Mukund Sharma

You should join, this will be the best meeting of the year :)

15.09.2025 14:04 — 👍 11    🔁 3    💬 0    📌 0

Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival Glioblastomas are the most frequent and aggressive primary brain tumors. Current treatments invariably fail, a consequence of the pronounced heterogen…

Thrilled to share our new study from @joycelab.bsky.social on glioblastoma, the most aggressive brain tumor. Targeting ADAR1 slows tumor growth & mobilizes the immune system — a step forward for future treatments. www.sciencedirect.com/science/arti... 🔗 1/3

04.09.2025 08:06 — 👍 7    🔁 2    💬 1    📌 0

Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation The Elias Tillandz prize for the best scientific publication of 2024 was presented for two groundbreaking cancer studies.

Elias Tillandz Prize awarded at the BioCity Symposium to scientific publications on breast cancer recurrence and cancer gene overactivation www.utu.fi/en/news/pres...

28.08.2025 07:20 — 👍 4    🔁 2    💬 0    📌 0

We are on the cover! Or what is in the cover is way more important than we, it's evidence that simple IHC assay could be used for recognising #HNSCC patients based on their outcome after surgery-only therapy.
The actual cover and the article can be found here:
www.embopress.org/doi/full/10....

11.08.2025 10:50 — 👍 7    🔁 1    💬 1    📌 0

New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone Researchers developed a diagnostic test based on the LIMA1-alpha protein to distinguish patients with head and neck squamous cell carcinoma who can be cured with surgery alone, without the need for

Particularly proud of this collaboration with Sami Ventela and all Finnish #HNSCC clinics revealing LIMA1-alpha as translatable biomarker for selection of HNSCC patients for surgery-only therapies.
www.utu.fi/en/news/pres...
www.embopress.org/doi/full/10....

23.07.2025 07:42 — 👍 3    🔁 1    💬 1    📌 1

Generate beautiful PDF of your manuscripts easily using Markdown. #RxivMaker is here. We hope it will supercharge your #preprints Mojo.

27.06.2025 14:08 — 👍 24    🔁 8    💬 0    📌 0

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

23.06.2025 14:29 — 👍 68    🔁 87    💬 0    📌 7

Fantastic EACR @helloeacr.bsky.social annual congress in Lisbon. Great talks Great atmosphere Great to meet all old and new friends

18.06.2025 15:40 — 👍 1    🔁 1    💬 0    📌 0

June 6: The Week in Cancer News | Cancer Today A blood test can detect breast cancer drug resistance, and a combination treatment improves outcomes in colorectal cancer.

A blood test can detect breast cancer drug resistance, and a combination treatment improves outcomes in colorectal cancer. Learn about these and other stories from Cancer Today magazine's Week in Cancer News. www.cancertodaymag.org/cancer-talk/...

06.06.2025 20:03 — 👍 8    🔁 4    💬 0    📌 0

Congratulations 🎊

07.06.2025 09:36 — 👍 1    🔁 0    💬 1    📌 0

AstraZeneca unveils drug to treat mutating breast cancer before it starts to grow Pharma group estimates Camizestrant could be worth up to $5bn of sales in its peak year

AstraZeneca unveils drug to treat mutating breast cancer before it starts to grow—Professor @helink.bsky.social ‪ chief executive of the Institute of Cancer Research, said the results…  www.ft.com/content/9c3b... @hannahkuchler.bsky.social @financialtimes.com

03.06.2025 00:06 — 👍 6    🔁 3    💬 2    📌 0

Absolutely catapulting quadrable WEKK (Westermarck, Elenius, Kurppa, Kauko) retreat @Villa Wolax. Fantastic science, discussions, sauna, food, wine, colleagues @turkubioscience.bsky.social @medicity.bsky.social

02.06.2025 18:22 — 👍 5    🔁 3    💬 0    📌 0

LSD1 serine 166 is a phosphorylation switch for chromatin landscaping, gene activation, and tissue remodeling LSD1 is a histone 3 (H3) demethylase that can either repress or activate gene expression. We discover here that the so far enigmatic balance between these two activities in non-hormonal cancer cells i...

Delighted that my lab could contribute to this beautiful story by Jukka Westermarck's lab www.biorxiv.org/content/10.1...

19.05.2025 18:04 — 👍 6    🔁 1    💬 1    📌 0

New preprint from us.
The study led by Mukund Sharma demonstrates how #PP2A mediated dephosphorylation of serine 166 of LSD1 functions as a phosphorylation switch between gene repression and activation by LSD1 and how this shapes tumor microenvironment.
www.biorxiv.org/content/10.1...

18.05.2025 14:57 — 👍 4    🔁 2    💬 1    📌 0