Lina Carlini's Avatar

Lina Carlini

@linacarlini.bsky.social

Assistant Professor, Laufer Center for Physical & Quantitative Biology, Stony Brook University

71 Followers  |  132 Following  |  1 Posts  |  Joined: 17.11.2024  |  1.5792

Latest posts by linacarlini.bsky.social on Bluesky

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Structure and assembly of the A-C linker connecting microtubule triplets in centrioles Multiscale cryo-EM of centrioles reveals the structure and polymorphism of the A-C linker connecting microtubule triplets.

Huge congratulations to Wieczorek Lab PhD student Bin Cai and now-PI Jingwei Xu @xujwet.bsky.social on figuring out the surprisingly complex structure of the A-C linker crosslinking microtubule triplets in Tetrahymena basal body centrioles! www.science.org/doi/10.1126/...

10.10.2025 13:13 β€” πŸ‘ 23    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1
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Ken A. Dill to Receive Biophysical Society’s 2026 Founders Award buff.ly/OZ3VUIk

24.09.2025 20:15 β€” πŸ‘ 15    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

Stony Brook’s Laufer Center for Physical & Quantitative Biology invites applications for an endowed faculty position (assistant/ associate professor). Join a top interdisciplinary hub in quantitative biology! Apply by Dec 1: apply.interfolio.com/173357

17.09.2025 17:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Megan Elizabeth Kelley, PhD
Sfeir Lab/ Molecular Biology
Losing our edge: Combating drug resistance in cancer

Megan Elizabeth Kelley, PhD Sfeir Lab/ Molecular Biology Losing our edge: Combating drug resistance in cancer

It’s SHOW TIME! 🎀 Kicking off the MSK Postdoc Slam is @meganekelley.bsky.social from the @agnelsfeir.bsky.social lab, diving into how error-prone DNA repair fuels drug resistance in cancer πŸ§¬πŸ’Š

15.09.2025 20:09 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Microscopy Training Grants
Supporting microscopy training for early-career researchers in cell biology
Apply for a grant of up to Β£1,000
Cartoon of a person looking down a microscope, which is next to a computer
Journal of Cell Science logo and FocalPlane logo

Microscopy Training Grants Supporting microscopy training for early-career researchers in cell biology Apply for a grant of up to Β£1,000 Cartoon of a person looking down a microscope, which is next to a computer Journal of Cell Science logo and FocalPlane logo

πŸ“’Last few days to apply for this round of our #microscopy training grants with @jcellsci.bsky.social

Available to ECRs working on #cellbio to attend a microscopy or bioimage analysis training course.

Apply by 5 September

www.biologists.com/grants/jcs-f...

29.08.2025 13:14 β€” πŸ‘ 11    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

New preprint online!

So much fun working on this project, thank you @centriolelab.bsky.social and @dudinlab.bsky.social for embarking me on this one!

Hopefully HAK-actin will become your best companion for actin staining U-ExM expanded samples.

28.08.2025 07:26 β€” πŸ‘ 12    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
Mechanical confinement governs phenotypic plasticity in melanoma - Nature Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state ...

My recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...

27.08.2025 17:18 β€” πŸ‘ 68    πŸ” 24    πŸ’¬ 6    πŸ“Œ 1
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Opportunities | Biochemistry & Cell Biology Department of Biochemistry and Cell Biology at Stony Brook University

Hey #biology #postdocs out there, are you worried about the academic job market in the current climate? Do not! We are hiring, and we are an absolutely AWESOME department! πŸ§ͺ

Apply now: www.stonybrook.edu/commcms/bioc...

15.08.2025 19:32 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg  and Julie

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired πŸ§«πŸ”¬
Apply now πŸ‘‰ www.nature.com/naturecareer...

#STEMCareers #ResearchJobs

23.06.2025 13:00 β€” πŸ‘ 48    πŸ” 32    πŸ’¬ 1    πŸ“Œ 5
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I’m excited to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @science.org ! (link at end of 🧡)

23.05.2025 19:56 β€” πŸ‘ 197    πŸ” 46    πŸ’¬ 8    πŸ“Œ 1
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MuΓ±oz-HernΓ‘ndez, Xu, et al. @mike-wieczorek.bsky.social @ethz.ch report #cryoEM structures revealing how NEDD1’s C terminus forms an Ξ±-helical tetramer that docks onto the Ξ³-TuRC without inducing major conformational changes in the complex during its recruitment to MTOCs rupress.org/jcb/article/...

21.05.2025 16:10 β€” πŸ‘ 19    πŸ” 10    πŸ’¬ 0    πŸ“Œ 1
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We've developed a single-molecule imaging approach to study how #influenza A viruses interact with live cells at the nanoscale. We found that cellular receptors show a specific organization and turnover at the virus-cell interface. πŸ‘‰ www.nature.com/articles/s41...
@combinemarvproject.bsky.social

08.05.2025 07:19 β€” πŸ‘ 22    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1
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In developing embryos, cells move a lot! Plenty of that movement is random. Is random cell mixing a feature or bug for tissue patterning? Turns out, it’s both! Excited to share the 1st preprint from my postdoc w/ Sean Megason @seanemcgeary.bsky.social and Allon Klein. 1/20 doi.org/10.1101/2025...

24.04.2025 13:18 β€” πŸ‘ 120    πŸ” 34    πŸ’¬ 7    πŸ“Œ 6
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New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work! www.biorxiv.org/content/10.1...

23.04.2025 14:04 β€” πŸ‘ 129    πŸ” 42    πŸ’¬ 3    πŸ“Œ 4
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Happy to officially introduce FilaBuster - a strategy for rapid, light-mediated intermediate filament disassembly. Compatible with multiple IF types, modular in design, and precise enough to induce localized filament disassembly in live cells.

www.biorxiv.org/content/10.1...

22.04.2025 01:02 β€” πŸ‘ 124    πŸ” 36    πŸ’¬ 2    πŸ“Œ 6

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