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Prashant Bhat

@prashantbhat.bsky.social

Uncovering the functions of genome organization | M.D. @UCLA👨🏽‍⚕️| Ph.D. '23 w/ Mitch Guttman @Caltech.edu | Previously worked on #CRISPR w/ Jennifer Doudna @UCBerkeley '14

777 Followers  |  367 Following  |  1 Posts  |  Joined: 10.11.2024  |  1.4358

Latest posts by prashantbhat.bsky.social on Bluesky

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ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...

27.11.2024 04:13 — 👍 381    🔁 151    💬 9    📌 22
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Hi! I’ll be speaking at Harvard Medical School’s Department of Biomedical Informatics on December 5th about genome organization and splicing/speckles. Thank you to the organizers for the invite! Harvard/MIT/affiliate trainees can RSVP to attend with this link: forms.gle/LopwGCc8RbuC...

19.11.2024 21:06 — 👍 2    🔁 0    💬 0    📌 0

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