This one is a bit of a departure from the usual and definitely a work in progress!
We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.
Read on for details... 1/x
13.09.2025 00:04 — 👍 258 🔁 81 💬 18 📌 12
Ion channels, biophysics, chemical biology, protein engineering and molecular neuroscience; Professor at University of Copenhagen; www.theplesslab.com
Research Assistant Professor at OHSU.
Structure biology| Drug resistance| Transporter| Cryo-EM| Membrane proteins|Microbiology|
Past: #UCSF, Research Specialist II | Bio5 postdoctoral fellow @uaarizona | #ICGEB #JNU #MSU
Assistant Professor at Oregon Health & Science University (OHSU) | Structural Biology | Membrane proteins | Organelle structure and function | Fatty-acid metabolism | Former postdoc- Stroud lab, UCSF | https://www.mguptalab.com | #NewPI
Scientist BRIC-THSTI, India, former post-doc Columbia University, NY, structural biology, cryo-EM, Small-angle Xray scattering, ATPases, bioenergetics
Interested in Structural Biology, deep learning, NextFlow, HPC, viruses, missense mutations archaea, bacteria, evolution & random quirks of nature. (Protein Cosmos feed 🧶🧬) Leads a research group & Structural biology Facility,UNSW Sydney. Opinions my own.
Algorithms, Software and Systems for Cryo-EM. Makers of CryoSPARC.
Cryo-EM scientist at @Sanofi Pasteur
Full Prof @BZH, Heidelberg Uni 🇩🇪, before in 🇳🇱 and🇨🇭, orig. from🇵🇹| #FirstGen, Passion for #MembraneProteins, #cryoEM, #StructuralBiology, #Biochemistry. Mentor & Mother | she/her
👉🏼 www.paulinolab.com
CryoEM, membrane proteins and whatnot
Consortium formed by Harvard Medical School, Dana-Farber Cancer Institute, Boston Children’s Hospital, and Massachusetts General Hospital.
cryoem.hms.harvard.edu
Senior Editor at a structural/molecular biology journal (NSMB).
Interested in structural biology, cryo-EM, proteins of all shapes and sizes.
Views my own.
she/her
Biochemistry 🩸 with a sprinkle of cryoEM. Not sure about my millennial status
www.valleselab.com
Scientist, 2017 Chemistry Nobel Prize (math and computational methods underlying cryo-EM of biological molecules), fiction writer, photographer, gardener.
Climate change, science education, fight of fascism
franxfiction.com and joachimfranklab.org
a senior scientist and manager at the New York Structural Biology Center, SEMC & NCCAT - https://nccat.nysbc.org - Views are my own, Reposts/Likes do not imply endorsement.
Scientist interested in structural biology, vaccine design, antibodies, protein engineering… pretty much everything
PhD student studying TRP channels by cryo-EM at Sobolevsky lab @sobolevsky.bsky.social
Structural biologist, professor, NYU School of Medicine. Alum of: Skirball Institute, EMBL, Univ Stockholm, Acad Sin, NEU. Personal account. https://scholar.google.com/citations?user=lX2sB0sAAAAJ&hl=en
Structural neurobiology lab @Cold Spring Harbor Laboratory. Cryo-EM, X-ray crystallography, Electrophysiology, Membrane protein biochemistry, Molecular neuroscience, Neuroimmunology. https://furukawalab.labsites.cshl.edu/
I am a neuroscientist at Johns hopkins University interested in the molecular mechanisms underlying learning and memory in health and disease.
Glutamate
ORCID: 0000-0001-6062-0832
