Chris Pratt, PhD

Sorry, Phoenix airport. I know you’re trying to say “water is important,” but DNA is the DNA of life 🧬

Even for simple campaigns, subject matter expertise is important.
#copywriting #someoneShouldHaveReviewedThis

Sleep Apnea Linked to Brain Microbleeds Longitudinal study shows doubled incidence with moderate to severe obstructive sleep apnea

Obstructive sleep apnea is an insidious condition. Its impacts go beyond sleep quality, and a recent study connects OSA to microbleeds that could lead to dementia and cognitive impairments over time.

#SleepApnea #Medicine #Sleep

www.medpagetoday.com/pulmonology/sleepdisorders/118302

Treatment Complexity May Lower Medication Adherence in T2D Non-adherence to at least one prescribed antidiabetic drug is highly common among patients with type 2 diabetes and rises with the complexity of antidiabetic treatment.

A medication is only as good as adherence.

This is hardly a surprising result: patients less likely to be completely adherent to more complicated regimens. But it's something worth repeating.

#Diabetes #MedicationAdherence #Medicine #MedComms

www.medscape.com/viewarticle/...

A true hero... She changed how we think about so many things...

Be Loud — For America By Governor JB Pritzker

“Our country has survived darker periods than the one we are going through now—but that only happened because good people refused to stay silent. The attacks must end with Chicago. So I’m asking you, my fellow Americans across the nation: instead of being bystanders, be upstanders for our democracy“

I believe that the mounting pressure by many experts sounding the alarm on the threat of canceling the birth-dose of the hepatitis B vaccine contributed to the indefinite postponement of that vote by ACIP.
kKeep reminding folks that canceling the birth dose will kill children. Pressure works.

Trump Is Shutting Down the War On Cancer America’s cancer research system, which has helped save millions of lives, is under threat in one of its most productive moments.

A look inside the chaos from the NIH funding scene and how it is damaging research, especially in areas with smaller patient populations.

This will have long-term impacts on how we treat cancer and other diseases.

www.nytimes.com/2025/09/14/m...

Governor Pritzker speaks behind the podium.

In the coming days, we expect to see what's playing out in LA and DC happen in Chicago.

These efforts are not about fighting crime or making communities safer.

This is about Donald Trump testing his power and producing political drama to cover up his own corruption.

Today: CDC said ENOUGH.
We stand with them and for America.
#USAnotRFK Read & share this letter. Images or newsletter version below.

techingitapart.substack.com/cp/172217963

@niniandthebrain.bsky.social @enirenberg.bsky.social @unbiasedscipod.bsky.social @matthewfacciani.bsky.social

Use of Appropriated Funds for Illegal Lobbying and Partisan Political Activity by Federal Grantees MEMORANDUM FOR THE ATTORNEY GENERAL SUBJECT:       Use of Appropriated Funds for Illegal Lobbying and Partisan Political Activity by   Federal Grantees By

Attack on universities, de jour...

www.whitehouse.gov/presidential...

Universities get federal grants and universities lobby, ipso facto, universities are spending grant dollars for lobbying until proven otherwise.

Every reputable expert I know considers mRNA vaccine technology to be one of the most revolutionary advances in medicine in our lifetimes. Its inventors won the Nobel Prize in 2023. Shutting it down now is pointless self-harm to humanity.

Novel Anti-Amyloid Drug Aims to Outperform Current Standards Engineered to cross blood-brain barrier and scavenge plaques more effectively

This is encouraging! An interim analysis of a Ph1b/2a study of an investigational anti-amyloid antibody drug shows promising results in #Alzheimers! And this drug is given by IV.

#AlzheimerDisease #Neurodegeneration #Antibodies #Bispecifics #Medicine

www.medpagetoday.com/meetingcover...

🍂 👿 🏛️

Vagus Nerve Device OK'd for Rheumatoid Arthritis First of its kind to win FDA approval

A vagus nerve stimulator was approved for refractory rheumatoid arthritis, engaging a "neuroimmune reflex" to tamp down immune activity with a daily 60-second stimulation course.

www.medpagetoday.com/rheumatology...

So a government drowning in trillion-dollar deficits would borrow $150 billion more at 4.5% interest rates that taxpayers will be paying forever, in order to compensate us for higher tariff prices that they deny are actually happening. Makes sense.

Allergies seem nearly impossible to avoid — unless you’re Amish Despite the increasing rate of allergic diseases, both in industrialized and in developing countries, the Amish remain exceptionally - and bafflingly - resistant.

An interesting natural experiment showing immune exposure and entrainment.

“Farm dust contains a hodgepodge of bacteria shed from livestock and animal feed that isn’t harmful enough to cause illness, but does effectively train the immune system to become less responsive to allergens later in life.”

Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.

We need robust panels of experts to ensure impactful and high-quality science happens! This is another step toward the politicization and weaponizing of science.

This will impact the development of medicines, both on the academic and business side and will erode American science further.

I still can't get over the fact that "panels you point at sky and make electricity from sunlight with no fuel is the cheapest source of energy" needed explanation.

In 2007, I was in Finland taking biology courses taught in Swedish.

I sat in class with a dictionary on my desk just in case—occasionally frantically looking something up.

Now I get to relive that experience! Except this time it’s using Urban Dictionary to figure out what my kid just said... 🤔

I don’t think anyone is prepared for what they just did w/ ICE.

This is not a simple budget increase. It is an explosion - making ICE bigger than the FBI, US Bureau of Prisons, DEA,& others combined.

It is setting up to make what’s happening now look like child’s play. And people are disappearing.

"These are not serious, legitimate arguments by people who understand the science extensively. These are, generously, arguments that are made by people who don't really understand the epidemiology and how these vaccines are tested and evaluated."

www.medpagetoday.com/infectiousdi...

🏛️ Senate Budget Bill Now at US House of Representatives
🍃
Call your Reps - Tell them to Vote NO !!

Bill contains steep cuts to Medicaid, food stamps & clean energy funding, allocates $46.5 billion for border wall construction & $45 billion for detention of undocumented persons

Trump team axes contracts with publishing giant Springer Nature The action comes as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.

Political theater that will just continue to damage science.

The pay to publish model is a whole discussion, but axing government scientists’ access to reputable journals is outside that and it seems purely political.

Trump team axes contracts with publishing giant Springer Nature

If you’re asking for exemptions for your own state from the terrible policies in a bill—maybe the bill just isn’t good.

To put it lightly.

Sometimes you just have to refine through doing.

I wrote email templates this week. When I went to send them, I could see better where to adjust.

Putting them to use instead of just being “theoretical” changed my thought process, even if the substance was exactly the same. 🤔

Tirzepatide: a novel therapeutic approach for Alzheimer’s disease - Metabolic Brain Disease Tirzepatide (TRZ) is a dual agonist of glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptors that were recently approved for the treatment of type 2 diabetes (T2D) and…

🧠 Could tirzepatide protect the brain in Alzheimer’s?

This review argues that perhaps it could, at least based on preclinical studies.

Advisory Committee on Immunization Practices at a Crossroads In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...

Important read from all 17 highly qualified ACIP members who recently dismissed - read and share widely

jamanetwork.com/journals/jam...

RFK Jr. Names Replacements for CDC Vaccine Panel List includes COVID contrarians Robert Malone and Martin Kulldorff

I don’t think “restoring public trust in science” means what RFK thinks it means. Unsurprising that this list is largely a who’s who of COVID contrarians.

www.medpagetoday.com/infectiousdi...

Lean ≠ limited

I worked with a biotech that had just 10 in-house staff—but a full pipeline.

💡 They focused on science and outsourced execution.
🧫 CROs ran experiments
📣 External teams led comms + investor messaging

The right partners make the difference. #biotech #science #medcomms

Children infected with hepatitis B virus have 90% risk of developing chronic hepatitis.

30% of liver cancers are caused by chronic hepatitis B.

We have an incredibly effective vaccine. THAT’S why we vaccinate babies.

Weird: science DOES focus on improving health!

Grifters like Casey Means don’t.