Rox Fox Sox

its back online! buy or wishlist if you ve been looking forward to it :)
store.steampowered.com/app/2701800/...
or on itch
papercookies.itch.io/no-players-o...

Oof, that's rough! Glad to see No Players Online back on Steam, though.

Y'all should check it out. It's one of those games that I don't want to spoil ANY part of, and probably even the store page and trailers tell you a bit much.

YouTube video by MUDRAT - Topic YOU DON'T CARE ABOUT POOR PEOPLE

I would say having this song playing after posting hits just right
music.youtube.com/watch?v=yg-6...

Forever disappointed that The Grinch become a consumer icon for corporations around the holidays

Contact your reps directly.

I keep seeing stuff about a petition and like, contact your reps directly. Sign that too if you want, but petition signatures are a lesser priority.

GOOD NEWS! Researchers have discovered a powerful antibody, known as 04_A06, that is able to neutralize 98.5% of MORE THAN 300 different HIV strains AND permanently reduce HIV viral load to undetectable levels, making it one of the broadest-acting antibodies against HIV identified to date.

ABSTRACT Administration of HIV-1 neutralizing antibodies can suppress viremia and prevent infection in vivo. However, clinical use is challenged by envelope diversity and rapid viral escape. Here, we performed single B cell profiling of 32 top HIV-1 elite neutralizers to identify broadly neutralizing antibodies with highest antiviral activity. From 831 expressed monoclonal antibodies, we identified 04_A06, a VH1-2-encoded broadly neutralizing antibody to the CD4 binding site with remarkable breadth and potency against multiclade pseudovirus panels (geometric mean half-maximal inhibitory concentration = 0.059 ug ml-1, breadth = 98.5%, 332 strains). Moreover, 04_A06 was not susceptible to classic CD4 binding site escape variants and maintained full viral suppression in HIV-1-infected humanized mice. Structural analyses revealed an unusually long 11-amino-acid heavy chain insertion that facilitates interprotomer contacts with highly conserved residues on the adjacent gp120 protomer. Finally, 04_A06 demonstrated high activity against contemporaneously circulating viruses from the Antibody-Mediated Prevention trials (geometric mean half-maximal inhibitory concentration = 0.082 ug ml-1, breadth = 98.4%, 191 virus strains), and in silico modeling for 04_A06LS predicted prevention efficacy of >93%. Thus, 04_A06 will provide unique opportunities for effective treatment and prevention of HIV-1 infection.

This finding potentially opens up new perspectives for the prevention and treatment of HIV infections.
• amp.dw.com/en/germany-n...

The study has been published in Nature Immunology. YES, it is PEER-REVIEWED.
• www.nature.com/articles/s41...

🧪🧵⬇️

People in my comments are saying they cant watch the video on their TV cause it talks about Suicide. Then I wake up to this.

I have a dumb job

Waiittttt I forgot I'm supposed to do this

IT'S MY BIRTHDAY! HERE ARE MY ARTS!!!! 🎂❤️❤️✨🙏

One more jolly year. What a privilege it is to grow old :D

Please be patient with small businesses today! I know it's Cyber Monday. But Shopify is having issues & it's affecting many small businesses. I've been having issues here and there since the additional tariffs were introduced. Today is the worst outage I've experienced so far.

Ngl it made me snort laugh while waiting to clock in at work.

Sayin' it now: if Amazon thinks that this is going to lead fans to say "this is the future," they have another thing comin'.

Our community was born in the old ways, and enough of us who were there from the pre-boom days are still around to the point that we can very feasibly return to them.

It's not even now about quick 'n' cheap new dubs but getting around additional licensing and paying residuals for existing ones.

But yeah, we have to keep the backlash against this hot and loud each and every time they try to do this.

A girl laying on the ground. Below in the ground is an image of a Glyptodon from ESO's Elsweyr chapter. Text says "We still talk about you".

a horse

MFF is allowing Erotic Exotics, a company that abuses animals to make adult toys, to vendor

They also have an event with the piece of shit and fascist PepperCoyote

Glad I’m not going, and it looks like I’ll never go back unless they fix some shit

Need a cool gift for your mom this holiday season? Commission me for something she can hold in her own two hands.

Thank you for the thread!
We're at $115 out of $400! I'd really appreciate it if we could get this need met before Christmas so I can actually walk outside when I own winter shoes.

I had to draw an INCREDIBLE dream I had the other night

"The agreement places no restrictions on our transgender community."

Except whether they can play sports, where they can use the bathroom or locker room, what kind of housing they can live in, and what healthcare they can receive.

my dude
my guy
my grumpy second sona

I love him
this was a fun sketch

#anthro #furry #artist #sketch #oc

Negotiations - Album by Kilo Kish Listen to Negotiations by Kilo Kish on YouTube Music - a dedicated music app with official songs, music videos, remixes, covers, and more.

Who else loves Kilo Kish?
music.youtube.com/playlist?lis...

MORE DRAGON BOY

bunny boy x 2
(HE/HIM)

YouTube video by F.D Signifier Charlie Kirk and the Conservative Death Cult

Finally got it up

youtu.be/-gMAHm8LBes?...