Nelson Lau Lab

@baym.lol Age of Phage is now done. Plasmid time, bitches! They have won!

The moose out front should have told you… grants.nih.gov/grants/guide...

PO's warned R01 renewal odds abysmal, better luck trying to convert R01 to R35 MIRA asap. After trying both approaches, competing renewal definitely DOA, zero empathy for pandemic impact, while MIRA still a crapshoot, reviewers wanted R01 despite MIRA instructions. And now shutdown! FML!

Dude's shirt reads "Back on my Bull Shit"!

This guy's shirt I saw walking to work sums up today's Oval office Dunning Kruger-esque press briefing on ASD.

Thanks! Will send you an email after I'm done with my fall teaching!

Thanks! Is there an infectious clone of PCLV?

We study how the mosquito Piwi pathway molecularly interacts with arboviruses and bunyaviruses. But we don't yet know how to manipulate these viruses as infectious clones. Do you have tips on this?

Characterization of the piRNA Complex from Rat Testes Small noncoding RNAs regulate processes essential for cell growth and development, including mRNA degradation, translational repression, and transcriptional gene silencing (TGS). During a search for c...

And the piRNA citations on your page mirgenedb.org/information only cite Tuschl, Hannon, Lin lab papers, but left out mine published at same time: pubmed.ncbi.nlm.nih.gov/16778019/ . I would appreciate if you could add our paper: www.science.org/doi/10.1126/...

I finally took a good look at mirgenedb.org/information. Very useful! I will do more to compare it against miRBase, since they did not reject the bad miR-548. Have you tried to get more consistency between miRBase and mirgenedb?

What is your impression of the hsa-mir-548xxx family of microRNAs? MITEs foldback masquerading as a "miRNA"? We've seen an instance where total mRNA across the mir-548-y locus go way up, but zero increase in mature mir-548-y or any other mir-548-xxx member.

WHY? Just why? Those cards are disturbing on so many levels, and lacking representation of plant biologists like how Nobels passed over Baulcombe and Benning. It was Benning who first coined the name Argonaute for these genes.

MAJOR FOMO!

License plate EMINEM!

Real Slim Shady in Boston?

license plate: BSMART

license plate: NASTY

license plate: CLASSY

BSMART, NASTY, or CLASSY? A skeet game I play with @lucksmith.bsky.social

Is this halt of just new not yet NOGA's, or does the halt also apply to all Non-Competing ongoing grants in FY25/FY26?

Take care and hope all that caloric restriction helps you live longer!

Case in point, HHMI? No offense to @harmitmalik.bsky.social, you are one of the most vocal advocates here! But what is your insider insight into your HHMI colleagues and the HHMI brass? Can they throw out just some lifejackets to those barely treading water?

Nuns of your business?

Was that rocket around LA California? I also when to elementary school in Lawndale with one of those, was dared to jump from top level, some how my kid legs did not break.

i always douse sashimi with plenty of wasabi. the alkylating condiment has antimicrobial effects along with adding flavor.

That is some nice luciferase activity!

That interchange is always backed up with stopped traffic, so he might be okay....

Did you get bit? If so, you may have received an innoculation of mosquito-specific viruses she was carrying.

I see you have a 2021 Science Advances paper. Was this drama more recent? Now I'm nervous of my paper that is maybe under review at Sci Adv? It's been 3 weeks and tomorrow is Friday!😟

Newark?

Phew! Main power is back! What happened out there?

Welp! Sitting in dark office, entire lab building on emergency power since 3pm. Whole chunk of downtown Boston without power!

Michael, so sorry! You have alot of fans of your research, myself included. Keep fighting and thank you for this brave post! Hope HMS backs up you and your lab to fight another day!

Does EviAnn do any annotation of repeats? There is also room for improvement with the existing repeat annotation tools.

Happy Dog Day, Chester the Tennis Pug!