🧐 What if metabolic defects are not just a consequence of inflammatory disease - but actively contribute to it?
Inflammation and metabolism are deeply intertwined, but the molecular links remain unclear.
Our new paper in Cell Death & Differentiation uncovers one. 🧵👇
nature.com/articles/s41...
16.02.2026 12:00 — 👍 32 🔁 14 💬 2 📌 1
Join us for the #Ubiquitin & Friends Symposium 2026, April 29-30, in Vienna!
Fantastic guest speakers👇 & many slots for talks from abstracts, flash-talks & posters. Lots of opportunities to network. Register now to save your spot!
➡️ www.protein-degradation.org/symposium/
#ubfriends2026
10.01.2026 00:47 — 👍 34 🔁 21 💬 1 📌 3
We introduce #ProxiCapture, an affinity-proteomics platform to map degrader-induced interactions in native cell & tissue lysates. We uncover a context-dependent “glueable” proteome and a scalable route to accelerate molecular glue discovery 🤗
@ibc2-gu.bsky.social @goetheuni.bsky.social
06.01.2026 20:54 — 👍 28 🔁 14 💬 0 📌 0
We have an opening for a research support officer. Come and join us! Please share.
22.12.2025 12:09 — 👍 17 🔁 22 💬 0 📌 0
SAVE THE DATE!
The EMBO workshop "Ubiquitin and Ubiquitin-like proteins in Health and Disease" will be on September 2026.
Exciting line up of talks and an amazing location!
Organised by @kulathu.bsky.social, @merbllab.bsky.social, @simonapolo.bsky.social, Claudio Joazeiro.
Registration open soon.
08.12.2025 13:16 — 👍 24 🔁 18 💬 0 📌 0
UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6
Nature Structural & Molecular Biology - Riechmann et al. uncover structural features governing ubiquitin transfer from ubiquitin-activating E1 enzymes UBA1 and UBA6 to specific E2...
Excited to share our work into ubiquitin E1-E2 specificity mechanisms. CryoEM visualising #ubiquitin transfer,biochemistry,evolution @labhofmann.bsky.social & tissue expression analyses @psarkies.bsky.social Big thanks to the team,reviewers & handling editor @dimitristypas.bsky.social rdcu.be/eTRdR
09.12.2025 13:21 — 👍 37 🔁 15 💬 4 📌 2
Associate Professor at the Department of Biochemistry, University of Oxford. Fellow of Brasenose College.
Studying RNA binding proteins in cancer.
https://mardakhehlab.info
https://www.bioch.ox.ac.uk/research/mardakheh
A supportive network for the cilia and centrosome research community to share research and expertise.
https://www.cilianetwork.org.uk/
Studying kinetochores in African trypanosome (kinetoplastid) and marine plankton (diplonemid) in Edinburgh
https://www.ed.ac.uk/biology/groups/akiyoshi
PhD student at the MRC-LMB interested in proteostasis.
Postdoc @UW-Madison Weeks Lab | Ph.D. @Umich Narayan Lab
Predoctoral Research Assistant at the Llorca lab @cniostopcancer.bsky.social working on mTORC1 signaling and cryo-EM ❄️🔬. Intrigued by the structural mechanisms of protein assemblies involved in endomembrane signaling and trafficking 🧪.
Postdoc in the Sazanov lab at ISTAustria. Using structural biology to find meaning in a world ruled by microbes. 🔬🦠
Research Lab in the School of Molecular and Cellular Biology, University of Leeds. Focusing on all things weird and wonderful concerning SUMOylation.
Biochemist based in Aotearoa.
Group leader at MRC Human Genetics Unit, University of Edinburgh. Interdisciplinary research on disease #epigenetics. Part-time solo dad. Occasional music and climbing.
https://institute-genetics-cancer.ed.ac.uk/research/research-groups-a-z/sproul-group
Postdoc in the Musacchio Lab @ MPI-Dortmund. Cell division and everything that goes wrong with it. 🇪🇺 He/him
Ub and friends enthusiast
PostDoc in the Kulathu Lab
Group Leader @MRC_LMB /Structural Biologist/Biochemist. Amateur baker in free time #RNAworld #spliceosome #telomerase #telomeres #cryoEM #Xraycrystallography
Group Leader, MRC Laboratory of Molecular Biology & Joint Head of the Division of Protein & Nucleic Acid Chemistry. Senior Executive Editor, Nucleic Acids Research.
Connecting the global TPD and ubiquitin biology community. Discover research labs, explore conferences, and stay in the loop on everything from E3 ligases to molecular glues.
TPD research map:
https://tpd-community.com/
More formally, the Sir William Dunn School of Pathology, University of Oxford.
More understandably, we aim to transform human health through discovery research.
More completely, https://www.path.ox.ac.uk
We're the Crick, a biomedical research lab in London working to figure out how life works.
Home to more than 2,000 scientists and a free public exhibition space.
https://www.crick.ac.uk/
Ion Channel Biophysics, K+ Channels, OXION PhD programme, University of Oxford, Dept Physics & Kavli Institute for Nanoscience Discovery etc... But all views my own
The Carlyle Group @kavlioxford.bsky.social @oxforddpag.bsky.social, interested in the molecular mechanisms of resilience to Alzheimer’s disease and mental health problems. Feel free to DM us if you are interested — we would love to chat!
Lab of Molecular Neurodegeneration (Richard Wade-Martins), Oxford Parkinson's Disease Centre (@OxfordPDCentre) & Alzheimer's Research UK (@ARUKThamesV) Network.
