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Nils Norlin

@nilsnorlin.bsky.social

Exploring the life sciences with microscopy and AI Looking for postdocs to join the lab !

27 Followers  |  42 Following  |  2 Posts  |  Joined: 18.11.2024  |  1.4183

Latest posts by nilsnorlin.bsky.social on Bluesky

screenshots of some of the sample implementations

screenshots of some of the sample implementations

Screenshot of smartmicroscopy.github.io/implementations.html, showing an overview of collected implementation examples

Screenshot of smartmicroscopy.github.io/implementations.html, showing an overview of collected implementation examples

Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...

More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...

01.10.2025 09:43 — 👍 21    🔁 8    💬 1    📌 0
Post image

A new Perspective discusses the challenges of sharing annotated image datasets and offers advice for improving bioimage annotation and reuse, particularly for AI applications.

www.nature.com/articles/s41...

17.09.2025 14:56 — 👍 8    🔁 4    💬 0    📌 0
Post image

🎉 Our paper “MIFA: Metadata, Incentives, Formats and Accessibility guidelines to improve the reuse of AI datasets for bioimage analysis” is out in @natmethods.nature.com!
Community-driven standards to make bioimage data AI-ready & reusable.
👉 www.nature.com/articles/s41... #AI #Bioimaging #FAIRdata

15.09.2025 09:57 — 👍 16    🔁 8    💬 1    📌 1
Figure legend: Categories and capabilities of smart microscopy systems integrating real-time image analysis and feedback control. Top: Smart microscopy workflows can be classified based on the driving logic behind decision-making: Event-driven (reacting to rare biological events), Outcome-driven (using feedback-control to steer biological systems toward a desired state), Quality-driven (optimizing signal quality or imaging metrics), and Information-driven (guided by models that predict which measurements/perturbations will yield the most informative data). Middle: Central feedback loop between the microscope and an image analysis system, which continuously exchanges images and commands to guide acquisition dynamically. Bottom: Key control actions enabled by smart microscopy: adjusting imaging modality (e.g. switching from brightfield to fluorescence, adjusting sampling rate), repositioning the field of view (e.g. tracking, drift correction), optimizing acquisition settings (e.g. adaptive optics), and performing photomanipulation (e.g. FRAP, ablation, optogenetics).

Figure legend: Categories and capabilities of smart microscopy systems integrating real-time image analysis and feedback control. Top: Smart microscopy workflows can be classified based on the driving logic behind decision-making: Event-driven (reacting to rare biological events), Outcome-driven (using feedback-control to steer biological systems toward a desired state), Quality-driven (optimizing signal quality or imaging metrics), and Information-driven (guided by models that predict which measurements/perturbations will yield the most informative data). Middle: Central feedback loop between the microscope and an image analysis system, which continuously exchanges images and commands to guide acquisition dynamically. Bottom: Key control actions enabled by smart microscopy: adjusting imaging modality (e.g. switching from brightfield to fluorescence, adjusting sampling rate), repositioning the field of view (e.g. tracking, drift correction), optimizing acquisition settings (e.g. adaptive optics), and performing photomanipulation (e.g. FRAP, ablation, optogenetics).

🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:

21.08.2025 14:21 — 👍 36    🔁 23    💬 2    📌 1

Also, in another project we are looking for a postdoc interested in spatial omics method development and applications in cell and tissue biology. Ideally suited for someone with prior hands-on experience with MERFISH and/or ISS.

For more information or to apply, please reach out via email

11.09.2025 20:04 — 👍 1    🔁 0    💬 0    📌 0

Norlin Lab is expanding!

Postdoctoral scholarship available:

Computational microscopy with applications in lensless imaging.

Preferably, you have already developed applications using ML/AI in microscopy, though this is not strictly required.

11.09.2025 20:04 — 👍 1    🔁 0    💬 1    📌 0

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