Umut Gerlevik's Avatar

Umut Gerlevik

@ugerl.bsky.social

Circadian | Chromatin | RNA @Furger Lab, Department of Biochemistry, University of Oxford

31 Followers  |  128 Following  |  4 Posts  |  Joined: 30.08.2025  |  2.4647

Latest posts by ugerl.bsky.social on Bluesky

Great to hear that, thank you!

27.10.2025 13:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ™Œ Developed with Philipp Lorenz & Anna Lamstaes, continued under Jane Mellor’s guidance.
πŸ’¬ Submitted for peer review – feedback welcome!
#SNUSeq #4sUSeq #chromatinbiology #OpenScience

24.10.2025 18:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ” What’s new?
β€’ Base-pair mapping of nascent RNA at promoters, gene bodies & enhancers
β€’ Thousands of divergently transcribed enhancers
β€’ ATAC-Seq + ChIPmentation reveal poised chromatin ready for rapid activation
#nascenttranscription #epigenomics

24.10.2025 18:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
Single Nucleotide Resolution 4sU Sequencing (SNU-Seq) reveals the transcriptional responsiveness of an epigenetically primed human genome Genomes are pervasively transcribed, leading to stable and unstable transcripts that influence 3-dimensional genome organisation and gene regulation. High sensitivity and nucleotide resolution are req...

🧬 New preprint!
SNU-Seq maps nascent transcription at single-nucleotide resolution using 4sU labeling.
Together with sf4sU-Seq, it shows how epigenetically primed chromatin rapidly activates transcription after IFN-Ξ³.
πŸ“„ doi.org/10.1101/2021...
#SNUSeq #RNAseq

24.10.2025 18:34 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 2    πŸ“Œ 0

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