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Brian Mueller

@brianscience.bsky.social

Visiting Postdoc @Charite @MPI-NAT| PhD @UUtah | CUBoulder ‘13. Calcium channels, release machinery, and synaptic function. (he/him)

372 Followers  |  1,412 Following  |  22 Posts  |  Joined: 22.08.2023  |  1.7581

Latest posts by brianscience.bsky.social on Bluesky


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❤️

30.01.2026 19:57 — 👍 28058    🔁 9226    💬 362    📌 762
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Family of Alex Pretti retains lawyers who helped prosecute the George Floyd case The parents of Alex Pretti have retained a former federal prosecutor who helped Minnesota’s attorney general convict the police officer who kneeled on George Floyd’s neck of murder.

The parents of Alex Pretti have retained a former federal prosecutor who helped Minnesota's attorney general convict the police officer who kneeled on George Floyd's neck of murder. https://to.pbs.org/3ZA2HfU

29.01.2026 00:44 — 👍 24611    🔁 5572    💬 450    📌 312
Statement from Michael and Susan Pretti
Parents of Alex Jeffrey Pretti

“We are heartbroken but also very angry.

Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately, he will not be with us to see his impact.

I do not throw around the ‘hero’ term lightly. However, his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump’s murdering and cowardly ICE thugs. He had his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down, all while being pepper sprayed. 

Please get the truth out about our son. He was a good man. Thank you.

Statement from Michael and Susan Pretti Parents of Alex Jeffrey Pretti “We are heartbroken but also very angry. Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately, he will not be with us to see his impact. I do not throw around the ‘hero’ term lightly. However, his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump’s murdering and cowardly ICE thugs. He had his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down, all while being pepper sprayed. Please get the truth out about our son. He was a good man. Thank you.

Kare 11 local news just read, in full, this statement from Michael and Susan Pretti, the parents of Alex Pretti.

"Please get the truth out about our son."

25.01.2026 00:43 — 👍 24949    🔁 12882    💬 200    📌 448

🥭 is the most delicate little snowflake, formed from urine

19.01.2026 16:48 — 👍 0    🔁 0    💬 0    📌 0
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ice takes out ICE again 😬 🧊

11.01.2026 20:01 — 👍 14941    🔁 3598    💬 1216    📌 742
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High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase Extrachromosomal arrays are unique chromosome-like structures created from DNA injected into the C. elegans germline. Arrays are easy to create and allow for high expression of multiple transgenes. Th...

New preprint!

It turns out you can integrate arrays with super high efficiency using PhiC31.

www.biorxiv.org/content/10.1...

13.11.2025 02:59 — 👍 20    🔁 10    💬 3    📌 0
A Coomassie gel confirming expression of AAV particles

A Coomassie gel confirming expression of AAV particles

I can report that the Takara Bio kits work nicely.

06.10.2025 18:50 — 👍 1    🔁 0    💬 0    📌 0
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21.09.2025 23:17 — 👍 0    🔁 0    💬 0    📌 0

Looking for recommendations for a AAV purification and concentration kit that does not require ultracentrifugation.
<3

11.07.2025 19:48 — 👍 0    🔁 0    💬 1    📌 0

hands off our science pls

09.06.2025 17:49 — 👍 0    🔁 0    💬 0    📌 0

We’re using synaptophysin-tdtomato as a synapse marker for glusnfr assays. Things behave as expected.

26.05.2025 13:15 — 👍 1    🔁 0    💬 0    📌 0

🚨I converted the list of terminated #NIH grants (as of 3/22) into a google sheet. I added activity codes and award jurisdictions (see tabs for grant count and $ by each). Note this HHS list likely does not include all planned/completed terminations as of this date.🚨 Please use, share and distribute!

23.03.2025 01:47 — 👍 430    🔁 273    💬 17    📌 20

These Senators are on the fence about voting NO on the CR:

Elissa Slotkin (MI)
Gary Peters (MI)
Jacky Rosen (NV)
Jeanne Shaheen (NH)
Maggie Hassan (NH)
Jon Ossoff (GA)
John Hickenlooper (CO)
Michael Bennett (CO)
Mark Kelly (AZ)
Peter Welch (VT)
Mark Warner (VA)
Time Kaine (VA)

Call (202) 224-3121

12.03.2025 16:39 — 👍 6010    🔁 3214    💬 955    📌 495

(To the tune of "Eleanor Rigby")

🎵
Barbara McClintock
Spends all her days counting genes in kernels of corncobs
(It's all transposons)
...
All these purple kernels
Where do they all come from?
🎵

21.02.2025 20:24 — 👍 56    🔁 12    💬 4    📌 0

Disappointed that GLP-1 does not stand for 'Gila Lizard Protein 1'.

10.02.2025 10:29 — 👍 0    🔁 0    💬 0    📌 0
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Berlin Wall 20250208

08.02.2025 19:04 — 👍 2    🔁 0    💬 0    📌 0

If you put the order on a credit card, do a chargeback. GOAT tried similar shenanigans with me and a wrong colorway of air max 1s.

27.01.2025 09:50 — 👍 2    🔁 0    💬 1    📌 0
A screenshot from a 1st generation Pokémon game of a battle with “SCIENTIST wants to fight!” in the caption

A screenshot from a 1st generation Pokémon game of a battle with “SCIENTIST wants to fight!” in the caption

Live footage 🧪

23.01.2025 03:30 — 👍 249    🔁 47    💬 1    📌 2
Earth Explodes

Earth Explodes

Earth Explodes
theonion.com/earth-e...

20.01.2025 23:00 — 👍 29193    🔁 3510    💬 1039    📌 580
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🤩 and it worked

11.01.2025 12:34 — 👍 1    🔁 0    💬 0    📌 0
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Late submission to fluorescence Friday. But here's a synapse that's a little cattywampus and colored to look like the UA flag.

04.01.2025 17:55 — 👍 4    🔁 0    💬 0    📌 0

2025 resolution. do a biochemistry.

31.12.2024 21:28 — 👍 2    🔁 0    💬 1    📌 0

If you look up ‘milquetoast’ in the dictionary there’s just a picture of Merrick Garland.

25.11.2024 23:32 — 👍 1    🔁 0    💬 0    📌 0
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Post a non-religious photo you think of as holy.

24.11.2024 11:30 — 👍 4    🔁 0    💬 0    📌 0

I am speculating, but for the majority of people (unfortunately) the headline is the only interaction with the article. Journalists who continue to follow the scheme of: 1. restate the lie in the title, 2. refute the lie in the body, are only successful at propagating the lie to casual readers.

23.11.2024 11:33 — 👍 1    🔁 0    💬 0    📌 0

two examples. www.nytimes.com/article/proj... www.nytimes.com/2024/11/06/u...

23.11.2024 11:25 — 👍 0    🔁 0    💬 1    📌 0

NYTimes et al. be like: TRUMP DENIES PROJECT 2025 TIES (but he's - probably - maybe - not being completely honest. How are we to know for sure?). The telegraphed despotism needed to be on the front page daily.

23.11.2024 08:51 — 👍 1    🔁 0    💬 1    📌 0
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First of many #FluorescenceFriday on Bluesky.
3D-superresolution image of cultured cortical neurons with active zones (cyan) marked along with various ion channels (yellow, magenta). 50 um field of view. 20 nm resolution. Vutara VXL @brukercorporation.bsky.social

22.11.2024 14:18 — 👍 31    🔁 2    💬 0    📌 0
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Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]

www.fiercebiotech.com/research/rep...

17.11.2024 23:55 — 👍 248    🔁 106    💬 2    📌 13
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First Bassoon images off the scope. I think it looks right?
Magenta - WF
Green - 3D-SMLM

20.11.2024 09:03 — 👍 1    🔁 0    💬 0    📌 0

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