Kota Saito's Avatar

Kota Saito

@saitolab.bsky.social

Akita University, Graduate School of Medicine Cell Biology, ER exit site, Secretion, Collagen

25 Followers  |  40 Following  |  2 Posts  |  Joined: 20.06.2025  |  1.5386

Latest posts by saitolab.bsky.social on Bluesky

Check out this new Roadmap, a fantastic team effort by a consortium of ER researchers. Glad we could provide the space for this synthesis, which came out of discussions at a fruitful meeting, see below:

30.09.2025 07:35 — 👍 12    🔁 8    💬 0    📌 0
Preview
Towards a unified framework for the function of endoplasmic reticulum exit sites Nature Reviews Molecular Cell Biology, Published online: 29 September 2025; doi:10.1038/s41580-025-00899-0Endoplasmic reticulum exit sites (ERES) are specialized ER subdomains that regulate the export of secreted cargo. This Roadmap explores how ERES integrate biochemical and mechanical signals to coordinate trafficking and proposes a multidisciplinary strategy to investigate their function, including in disease.

New Online! Towards a unified framework for the function of endoplasmic reticulum exit sites

29.09.2025 18:31 — 👍 13    🔁 6    💬 0    📌 1
Saito Lab|Akita University Department of Biological Informatics and Experimental Therapeutics Graduate School of Medicine, Akita University 秋田大学 大学院医学系研究科 情報制御学・実験治療学講座(旧薬理学講座)

Our lab website has been updated!  ksaitolab.com

31.07.2025 01:44 — 👍 1    🔁 0    💬 0    📌 0

Phosphorylation-Coupled Autoregulation Maintains Functional ER Exit Sites https://www.biorxiv.org/content/10.1101/2025.06.18.660491v1

20.06.2025 10:30 — 👍 2    🔁 1    💬 0    📌 0
Post image

This is my first post. We are very happy to share the following preprint!

Our work introduces a novel concept that the functional state of the ERES is maintained through the autoregulated phosphorylation–dephosphorylation cycle of key scaffold proteins.

www.biorxiv.org/content/10.1...

20.06.2025 21:22 — 👍 6    🔁 3    💬 0    📌 0

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