Gregor Weiss

Thanks Roland! 🙏🏼 how cool, I hope the students were also excited 😋 I was already looking forward to meet you in Switzerland this year :/ but I am sure at some point we will manage again to catch up! Florian, Nick and Martin are anyways always reporting about the amazing science going on in your lab!

Thanks Ben for your nice words and your support! This retreat is gonna be a blast and count us in 🥳 already looking forward to catch up!

It's been ~13 years ago in the lab of Grant Jensen, when Martin @pilhoferlab.bsky.social showed me how to prepare media, do first protein preps and negative stain EM. I had no idea how much more I’d learn from him over the next years - THANK YOU MARTIN for this incredible ride 🙏🙏🙏

This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered

Strategies and mechanisms of contact-dependent predation in bacteria Predatory bacteria kill other bacteria to acquire nutrients. Among diverse strategies to kill and feed on prey, contact-dependent predation stands out…

#MicroSky Summer read!

Predatory bacteria kill and eat other bacteria. Their deadly actions come in many flavors, often via direct physical contact between predator &
prey 🧛

How do they do it?
Our review 📖 @coralietesseur.bsky.social @ysantin.bsky.social

www.sciencedirect.com/science/arti...

Come and join Martin‘s Lab at the University of Zurich and become our colleague 🧫🔬

An Asgard archaeon from a modern analog of ancient microbial mats It has been proposed that eukaryotic cells evolved via symbiosis between sulfate-reducing bacteria and hydrogen-producing archaea. Here we describe a highly enriched culture of a novel Asgard archaeon...

Our new preprint with a new #Asgard from stromatolites (and its Desulfobacterota companion). Complete circularised genomes of both, cool #cryoem images, protein modelling, etc

Big group effort with a lot of people involved
#archaeasky #archaea
www.biorxiv.org/content/10.1...

A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries Cryo-electron tomography (cryo-ET) enables 3D visualization of complex biological environments without the need for purification, thereby preserving t…

Happy to say that my Current Opinion in Structural Biology article came out today. I hope it helps to guide to you in using cryo-ET to make new biological discoveries!

www.sciencedirect.com/science/arti...

Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA CryoEM, genetic, and cell biological analyses reveal that the conserved membrane protein CisA mediates membrane recruitment of contractile injection systems Streptomyces coelicolor, enabling their act...

Happy to see our collaborative work on the contractile injection system (CIS) in Streptomyces published. We show that the membrane protein CisA gives Streptomyces CIS a licence to kill.
@pilhoferlab.bsky.social & Bastien Casu, @joesallmen.bsky.social #MicroSky

elifesciences.org/articles/104...

Excited and honored to be joining the EMBO Member community 🥳 Congratulations also to all the other newly elected members! -Martin

#cryoET folks, this is your chance to combine a beautiful location 🏔️ with cutting-edge imaging of weirdo microbes 🦠 Florian is an amazing colleague & scientist and I am sure he will also show you how to 🎿🚵🏼🏃‍♂️🍺

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

In-cell architecture of the mitochondrial respiratory chain Mitochondria regenerate adenosine triphosphate (ATP) through oxidative phosphorylation. This process is carried out by five membrane-bound complexes collectively known as the respiratory chain, workin...

buuuh... thanks for pointing this out. Let's try this one: www.science.org/doi/10.1126/...

A great day for #teamtomo
First, @cellarchlab.com shows the beauty of the mitochondrial respiratory chain (www.science.org/doi/10.1126/....
... and now my colleagues @florianwollweber.bsky.social & @xujwet.bsky.social visualized tubulins in Asgard archaea 😍🤯 www.cell.com/cell/fulltex...

We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾

Press release from @unibas.ch and @biozentrum.unibas.ch about our new #cryoET study on mitochondrial respirasomes. Led by the unstoppable @florentwaltz.bsky.social 🙌

🧪🧶🧬 #TeamTomo

Eukaryotes' closest relatives are internally simple syntrophic archaea Eukaryotes are theorized to have originated from an archaeal phylum Promethearchaeota (formerly 'Asgard' archaea)1,2. The first cultured representatives revealed valuable insight3,4 but are distantly ...

Check out 👀 this awesome preprint on new cultures of Asgard (Hod) archaea with beautiful 🔬 images by Imachi et al. www.biorxiv.org/content/10.1...

Small Things Considered wrote a blog post about our recent findings on bacterial predation. Thanks a lot @stcmicrobeblog.bsky.social for highlighting captain Aureispira 😊🏴‍☠️

Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍

Preprint📜: www.biorxiv.org/content/10.1...

A short thread🧵👇

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation - Nature Microbiology Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation.

Details here 👇
www.nature.com/articles/s41...

Thank you Roland! I heard you are coming to Switzerland next year, amazing. I will be at the conference too, already looking forward 🤩

Thank you Max! Hope to catch up with you at some conference again! 🍺

Extremely grateful to all my current group members for their amazing work, but especially to Martin and all @pilhoferlab.bsky.social members for the past 12 years. New adventures ahead 👨‍🏫

Thanks to an @snf-ch.bsky.social Starting Grant, my group will move to the Institute of Medical Microbiology at University of Zürich in summer 2025.
Let's move cryoET literally next to the clinics and investigate bacterial pathogens from molecules to the patient #FreezeInTheClinics 🏥❄️🔬

Is there still space? :) would be great if you could add me 🙏🏼

Would be great if you could add me and the Pilhofer lab as well :) thanks a lot for putting this together!

It’s wildin’ out there in the microbial world 💀🦠 - with Aureispira grappling and stabbing 🔪🩸 and Yersinia sacrificing themselves 🫥🤕 Now, it’s time we expose the violent tendencies 🥷 of a salty 🧂 #archaea in our new paper in Science Advances! www.science.org/doi/10.1126/... 🧵1/5 #cryoET #teamtomo