by lamellipodia protrusion, the leading edge of the migrating cell....

New from our lab: We identify NHSL3 as a lamellipodial Ena/VASP and Scar/WAVE complex interacting protein binding the latter with a unique mode of interaction and inhibiting Arp2/3 complex activity but unexpectantly promoting mesenchymal cell migration efficiency. www.biorxiv.org/content/10.1...

All three kids degreed up & off for gainful employment now...

- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

Doctoral (PhD) student position available - epithelial-immune cell interactions in Drosophila wounding

This Friday, UK Cell Motility Club symposium in Cambridge, UK: exciting PhD student and Postdoc speaker line up! A few last minute spots available. Follow us on @uk-cmc.bsky.social
cytoskeleton.wixsite.com/londoncellmo...

👋 Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab!
👉 deadline 20/06
👇 check it out

www.godinholab.com

Very excited to share the first preprint from the lab:
www.biorxiv.org/cgi/content/...
We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations.
Want to know of they cope with feeling squeezed? 🐟🐠🐟

#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?

Flyer of the international meeting of the German society for Cell Biology in Heidelberg Oct 26-29 with all topics and speakers listed.

50 Years of Cell Biology: German Society for Cell Biology Meeting, October 26 – 29, 2025 | Heidelberg, Germany
Early bird registration deadline: June 15, 2025

Cyril Andrieu, Bren Hunyi Lee & Anna Franz find that cell deformations generated by stochastic actomyosin waves drive random-walk swimming migration in Drosophila adipocytes.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess

It is so much easier to find papers on sci-hub than using 2-F*cktor authentication and VPN - thank you Alexandra Elbakyan
sci-hub.se/alexandra

Happy to share details of this meeting and the exciting line-up of speakers. Hope to see you there. Please re-post www.crick.ac.uk/whats-on/5th...

I cannot wait for this meeting, it's going to be awesome

A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”

Choose Science. Choose Europe.

A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.

With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.

Apply by 10 September → europa.eu/!fBTMgF

And it ends today!