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Matthew Murphy

@mzchem-murphy.bsky.social

Mass spectrometry, metabolomics, lipidomics. Wannabe cyclist. Views are my own and not my employer’s.

373 Followers  |  490 Following  |  190 Posts  |  Joined: 02.12.2023  |  2.1799

Latest posts by mzchem-murphy.bsky.social on Bluesky

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Authorities Investigating Explosion on Harvard’s Medical Campus, Believed To Be Intentional | News | The Harvard Crimson A device exploded inside the Goldenson Building in Harvard’s Longwood medical campus early Saturday morning, according to a message from the Harvard University Police Department to University…

A device exploded inside the Goldenson Building in Harvard’s Longwood medical campus early Saturday morning, according to a message from the Harvard University Police Department to University affiliates.

Matan H. Josephy and Laurel M. Shugart report.

www.thecrimson.com/article/2025...

01.11.2025 18:11 — 👍 375    🔁 294    💬 7    📌 64

Deployment requires longer-term commitment to complete a working system at scale that does what was promised.
That’s a lot more difficult than demonstrating novel improvements at the bespoke level.
In the current econ/corporate environment, the latter is rewarded far more than the former.

01.11.2025 20:03 — 👍 0    🔁 0    💬 0    📌 0

Between this and the Louvre prosecutor describing the suspects’ statements as “minimalist” while bragging that they had worked on the case over a weekend it’s an absolutely incredible week for Frenchness

31.10.2025 13:18 — 👍 1294    🔁 339    💬 21    📌 8

q: why did the outfielders raise their arms during this play?

a: according to the ancient scrolls in which the rules of baseball were found, if a ball lands and doesn't bounce that ball is declared god. the players were worshipping god. i doubt there will be a game 7 or any further baseball seasons

01.11.2025 03:19 — 👍 2406    🔁 451    💬 29    📌 10
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a woman in overalls is dancing in front of a mirror with the word bravas on the bottom ALT: a woman in overalls is dancing in front of a mirror with the word bravas on the bottom

🤮🤮🤮🤮

I hate this for the world, because how many brilliant Ada Lovelaces have we lost because they were gurlz.

31.10.2025 23:54 — 👍 18    🔁 2    💬 0    📌 0

My wife has volunteered at a local food bank for years and confirms what many of you have probably heard: in this case, straight cash is a good donation if you can do it.

The food banks have better access and buying power than individuals do, and can try to address item imbalances as they see them.

31.10.2025 15:13 — 👍 169    🔁 51    💬 5    📌 3
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Expert Warns of Irreparable Damage to Biotech Industry Unless Congress Acts U.S. owes its 'vibrant pipeline' to high levels of public funding, says Aaron Kesselheim

From Senate hearing on Wednesday

www.medpagetoday.com/washington-w...

31.10.2025 01:50 — 👍 68    🔁 28    💬 1    📌 1

I can’t stress this enough: you cannot understand politics without reading this paragraph about why there’s no such thing as a 1/3rd pound hamburger

30.10.2025 02:26 — 👍 3536    🔁 1089    💬 85    📌 73

I wouldn’t be able to hit block sender fast enough with that email.

30.10.2025 02:29 — 👍 0    🔁 0    💬 0    📌 0

This is what the internet was built for. This and transferring important scientific data across the globe.

30.10.2025 02:23 — 👍 5    🔁 1    💬 0    📌 0

One of my favorite things about visiting the national parks are hearing all the languages of visitors who traveled from near and far.

29.10.2025 20:01 — 👍 1    🔁 0    💬 0    📌 0

They are also intentionally conflating machine-learning and generative AI slop to confuse and try to make GenAI seem necessary. Google Maps traffic stuff is machine learning, not GenAI, for example. Auto-correct is too. Don't let them make you lose the thread. GenAI slop is slop.

28.10.2025 18:44 — 👍 5204    🔁 2184    💬 6    📌 23
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The White House is asking people not to share pictures of the East Wing because it’s even worse today.

21.10.2025 22:54 — 👍 30065    🔁 16330    💬 2406    📌 1707
Paper by Asimov in JACS

Paper by Asimov in JACS

It’s easy to forget that Isaac Asimov was once just a biochemist. Journal of the American Chemical Society 1950. #bluesky 🧪

21.10.2025 00:57 — 👍 138    🔁 22    💬 11    📌 1
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GitHub - kronigert/timsCompare: A desktop application for mass spectrometry users to load, view, compare timsTOF methods and export isolation schemes and method reports from Bruker's .d method directo... A desktop application for mass spectrometry users to load, view, compare timsTOF methods and export isolation schemes and method reports from Bruker's .d method directories. - kronigert/timsCom...

timsCompare is free, open-source, and available now on GitHub! All feedback, bug reports, and feature ideas are welcome.

github.com/kronigert/ti...

#MassSpec #TeamMassSpec #Proteomics #timsTOF #diaPASEF #diagonalPASEF

(Disclaimer: This is an independent project, not an official Bruker tool.)

15.10.2025 11:01 — 👍 6    🔁 1    💬 1    📌 0
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Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as a key mediator of mitochondrial impo...

Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @cp-cellmetabolism.bsky.social www.cell.com/cell-metabol...

11.10.2025 16:15 — 👍 40    🔁 8    💬 2    📌 1
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Exploding pumps trigger Sciex mass spectrometer alert Global safety notice recommends shutdown of workhorse analytical chemistry tools

SciEx recalled a bunch of turbos in 2017 due to the potential of catastrophic turbo failure and two documented incidents that triggered the recall.

cen.acs.org/articles/95/...

14.10.2025 02:46 — 👍 0    🔁 0    💬 0    📌 0
Xevo CDMS: A New Era in Mass Spectrometry
YouTube video by Waters Corporation Xevo CDMS: A New Era in Mass Spectrometry

Not sure if this is THE first charge detection commercial MS release from a major vendor, but it’s certainly one of the first.

Analyses macromolecules from 100 MDa and beyond. No charge state deconvolution necessary.

www.waters.com/nextgen/au/e...

13.10.2025 11:18 — 👍 4    🔁 3    💬 2    📌 0
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A paucity of punches: why was punching so rare in pre-modern martial arts by Maxime Chouinard To most people, punching seems like one of the most natural ways of fighting when unarmed. Most movies will show protagonists and villains alike dealing numerous punches, and kn…

Today in historical hot takes: a well-supported argument that the straight punch was invented in early-modern Venice and likely didn't exist before that. hemamisfits.com/2025/10/05/a...

08.10.2025 17:56 — 👍 93    🔁 23    💬 7    📌 5
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The ‘Anthropological Change’ Happening in Venezuela Maduro is still in place, but a pro-democracy movement is transforming the beleaguered country.

Congratulations to Maria Corina Machado, recipient of the Nobel Peace Prize - her incredible optimism has already changed her country. I spoke to her, and wrote about her, at the beginning of this year:
www.theatlantic.com/internationa...

10.10.2025 09:59 — 👍 13080    🔁 3317    💬 306    📌 171

Big adventure in the yard today!

NATIVEPLANTGUY: *bent over to pull a weed* Yeah, I’ve been trying to catch these little weeds while they’re small—
ME: STOP
NPG: *freezes*
ME: Step back, slowly.
NPG: *steps back*
ME: Whew.
NPG: Rattlesnake, right? Where?
ME: *points*
NPG: …whoa.

09.10.2025 20:47 — 👍 1097    🔁 64    💬 34    📌 6

So, uhm, what's the track record of countries where members of the governing regime start clamoring for a "cleansing" of the political opponent?

Always remember: No matter how much they escalate the rhetoric, it doesn't mean they'll be able to do it. But let's not pretend they aren't trying.

07.10.2025 17:26 — 👍 935    🔁 264    💬 46    📌 8

Today is a day when arts degrees are worthless, but the product of those degrees is so valuable it would kill an entire industry if they were made to pay for it.

08.10.2025 10:29 — 👍 26630    🔁 10116    💬 426    📌 185
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Very excited to kick off the annual Skyline Online 2025 Small Molecule course with a keynote lecture by Gary Patti @gjpattij.bsky.social.
Showing how his lab and collaborators are advancing mass spectrometry to achieve parity with sequencing techs, supported by Skyline!

08.10.2025 13:57 — 👍 7    🔁 2    💬 2    📌 0

Can’t decide what to buy on Prime Day?

Try: absolutely nothing, and then go support indie bookstores instead 📚

07.10.2025 14:23 — 👍 7845    🔁 2819    💬 64    📌 159
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Jess Waters recycling the same guy over and over to represent “former” different enemies

06.10.2025 18:51 — 👍 8835    🔁 2930    💬 537    📌 480

This is great. The absurdity of this moment captured. Make it go viral.

07.10.2025 10:44 — 👍 6691    🔁 3162    💬 287    📌 138
Judge blocks South Carolina from giving DOJ millions of voters' data
Sep. 3, 2025

Judge blocks South Carolina from giving DOJ millions of voters' data Sep. 3, 2025

Judge's house on fire

Judge's house on fire

Judge Diane Goodstein crossed the Trump administration last month. Yesterday, her home burned, her husband was injured and it's being investigated for arson.

www.postandcourier.com/news/crime/s...

06.10.2025 00:39 — 👍 5252    🔁 2733    💬 133    📌 235
Text of the fourth amendment “The right of the people to be secure in their persons, houses, papers, and effects, against unreasonable searches and seizures, shall not be violated, and no warrants shall issue, but upon probable cause, supported by oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized.”

Text of the fourth amendment “The right of the people to be secure in their persons, houses, papers, and effects, against unreasonable searches and seizures, shall not be violated, and no warrants shall issue, but upon probable cause, supported by oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized.”

Just posting this. Everyone knows why.

05.10.2025 00:30 — 👍 5500    🔁 2166    💬 87    📌 81

My husband was detained by ICE today

Juan Muñoz, an American citizen, father of 2, and local government official, was peacefully protesting w. other elected officials. He was assaulted and taken away

I have had zero contact or updates since

#SOS
@duckworth.senate.gov @durbin.senate.gov

03.10.2025 17:12 — 👍 26564    🔁 13698    💬 768    📌 529

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