Jeroen

Rogue DNA rings reveal earliest clues to deadly brain cancer’s growth In a new study, published today in Cancer Discovery, the eDyNAmiC team, led by Paul Mischel at Stanford University, and collaborator Charlie Swanton at the Crick, integrated genomic and imaging data f...

Research from the Cancer Grand Challenges eDNyamiC team found that rogue rings of DNA appear early in glioblastoma, a very aggressive form of brain cancer.

Co-first author Imran Noorani explains how this work makes the case for early detection of these tumours.

www.crick.ac.uk/news/2025-09...

The people have spoken!

@romanmars.bsky.social please do the Brannock device episode! Shoe sizes are so weird in general, and the Brannock is an amazing thing. It’d be brilliant to hear your take on it

Me: this is great, glad to see authors ripped off by AI getting their due.

Me after using the search tool: I am one of these ripped off authors.

Academics, it only takes a minute. Seven of my papers are in this and I had no idea.

Article on BBC news. Title: AI designs antibiotics for gonorrhoea and MRSA superbugs Description: Two new potential drugs have been designed by AI to kill drug-resistant bacteria, in a major Massachusetts Institute of Technology study.

I really dislike how science has started calling almost any fancy computational technique AI. 🧪

The framing of this entire article makes it sound like a benevolent AI independently made these drugs.

That is *pure fantasy*.

Instead: a team of scientists made a machine learning model for a study.

Fun! I think it's subtle but informative. Thanks for trying it out! What is the rank based on btw, last year's table? (ie are we second)

Saturation gradient could work too if you want to include colour, but I rather like the monochromatic vibe you have going currently. And yeah, a key would help!

Interesting! Would it make sense to have an opacity gradient based on season (17/18 most transparent, 24/25 least) so you have a way to track progress over time? Currently the datapoints are interesting but it's difficult to tell if there are patterns/developments over time.

Quiet-ish: Attack helicopter been circling us here in Rotterdam. Rude.

Watch out for godzilla kinases!

Happy birthday! B is learning to ride a cargo bike. She is *not* convinced, but being very brave about it.

Yeah it’s wild. Also, some youtuber apparently came recently and ate TWENTY THREE pancakes. I can’t process that in my little mind

Ok yeah so this is grand actually. Unlimited pancakes. Seeing the city from the river. Ball pit even. Recommend it.

Big excited

What! The pancakes are unlimited. I am 100% doing this today. The toddler is going to go full augustus gloop on the syrup. Can’t wait.

As a case in point, i just spent 20 mins looking for the alien chestburster i once stuck farage’s face on. Spent a full day making it as a motion tracking exercise. Lost to the winds of time.

So excited for this course - the first two episodes are already so so good at going into one of my main stumbling blocks with watching Unreal tuts: not really getting how Unreal expects me to *think*, and my Houdini mindset just wasn't porting across properly. Great work, @chriskopic.bsky.social!

didn't dare calling our sheep weak though

Well i can’t *not* throw Belka in the mix now can I

You can always just claim Guy has the same etymology as Gijs(brecht) in Dutch. “Radiant and noble”. In an ill-dressed and ridiculous kind of way

Poster showing a kinase domain emerging from Lake Wakatipu, with a list of speakers

Exciting to open registration for the IUBMB Focussed Meeting on Emerging roles of (pseudo)kinases! Fantastic speakers in an unmatched location, lots of speaking slots available for ECRS.
Interested in kinases or pseudokinases? We would love to see you in Queenstown!

www.ivvy.com.au/event/IUBMB2...

Fair point! They are big and cumbersome beasts.. Just trying to troubleshoot whether the issue is with the pcie port or the card: Any other free ports you can pop it into?

Eugh that sucks, sorry.. Out of curiosity: if you stick your gpu into that pcie slot, is it recognised?

From the buildapc community on Reddit Explore this post and more from the buildapc community

(Looked it up: this was to fix setups with pcie 4.0 mobo and pcie 4.0 gpu connected through a pcie 3.0 riser cable. See eg www.reddit.com/r/buildapc/s...)

If it’s properly seated etc.. could it be a pcie generation mismatch? If the card has a mismatch between what pcie generation it is vs your motherboard default, then you might have to manually set it correctly in the bios. This was a thing for GPUs a while back