Andreas Aufschnaiter

WHERE ARE ALL THE DARK PROTEINS? There are thousands of unconventional open reading frames (ORF) - stretches of code with specific three-letter-sequences - in the human genome that aren't expected to produce a protein, but seem to do so anyway. They can be upstream or downstream of a conventional gene, or they can overlap with it to varying degrees. Many are found within long non-coding RNAs, which weren't thought to encode proteins. Some of these peptides seem to regulate the activity of nearby genes, but for most, their purpose is unclear.

#Medsky🧪#microsky #immunosky Finding the “dark proteins” .There are thousands of unconventional open reading frames (ORF) - stretches of code with specific three-letter-sequences - in the human genome that aren't expected to produce a protein, but seem to do so anyway.

07.02.2025 03:41 — 👍 23    🔁 1    💬 3    📌 1

20.01.2025 09:51 — 👍 2    🔁 2    💬 0    📌 0

Mitochondria and cell death - Nature Cell Biology Several processes of regulated cell death engage or use mitochondria, which are thus central hubs that not only coordinate cell death but also elicit non-lethal signalling mediated by mitochondrial ou...

☕This year, in our #CellDeath focus:
Glover, Schreiner, Dewson & Tait reviewed the intersection of #mitochondria and cell death. #pyroptosis #ferroptosis #necroptosis #apoptosis
👉https://rdcu.be/d46gt
www.nature.com/articles/s41...

28.12.2024 20:29 — 👍 55    🔁 19    💬 1    📌 2

hello fellow whovian

21.12.2024 18:51 — 👍 1    🔁 0    💬 0    📌 0

agarose gel with a happy face

sadistic smile only to mock me before I found out the PCR didn't work 😂.. #scienceisfun

21.12.2024 16:32 — 👍 13    🔁 0    💬 2    📌 0