Chris Wells

@asscr.bsky.social #ASSCR2025 conference has been great - terrific science, networking and location. Join us for #ASSCR2026 in Melbourne, 9-11 November, 2026. See you there!

ChatGTP empowered Chemical screening platform www.chemperturbdb.com

The final keynote of #ASSCR2025 from @shuibingchen.bsky.social on building pancreatic islet with beta cells, blood vessels and macrophages. doi.org/10.1016/j.st...

A village in a dish model system for population-scale hiPSC studies The mechanisms by which DNA alleles contribute to disease risk, drug response, and other human phenotypes are highly context-specific, varying across cell types and different conditions. Human induced pluripotent stem cells are uniquely suited to ...

Drew Neavin #ASSCR2025 using 'village in a dish' models to study the genetics underpinning cardiotoxicity Unpublisjed data so reference is to the village in a dish model. pmc.ncbi.nlm.nih.gov/articles/PMC...

Ralph Patrick is looking for dosage-sensitive transcription factors that may impact ageing #ASSCR2025 doi.org/10.1016/j.cm...

Luke and collaborators takes it further by exploring TF/chromatin structures to identify cofactors of P53 #ASSCR2025 doi.org/10.1016/j.mo...

Mechanisms of OCT4-SOX2 motif readout on nucleosomes Site-specific nucleosome engagement by pluripotency factors reveals how transcription factors distort nucleosomes at chromatinized motifs.

Try doi.org/10.1126/scie... Luke Isbel #ASSCR2025

Luke Isbel exploring chromatin codes in pluripotency #ASSCR2025 doi: 10.1126/science.abb0074

Refate identifies chemical compounds to target trans-regulatory networks for cellular conversion Identifying chemical compounds that target trans-regulatory networks (TRNs) underlying molecular programs of cells for directed cellular conversion (i.e. differentiation, reprogramming, transdifferent...

Kathrine Zyner presents 'ReFate' #ASSCR2025 which combines gene regulatory networks with compounds that impact on these regulatory pathways to improve cell reprogramming @biorxivpreprint.bsky.social doi.org/10.1101/2025...

Automated Integration of Multi-Slice Spatial Transcriptomics Data in 2D and 3D The field of spatial transcriptomics is rapidly evolving, with increasing sample complexity, resolution, and tissue size. Yet the field lacks comprehensive solutions for automated integration and anal...

Preprint @biorxivpreprint.bsky.social doi: doi.org/10.1101/2023... #ASSCR2025

Meet the winners of our 2025 Metcalf Prizes for Stem Cell Research: stemcellfoundation.net.au/2025_metcalf...
🧠 Dr Maria Di Biase @unimelb.bsky.social
🧠 Dr Lachlan Harris @qimrb.bsky.social
They're already making headlines ahead of the award ceremony on the Gold Coast today. @asscr.bsky.social

Hear from our 2025 #MetcalfPrizes winners – Dr Maria Di Biase and Dr Lachlan Harris – on ABC Radio Gold Coast Drive with Bern Young. Listen from 43.51 on yesterday’s show: www.abc.net.au/listen/progr...
@qimrb.bsky.social @unimelb.bsky.social @asscr.bsky.social

Day 3 #ASSCR2025 opens with Fernando Rossello benchmarking PSC-derived organoids using spatial profiling platforms. Lovely to see careful QC associated with this study.

How would you like to apply your passion for #bioinformatics to a real-world research problem?

We co-supervise PhD students in a wide variety of research groups across the University of Melbourne and the Melbourne Biomedical precinct.

If you're interested in doing a PhD with us, get in touch!

Inspiring #ASSCR2025 talk from Siok Tey @qimrb.bsky.social about home-grown clinical trials and manufacturing processes for new CART therapies.

Great first day of stem cell science on the beach at #ASSCR2025! Here is our @asscr.bsky.social president opening the conference. Highlights include keynote from @josh-brickman.bsky.social and presentation of @ausstemcell.bsky.social 2025 Metcalf awards. Congratulations to the worthy recipients!

Stem cell selfie #ASSCR2025 #miltenyibiotec @miltenyibiotec.bsky.social

Meet our Early Career Editor at #ASSCR2025! Pengyi Yang is attending the Australasian Society for Stem Cell Research (ASSCR) Conference in Gold Coast, Australia, 10-12 November 2025. Connect with Dr. Yang to discuss whether your research is a fit for publishing in Stem Cell Reports!

🌟 Congratulations to our 2025 #ASSCR Rising Star Award winners – Dr Ana Núñez Nescolarde (Harry Perkins Institute) & Dr Kevin Law (Universty of Sydney)! 👏
Honoured for excellence in stem cell research & leadership.
Thanks to NSCFA for their support! 🧬✨
#StemCells #RisingStars

Day 2 @asscr.bsky.social #ASSCR2025 opens with my favourite cell type (thanks Ed Stanley!) -iPSC derived macrophages. Ed is creating the cell types needed for a type1 diabetes model

Shalin Naik @shalinhnaik.bsky.social starting with a quick ad for their recently published LoxCode mouse, before discussion of clonal hematopoiesis - introducing the concept of lineage-primed HSC. #ASSCR #CloneOfDestiny

Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells Hematopoietic stem cells (HSCs) derived from human induced pluripotent stem cells (iPS cells) have important biomedical applications. We identified differentiation conditions that generate HSCs defined by robust long-term multilineage engraftment in ...

Ritika Saxena @ritikasxn.bsky.social speaking about hPSC-derived blood. pmc.ncbi.nlm.nih.gov/articles/PMC... @asscr.bsky.social #ASSCR2025

Can't get more Australian than a talk on marsupial pluripotent stem cells from Gerard Tarulli from the TIGGR labs @asscr.bsky.social #ASSCR2025 - describing iPSC from the fat tailed Dunnart. tigrrlab.science.unimelb.edu.au

Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing The rapid growth of single-cell transcriptomic technology has produced an increasing number of datasets for both embryonic development and in vitro pluripotent stem cell-derived models. This avalanche of data surrounding pluripotency and the process ...

Deep learning / autoencoder models of early development, recently published in @natmethods.nature.com pmc.ncbi.nlm.nih.gov/articles/PMC... #ASSCR2025

Josh Brickman @josh-brickman.bsky.social opens ASSCR with a provocative talk on transcription factor residency in early development.

The annual scientific meeting of Australian and NZ StemCell scientists is kicking off this week @asscr.bsky.social #ASSCR2025

Transitions is the newest in our series of stem cell conversations. Launched by Ritika Saxena, Jarmon Lees and @osvaldoics.bsky.social we explore project and career transitions. All the parts needed for successful science that don't make it to the bench. For Aussie scientists, but all welcome.

We are celebrating 5 years of the Australia stem cell conversation! Hosted by @unimelb.bsky.social and @asscr.bsky.social the stem cell conversation is a weekly 30min virtual seminar series organised by EMCR for EMCR.
Join the first 'transitions' episode Leadership through Service: 11am AEST Wed.

How FAIR is metadata for human pluripotent stem cells? In this article, Wells and colleagues present the first systematic FAIR evaluation of stem cell data infrastructures. Case studies from, but not limited to, the United States, Japan, Europe, and Austr...

New from the lab - How FAIR is metadata for human pluripotent stem cells? Registered cell lines are more likely to be cited, shared and reused across different studies - but most lines are difficult to find or lack key information. Stem Cell Reports www.cell.com/stem-cell-re...

A woman speaks to an audience about the importance of leveraging local experts in global science missions

Day 2 #HCA2025GM day two demonstrates the power of global representation in genome and cell maps. @patriciasevero.bsky.social