Cyril Seillet, PhD's Avatar

Cyril Seillet, PhD

@seilletlab.bsky.social

Immunologist, NHMRC Fellow & Lab Head, Integrated Mucosal Immunity Lab @MonashUni

33 Followers  |  35 Following  |  3 Posts  |  Joined: 19.05.2025  |  1.598

Latest posts by seilletlab.bsky.social on Bluesky

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Senior Research Officer Job Title Senior Research Officer Job Description An exciting opportunity exists for a talented and commercially focused researcher with a strong interest in immunology to join the Putoczki Laboratory...

We're looking for a post-doc to join our team
@wehi-research.bsky.social

The project is fast paced and challenging, but its going to be a ton of fun!

Apply now and please spread the word

wehi.wd3.myworkdayjobs.com/broadbean_ex....

06.06.2025 05:32 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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RORΞ³t is crucial for gut homeostasis by regulating the expression of HB-EGF rather than IL-22 in activated ILC3s Li et al. show that RORΞ³t, the ILC3 master regulator, still plays a crucial role during the ILC3 activation phase. Although it is dispensable for ILC3 maintenance and their IL-22 production, it is req...

Interesting approach from Chao Zhong’s group to dissect the role of RORgt in activated ILC3 highlighting its essential function in driving HB-EGF expression, rather than IL-22.

www.cell.com/cell-reports...

06.06.2025 07:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The gut microbiome connects nutrition and human health Nature Reviews Gastroenterology & Hepatology - In this Review, Sanz and colleagues discuss how diet shapes the gut microbiome, the role of diet–microbiome interactions on the immune,...

Thrilled to share our latest review on how the gut microbiome connects diet to health, now published in Nature Reviews Gastro & Hepa! Honored to co-sign this piece with outstanding PIs @eranelinav.bsky.social @jfcryan.bsky.social Yolanda Sanz MΓ©lanie Deschasaux Rebekka Lambrecht rdcu.be/epret

04.06.2025 19:56 β€” πŸ‘ 33    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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RORΞ³t+ antigen-presenting cells mediate food tolerance - Nature Reviews Immunology Five recent papers identify the RORΞ³t+ antigen-presenting cells that induce food-antigen-specific regulatory T cells and establish food tolerance.

Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens
#oraltolerance #immunosky #foodallergy

29.05.2025 15:46 β€” πŸ‘ 28    πŸ” 13    πŸ’¬ 2    πŸ“Œ 3
Understanding the neuroimmune regulation of innate immunity | Supervisor Connect

πŸŽ“ PhD positions available @MonashUni
Join our lab to explore how neurons and immune cells shape gut immunity!
🧬 Single-cell RNAseq
πŸ”¬ 3D imaging
🧠 Neuro-immune interactions
πŸ‘₯ Great mentoring & collaborations

Apply now πŸ‘‰ tinyurl.com/Seilletlab

02.06.2025 06:59 β€” πŸ‘ 8    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social

08.05.2025 23:31 β€” πŸ‘ 31    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

Excited to see our work published on @cp-immunity.bsky.social.
Also shared by a nice commentary. really like the last sentence:
β€œNot all fuel nourishes; some, once ignited, may burn beyond control.”

18.05.2025 22:53 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.

15.04.2025 01:25 β€” πŸ‘ 14    πŸ” 9    πŸ’¬ 1    πŸ“Œ 3
Innate lymphoid cells 3 (ILC3s) are a subset of immune cells that are critical to gut immunity.β€―When there is excess fat, such as after a rich meal, ILC3s store this fat in tiny lipid droplets to maintain their function. In this 3D illustration, we can see a lipid droplet (in orange) inside an ILC3.

Innate lymphoid cells 3 (ILC3s) are a subset of immune cells that are critical to gut immunity.β€―When there is excess fat, such as after a rich meal, ILC3s store this fat in tiny lipid droplets to maintain their function. In this 3D illustration, we can see a lipid droplet (in orange) inside an ILC3.

A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.

Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.

www.wehi.edu.au/news/fast-fo...

19.05.2025 01:41 β€” πŸ‘ 9    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1

πŸ§ πŸ” Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s!
Proud to see this featured by
@wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!

19.05.2025 03:45 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

@seilletlab is following 20 prominent accounts