Our new preprint 🧬🔗 www.biorxiv.org/content/10.1...
BRD4-NUT forms liquid-like condensates that locally constrain nucleosomes via BRD4-mediated crosslinking— physical control of #chromatin by #LLPS transcription condensates. @semeigazin.bsky.social @katsuminami.bsky.social @masaashimazoe.bsky.social
10.07.2025 04:21 — 👍 51 🔁 26 💬 1 📌 0
Congrats, Bruno!
03.07.2025 14:30 — 👍 1 🔁 0 💬 0 📌 0
Congratulations, Liling! A very exciting project!
21.05.2025 21:29 — 👍 1 🔁 0 💬 0 📌 0
Thrilled to share our new work on #aging in the murine hematopoietic system! There is a lot here- stem cell numbers, self-renewal rates, mutation rates, mutation signatures, clonal fitness, environmental effects...
06.03.2025 18:12 — 👍 37 🔁 8 💬 1 📌 0
In lab’s #FIRSTPREPRINT, we present methods to measure nanometer-scale organization around & between specific proteins in condensates in live cells. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.
28.02.2025 12:52 — 👍 47 🔁 13 💬 2 📌 1
** 3D chromatin ** gene regulation ** microscopy ** image analysis **
Postdoc with Ting Wu (HMS), PhD with Stephan Preibisch (BIMSB MDC) and Sevinc Ercan (NYU)
https://laurabreimann.github.io/
Assistant Professor @ Stanford University | cancer epigenetics | DNA replication | protein synthesis | vanrechemlab.com
Postdoc in Luca Giorgetti lab, FMI
Chromatin, Hi-C, gene regulation
Co-organizer of Sci.STEPS mentoring program
Professor and Director, Dept. of Biophysics & Biophysical Chemistry
Johns Hopkins School of Medicine, structural biologist, lover of chromatin and ubiquitin, fan of the active voice.
Neuroscientist+Child Neurologist. McNair Scholar #RareDisease, #neurogenetics, inhibition/circuits, #autism, #epilepsy, & brain disorders. RT≠endorse.
Assistant Professor at Baylor College of Medicine & Texas Children's Hospital | Human genetics and single-cell genomics | Formerly Columbia Med & Duke
Assistant Professor. Learning/memory/Behavioral Neuroscience. Brain Enthusiast. Worm Evangelist. Food and drink Fanatic. Views my own. She/her.
Website: https://www.areylab.com/
Learning how cells remember and forget, and how can we restore their memories @GENYO University of Granada, Spain. www.landeiralab.ugr.es
Group leader at @CRGenomica and @icreacommunity, interested in understanding the role of chromatin organization/function in stem cell biology and in disease.
Getting to grips with chromosome organisation and dynamics using ‘scopes, sequencing and silicon.
Located at @imbavienna.bsky.social - @viennabiocenter.bsky.social
#3Dgenome, #3R, #chromatin, #synbio, #microbiome... Opinions are my own.
Thoracic medical oncologist and cancer researcher at Dana-Farber/ Harvard Cancer Center
// Prev MSKCC Fellow, OHSU IM & Chief Res, Stanford Med, and UW-Madison
https://t.co/Y9HwVQ1jyq
The Fena Ochs Lab at the University of Copenhagen
3D chromatin function super-resolved
https://www.fenaochslab.org/
Medicinal chemist / chemical biologist, author of “In the Pipeline” at http://science.org/blogs/pipeline. derekb.lowe@gmail.com and on Signal at Dblowe.18
All opinions are mine; I don’t speak for my employer in any way.
Assistant Professor at Penn State University.
Looking at cool tiny complex things through electromagnetic lens.
Today, chromatin remodeling. Tomorrow? Who knows.
Opinions my own
INSERM research director & metabolism-lover, studying metabolism in cancer & immunity, Nice, France.
Editor-in-Chief of Oncogenesis www.nature.com/oncsis
#cancermetabolism #immunometabolism #mitophagy #CAR-T - www.c3m-nice.fr/en/Teams/team-03/
CNRS Senior Researcher - Group Leader at Laboratory of Biology and Modeling of the Cell, Ecole Normale Supérieure de Lyon.
Physical biology of chromatin: modeling the spatio-temporal dynamics of eukaryotic genomes.
Assistant Professor of Molecular Biology, Center for Alzheimer's and Neurodegenerative Diseases, UT Southwestern. My lab studies damaged things. Sometimes we fix them. Hiring! Write if interested in postdoc or tech position. https://www.davidwsanders.com
VP for Research, T.H. Smoot Professor
Depts Chemical and Biomolecular Engn, Pathology, Oncology, INBT
Johns Hopkins University
3D multi-omic, CAR T therapy, cell migration and mechanics
Lab: https://wirtzlab.johnshopkins.edu
