Structure and assembly of the A-C linker connecting microtubule triplets in centrioles
Multiscale cryo-EM of centrioles reveals the structure and polymorphism of the A-C linker connecting microtubule triplets.
Huge congratulations to Wieczorek Lab PhD student Bin Cai and now-PI Jingwei Xu @xujwet.bsky.social on figuring out the surprisingly complex structure of the A-C linker crosslinking microtubule triplets in Tetrahymena basal body centrioles! www.science.org/doi/10.1126/...
10.10.2025 13:13 β π 23 π 8 π¬ 1 π 1
Ken A. Dill to Receive Biophysical Societyβs 2026 Founders Award buff.ly/OZ3VUIk
24.09.2025 20:15 β π 15 π 4 π¬ 1 π 0
Apply - Interfolio
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Stony Brookβs Laufer Center for Physical & Quantitative Biology invites applications for an endowed faculty position (assistant/ associate professor). Join a top interdisciplinary hub in quantitative biology! Apply by Dec 1: apply.interfolio.com/173357
17.09.2025 17:45 β π 1 π 0 π¬ 0 π 0
Megan Elizabeth Kelley, PhD
Sfeir Lab/ Molecular Biology
Losing our edge: Combating drug resistance in cancer
Itβs SHOW TIME! π€ Kicking off the MSK Postdoc Slam is @meganekelley.bsky.social from the @agnelsfeir.bsky.social lab, diving into how error-prone DNA repair fuels drug resistance in cancer π§¬π
15.09.2025 20:09 β π 5 π 4 π¬ 0 π 0
Microscopy Training Grants
Supporting microscopy training for early-career researchers in cell biology
Apply for a grant of up to Β£1,000
Cartoon of a person looking down a microscope, which is next to a computer
Journal of Cell Science logo and FocalPlane logo
π’Last few days to apply for this round of our #microscopy training grants with @jcellsci.bsky.social
Available to ECRs working on #cellbio to attend a microscopy or bioimage analysis training course.
Apply by 5 September
www.biologists.com/grants/jcs-f...
29.08.2025 13:14 β π 11 π 7 π¬ 0 π 0
New preprint online!
So much fun working on this project, thank you @centriolelab.bsky.social and @dudinlab.bsky.social for embarking me on this one!
Hopefully HAK-actin will become your best companion for actin staining U-ExM expanded samples.
28.08.2025 07:26 β π 12 π 4 π¬ 1 π 0
Opportunities | Biochemistry & Cell Biology
Department of Biochemistry and Cell Biology at Stony Brook University
Hey #biology #postdocs out there, are you worried about the academic job market in the current climate? Do not! We are hiring, and we are an absolutely AWESOME department! π§ͺ
Apply now: www.stonybrook.edu/commcms/bioc...
15.08.2025 19:32 β π 2 π 4 π¬ 0 π 0
A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie
π¨ JOB ALERT π¨
We're hiring a Research Assistant β no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired π§«π¬
Apply now π www.nature.com/naturecareer...
#STEMCareers #ResearchJobs
23.06.2025 13:00 β π 48 π 32 π¬ 1 π 5
Iβm excited to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @science.org ! (link at end of π§΅)
23.05.2025 19:56 β π 197 π 46 π¬ 8 π 1
MuΓ±oz-HernΓ‘ndez, Xu, et al. @mike-wieczorek.bsky.social @ethz.ch report #cryoEM structures revealing how NEDD1βs C terminus forms an Ξ±-helical tetramer that docks onto the Ξ³-TuRC without inducing major conformational changes in the complex during its recruitment to MTOCs rupress.org/jcb/article/...
21.05.2025 16:10 β π 19 π 10 π¬ 0 π 1
We've developed a single-molecule imaging approach to study how #influenza A viruses interact with live cells at the nanoscale. We found that cellular receptors show a specific organization and turnover at the virus-cell interface. π www.nature.com/articles/s41...
@combinemarvproject.bsky.social
08.05.2025 07:19 β π 22 π 3 π¬ 1 π 1
In developing embryos, cells move a lot! Plenty of that movement is random. Is random cell mixing a feature or bug for tissue patterning? Turns out, itβs both! Excited to share the 1st preprint from my postdoc w/ Sean Megason @seanemcgeary.bsky.social and Allon Klein. 1/20 doi.org/10.1101/2025...
24.04.2025 13:18 β π 120 π 34 π¬ 7 π 6
New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work! www.biorxiv.org/content/10.1...
23.04.2025 14:04 β π 129 π 42 π¬ 3 π 4
Happy to officially introduce FilaBuster - a strategy for rapid, light-mediated intermediate filament disassembly. Compatible with multiple IF types, modular in design, and precise enough to induce localized filament disassembly in live cells.
www.biorxiv.org/content/10.1...
22.04.2025 01:02 β π 124 π 36 π¬ 2 π 6
Angewandte Chemie, a journal of the German Chemical Society (@gdch.de), is a leading journal in #chemistry published by Wiley-VCH (@wiley.com) in Weinheim, Germany
https://onlinelibrary.wiley.com/journal/15213773
A scientific journal publishing cutting-edge advances at the intersection of the life and physical sciences. Posts by the editors.
Head of the Budin lab at UCSD (www.budinlab.com). Musings on thin layers of grease in our cells (and other topics). Lipids, cell membranes, biophysics, chem bio, evolution. π³οΈβπ
Hopeless mitochondriak. Professor at McGill Neuro_MNI. Opinions my own.
Group leader @Westlake University #teamtomo https://en.westlake.edu.cn/faculty/jingwei-xu.html
https://jingweixulab.com
Postdoc at Pilhofer Lab @pilhoferlab.bsky.social, ETH Zurich. PhD at Tsinghua University.
CNRS researcher @IGDR, Rennes. Mitochondria lover, FRET/FLIM and biosensor aficionado. Views my own.
regeneration | evo-devo | menstruation
Postdoc @ Harvard SCRB
Former BIF PhD fellow @ IGFL (Lyon, FR)
BSc & MSc @ BoΔaziΓ§i University (Ist, TR)
Biophysics of cells and tissues
Light microscopy facility staff with interest in learning and sharing information about sample preparation, image acquisition, and image display best practices. Keen interest in Expansion Microscopy.
Cytoskeleton; microtubules; motors; Drosophila
https://www.gelfandlab.org/
Official account for the Biophysical Society, founded in 1958 to lead the development and dissemination of knowledge in biophysics.
Science and fun from the lab of Tony Hyman at the MPI-CBG @mpicbg.bsky.social. Tweets by Hymanlab members.
https://hymanlab.org/
senior scientist at Janelia | single particle tracking & #microscopy π¬ | PhD on single-molecule enzymatic dynamics | my path: π©πͺβπΊπΈβπΈπͺβπΊπΈ | https://scholar.google.com/citations?user=UzGfR3MAAAAJ&hl=en
Researcher in MeLiS - Lyon. Likes centrioles, cilia and anything graviting around those
Group Leader at Max Planck Institute for Molecular Genetics
Studying genome organization with quantitative super-resolution microscopy
https://www.molgen.mpg.de/stein-lab
Cancer cell biologist @ MSKCC / NCI K99 fellow / π¨π¦ in NYC
Cell Biologist interested in fundamental cell division processes working @iiscbangalore
Assistant Prof | Harvard Stem Cell and Regenerative Biology
Freeman Hrabowski Scholar | HHMI
Founder | Leading Edge @leadingedgeprogram.bsky.social
My lab studies menstruation and menstrual disorders.
www.mckinleylab.org
www.leadingedgesymposium.org
Organic chemistry passionate π§ͺ, mountain addict π§ & freediver π€Ώ. EPFL scientist and @spirochrome.com co-founder. π¨π
Professor, Physiology Department, Perelman School of Medicine, University of Pennsylvania. https://www.lakadamyali-lab.com
Super resolution microscopy, single molecule biophysics, microtubules, organelles, nucleus and chromatin