Anastasia Baryshnikova

Regeneron buys 23andMe out of bankruptcy Drugmaker’s takeover comes less than two months after start-up filed for protection

Regeneron buys 23andMe out of bankruptcy

https://www.ft.com/content/362bcad4-8f4a-42b4-ab86-38821d74352f

Genetic suppression interactions are highly conserved across genetically diverse yeast isolates Sometimes the detrimental effects of a mutation can be rescued by another mutation. For genetic diseases, such suppressor mutations may identify new therap

The latest work of PhD student Claire Paltenghi
@fbm-unil.bsky.social @unil.bsky.social @umasschan.bsky.social, on the conservation of genetic suppression interactions across genetic contexts, now published in G3 @genetics-gsa.bsky.social: doi.org/10.1093/g3jo...

My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful.

It’s available on Amazon: tinyurl.com/mx2hewen

Thank you!

A huge thanks to our new collaborators who helped bring this story across the finish line – Katie Cardone, @rachitk.bsky.social, @marylynritchie.bsky.social, and @ksusztak.bsky.social.

Our updated APOL1 manuscript just went live on #bioRxiv – perfectly timed with #APOL1AwarenessDay (April 29). We've sharpened our hypothesis and focused the supporting evidence for a clearer story.

#APOL1 #KidneyResearch #UKBiobank #pQTL

www.biorxiv.org/content/10.1...

Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model Phenotypic variation arises from the interplay between genetic and environmental factors. However, disentangling these interactions for complex traits remains challenging in observational cohorts such...

New pre-print klaxon: "Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model" led by the excellent Bettina Welz + @saulpierotti.bsky.social from @wittbrodtlab.bsky.social, Felix Loosli, Kiyoshi Naruse and my own lab www.biorxiv.org/content/10.1...

Postdocs: Human Genetics at Utah will be hosting our annual Rising Stars in Genetics and Genomics Symposium in Sept. Apply here: shorturl.at/wBMg2
There will be sessions on developmental, evolutionary and disease genetics. A chance be invited to SLC to network here and with peers! Please share.

An under-appreciated perk of AI-aided coding: the consistent positive encouragement you rarely get IRL! Just finished a co-coding session with ChatGPT and it signed off with "Good luck with your project -- it's shaping up beautifully 🙌". Needed that!

#AICoding #DeveloperLife #ChatGPT

Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out!
meetings.cshl.edu/courses.aspx...

Platform-dependent effects of genetic variants on plasma APOL1 and their implications for kidney disease Mutations in apolipoprotein L1 (APOL1) are strongly associated with an increased risk of kidney disease in individuals of African ancestry, yet the underlying mechanisms remain largely unknown. Plasma...

New preprint! Our latest work on plasma proteomics in UKBB helps unraveling the fascinating connection between APOL1, parasite resistance, and kidney disease.

www.biorxiv.org/content/10.1...

#APOL1 #KidneyDisease #Plasma #Proteomics #Genetics #Biomarkers #KallikreinKinin #AfricanAncestry #UKBB