Amy C Fan (she/her)

The NIH budget will INCREASE by $400 million — not slashed by 40%, as Trump proposed — according to a proposal by Senate appropriators, says Sen Murray.

"Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.

Macrophages kind of look like gastly (the Pokémon)

Macrophage photo credit: Cell Wiki

How do I cry react to this instead of heart it

Thank you for this psa

Controlled colonization of the human gut with a genetically engineered microbial therapeutic Precision microbiome programming for therapeutic applications is limited by challenges in achieving reproducible colonic colonization. Previously, we created an exclusive niche that we used to engraft...

Engineering the gut microbiome in people with hyperoxaluria to avoid kidney stones
science.org/doi/10.1126/...
@science.org

I love this and am going to start doing it

New research from @stanfordmedicine.bsky.social reveals a gene signature that can predict severe illness before infection even happens. Featuring #StanDOM's Purvesh Khatri. stan.md/4k8qIT9

Anyone have experience with IV mRNA-LNP vaccination in animals? I am specifically interested in LNP formulations and what the preferred formulation for IV is.

New endosomal protein network resource: bit.ly/endomapv1

Importantly, interaction networks are informed by *multiple* proteomic methods to capture interacting proteins and alphafold structural predictions.

Bonus: validation of new interactions in neurons: nature.com/articles/s41586-025-09059-y

An illustration of a woman riding a large turtle with a stack of papers behind her. Text reads: My Ph.D. took a long time—and there's no shame in that

"No one’s Ph.D. journey is the same, and no one deserves to be shamed for how long it takes." #ScienceMagArchives scim.ag/44q2rCg

Applying to Biology PhD programs this year? Let us help!

At BPP, we aim to support students from all backgrounds through the grad school application process. Learn more about grad student life and receive 1-on-1 feedback on your application materials!

Apply here: forms.gle/EvTyUWXFMRSL...

Would love to look at ex vivo macrophage subsets and also how this is regulated in tissues. Let me know if you have any ideas for approaches for the in vivo experiments!!

So far, it looks like all of the macrophages phagocytose (though to varying amounts) but only a subset of those sampled from live cells.

In vitro cultures also indicate that macrophage subsets perform live sampling with different efficiencies.

Yes! So far, I haven't been able to find something that enables us to distinguish between efferocytosis vs. this type of sampling. However, I have done a few in vitro experiments feeding macrophages both live and dead cells (labeled with different colors).

Very excited to read this spot-on feedback. We are actively investigating the molecular mechanism and physiological implications of this process, so we hope to shed some light on these questions soon!

Come find me presenting this project as a poster at #KSAutophagy25 if you would like to chat!

On Juneteenth, and in this era of rising vaccine disinformation,
it is useful to contemplate that three centuries ago, the knowledge of an African slave introduced the concept of immunization to America, launching the first successful public inoculation campaign 

🧵Thread 1/8

#Juneteenth #Vaccines

The 2025 Freeman Hrabowski Scholars | HHMI Freeman Hrabowski Scholars are outstanding early career faculty who have the potential to become leaders in their research fields.

Congratulations to all the amazing scientists named 2025 Freeman Hrabowski Scholars by @hhmi.org! We’re proud to have to #BlackInBiophysics faculty members, @doctheagrif.bsky.social and @cobarnes27.bsky.social among this outstanding group. We wish you the best in this next stage of your careers! 👏🏾👏🏾👏🏾

Continuing our interview spotlight series is the 2025 McCulloch and Till Awardee @steidluli.bsky.social‬ Dr. Steidl discusses his current work, career inspirations and more. Watch part III on www.simplyblood.org

Applications now open!
The Graduate Diversity Enrichment Program (GDEP) provides $5,000 over two years to provide PhD students (enrolled in NC Institutions of Higher Education) opportunities for greater science & research enrichment experiences.
buff.ly/sJ7c6pI
#bwfgdep

Good luck! Fingers crossed for you.

The Age of Aquaticus Podcast Episode · Radiolab · 04/25/2025 · 43m

A 1966 NSF grant of $80,000 finds totally unexpected “thermophile worms” living in Yellowstone’s hot springs. The discovery sits on a shelf till 1983, before becoming key to the development of PCR genetic testing.

Invest in basic research. @radiolab.bsky.social

podcasts.apple.com/us/podcast/r...

The #SimplyBlood Interview Spotlight Series continues with the 2025 Janet Rowley Award Winner Adam Wilkinson! Watch the interview now and register for #ISEH2025 🏯 to hear about his work in person. www.simplyblood.org

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy.
Details found here👇

www.queensu.ca/grad-postdoc...

The New York Times insists on treating Christopher Rufo not as a far-right activist who has been successfully pushing an ideologically defined rightwing agenda, but as a respectable conservative voice and a serious interlocutor on key political issues.

That is an active, deliberate choice.

Either way — congrats!!

@timothykeyes.bsky.social ❤️

With the social event and scheduled networking activities, #ISEH2025 🏯 has something for everyone! Check out what we have planned and add these events to your registration ➡️ www.iseh.org/2025SocialNetworking

Saddened to hear of the death of Jim Till, at age 94. He was the co-discoverer of transplantable stem cells (with Ernest McCulloch), a discovery that revolutionized cancer treatment. www.legacy.com/ca/obituarie...
www.cdnmedhall.ca/laureates/ja... via @pmresearch-uhn.bsky.social

The War Keeps Raging Against Science Science Vs · Episode

NEW SCIENCE VS EPISODE out discussing what's going on with U.S. science under the Trump administration — and how scientists are fighting back. We hear from fan fave @maxkozlov.bsky.social at @nature.com.

PLUS: Does funding science do anything for the economy?🧪

open.spotify.com/episode/4A9A...

Not getting much attention, except in a recent NYTimes story, is a provision to increase the tax on university endowments and those of other nonprofits.