Rosaura Brisuela

Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩

Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.

A single dose of #psilocybin induces a rapid and sustained reversal of both mechanical allodynia (pain) and anxiodepression-like states in adult male and female mice

www.nature.com/articles/s41...

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1

Cracking organisms’ energy code Researchers define rules governing how growing microorganisms use energy efficiently

Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...

🧠📈 Do neurons of a feather flock together? Not quite.

New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.

📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...

The history and future of resting-state functional magnetic resonance imaging - Nature This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...

When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...

Hey Keri, some nuclei wear their emotions on their chromatin 🤭 I’m sure this is not in any epigenetic text books. Ironically, I captured this on a Lattice Light Sheet microscope a few years back which protects cell from phototoxicity.

Field notes from a weekend PI at the #microscope: vesicle cargo lanes lighting up in real time like @FedEx. This is the ML1N PX domain in a fibroblast. Hot damn, there’s mind-blowing action under the surface of cells: this video shows 2 min of time 🤯 #Cellbio #MicroscopyMonday #SciArt #SciComm

Age-related microbiome metabolites modulate splicing and chromatin accessibility in the brain https://www.biorxiv.org/content/10.1101/2025.10.03.680371v1

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy.
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)

I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...

Inside a cerebral organoid: a fluorescent lumen shines through 🧠✨ #FluorescenceFriday

#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data

Bringing some more ExM to #FluorescenceFriday with what appears to be a frustrated cell division in fibroblasts.

More details in Alt-text.

Image of a fluorescently labeled adult mouse kidney showing AQP2 staining of collecting ducts and connecting segment in green and alpha SMA staining of the arterial tree in magenta. The collecting ducts look like squiggly branches.

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

Deep Learning-Based Control of Electrically Evoked Activity in Human Visual Cortex https://www.biorxiv.org/content/10.1101/2025.09.24.678361v1

Heroico colegio militar mexicano #desfile2025

One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...

Thomas Deininger uses plastic waste to create sculptures,or should I say,works of Genius!!!!!!

Familial transmission of neural representations for mental arithmetic across two generations | PNAS www.pnas.org/doi/10.1073/...

The neural correlates of ongoing conscious thought Cognitive Neuroscience; Psychology; Techniques in Neuroscience

The neural correlates of ongoing conscious thought: iScience www.cell.com/iscience/ful...

YouTube video by Yonderboi - Topic Milonga del Mar

youtu.be/6SXPxa9l6N4?...

Sad to hear that Margaret Boden, pioneer in cognitive science and artificial intelligence, has passed away.

Just a few days ago, someone reactivated the post below. I warmly recommend watching the video.

Thank you Margaret for founding and shaping our field.

www.sussex.ac.uk/broadcast/re...

In new @jcb.org study from Muziyue Wu et al. @oweinerlab.bsky.social, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions. rupress.org/jcb/article/...

#Cytoskeleton #Actin #Migration #Motility #Biophysics