Nozomu Yachie

Update: now Samantha Morris is on board too!

Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026.

massivconference.com

Abstract deadline: Nov 14

Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.

Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.

www.massivconference.com

Abstract deadline: Nov 14

@carldeboer.bsky.social @nikashakiba.bsky.social @sbmeubc.bsky.social @hedtrichlab.bsky.social @sudpinglay.bsky.social @stemcellnetwork.ca ork.ca @isscr.org🙏

Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.

Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.

www.massivconference.com

Abstract deadline: Nov 14

Please RP! A 4-day synbio and tissue engineering conference #MASSIV to transform biology and medicine together.

Couldn't list all amazing speakers, so please check out this 👉https://www.massivconference.com/

Poster due is Nov 7, but will be extended.

With @stemcellnetwork.ca and JST.

ISSCR 2026 An international gathering of the brightest minds in stem cell research and regenerative medicine across disciplines. Join us for the 2026 ISSCR Annual Meeting 8-11 July 2026 in Montréal, Canada.

I am excited to be the co-chair of #ISSCR2026 with Fiona Doetsch (mostly helping Fiona) and welcome the stem cell community in Montreal! Register to join us in Montréal, Canada on 8-11 July 2026! www.isscr2026.org

ISSCR 2026 An international gathering of the brightest minds in stem cell research and regenerative medicine across disciplines. Join us for the 2026 ISSCR Annual Meeting 8-11 July 2026 in Montréal, Canada.

I am excited to be the co-chair of hashtag#ISSCR2026 with Fiona Doetsch (mostly helping Fiona) and welcome the stem cell community in Montreal! Register to join us in Montréal, Canada on 8-11 July 2026! www.isscr2026.org

Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis - Nature Biotechnology Transcriptome-scale maps of RNA secondary structure ensembles in living cells detect candidate RNA structural switches.

Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis go.nature.com/4lLtIX8

Photos from a life sciences roundtable on June 4 with BC Premier David Eby @davidebybc.bsky.social at #CanadaPavilion of #Expo2025Osaka. Manu Madhav, Gail Murphy, and I joined from UBC. @sbmeubc.bsky.social

speakers — ISSCR 2026

#ISSCR2026 @isscr.org plenary and invited speakers have revealed! Please plan to submit an abstract and join us in Montreal! www.isscr2026.org/speakers

CAGT was fun! Thanks @carldeboer.bsky.social @sudpinglay.bsky.social and the de Boer lab for organizing! Folks from Seattle, Oregon, and other places. Great community. Arman gave a usual super talk, and Sanchit and Dayag won poster prizes☺️

Phage DisCo: targeted discovery of bacteriophages by co-culture | mSystems In this work, we describe a targeted phage discovery method that allows immediate isolation of phages with specific traits. Currently, to find a phage with specific properties, huge libraries of phage...

The latest work from my lab, Phage Disco, a method
@ellie-rand.bsky.social
developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems
journals.asm.org/doi/10.1128/...

Back to the Future with the Yachie Lab  - UBC - SBME Yachie Lab unveils a time-reversing system that allows scientists to isolate cell clones destined for important future roles  Congratulations to Drs. Nozomu Yachie and Soh Ishiguro on their recent pub...

🏎️⬅️🔥 bme.ubc.ca/back-to-the-...

oh no it's you! The person perhaps likes Chrome Hearts?

Thanks! But hold on, I think I know you, MadScientist, from the Twitter era, but who are you? lol

Haha thanks - we need to convince CIHR more :)

+Humbled by how beautifully this animated version of this week’s @nature.com cover captures two major themes of our paper – mycorrhizal fungi and the ‘wave nature of life’.

Thanks Troy! We should do something together!

Thanks Andy!

A multi-kingdom genetic barcoding system for precise clone isolation - Nature Biotechnology A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.

A multi-kingdom genetic barcoding system for precise clone isolation - @nzmyachie.bsky.social go.nature.com/4ksLOMD

A multi-kingdom genetic barcoding system for precise clone isolation - Nature Biotechnology A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.

CloneSelect published in Nature Biotechnology
@natbiotech.nature.com. This retrospective clone isolation method using CRISPR base editors is a powerful tool in broad biology. A history of Soh in the Yachie lab. www.nature.com/articles/s41...

Please plan to join us in Montréal🇨🇦 Excited to co-chair the program committee of #ISSCR2026 with @doetschlab.bsky.social. We have reorganized the concurrent themes. An exciting lineup of invited speakers will be announced soon.

Spring 2025 in UBC

I’m excited to share that we will be hosting Justin English @sbmeubc.bsky.social this Friday! Many cool synthetic biology and high-throughput screening stories are happening in his lab. His talk will be at the Life Science Institute building LSC 1002 from 11 am. Please come join us!

The 54th Naito Conference/Call for Posters The 54th Naito Conference,Call for Posters

confit.atlas.jp/guide/event/...

Poster submission is open now!👋 We are organizing the 54th Naito Conference on Genome Editing. Gorgeous speakers, including Feng Zhang, Patrick Hsu, @leopoldparts.bsky.social, Silvana Konermann, Mike Bassik, Ailong Ke, Wenning Qin, Henry Kim, Caixia Gao, Pietro Genovese, and Virginijus Siksnys.

Detecting and avoiding homology-based data leakage in genome-trained sequence models Models that predict function from DNA sequence have become critical tools in deciphering the roles of genomic sequences and genetic variation within them. However, traditional approaches for dividing ...

Special thanks to @nzmyachie.bsky.social and Brett Kiyota for this great collab! Preprint: www.biorxiv.org/content/10.1...

Hold out the genome: a roadmap to solving the cis-regulatory code - Nature A roadmap towards solving the cis-regulatory code using a combination of machine learning and massively parallel assays of exogenous DNA is proposed.

My research aims to make so much synthetic gene regulatory data that we no longer need to train models on genomic sequences (elaborated on here www.nature.com/articles/s41...), but we still lack the needed synthetic data. hashFrag is the stopgap needed to enable genome-training without leakage.

New (and hotly anticipated - at least by me) preprint from my group describing a better way to partition training data for genomic-trained models to solve the long-neglected problem of homology-based data leakage. Thread from first author @muntakimrafi.bsky.social 👇

Similarly, are we tiny fragments of time and space within the universe, or are we encompassing something else entirely?