YouTube video by Audiommunity Episode 48 - The tyranny f the FACS machine

In the latest episode, we're talking neonatal Tregs! What are they? Still don't know! What do they do? Still don't know! Where do they go? Ahh, the right question - it's the skin of course!

With special guest @zackhilt.bsky.social 🧪 #immunology

The Tyranny of the FACS machine In this episode Matt and Kevin welcome special guest Zach Hilt from the University of Toledo - we're talking neonatal Tregs!

I recently recorded an Immunology Podcast called @audiommunity.org where I get to geek out on why Neonatal T cells are unique from Adult T cells. Please give them a listen and get the viewership up. Extra important to amplify the voice of real scientist and dampen all of the pseudoscience grifters.

YouTube video by Audiommunity Episode 47 - When you're a hammer

In our latest episode, @woodrufflab.bsky.social and @kevinbonham.com talk about glycoRNAs, and the way they're shielded from the immune system in a new paper from the labs of @raflynn5.bsky.social and @vijayrathinam.bsky.social 🧪

audiommunity.org/episodes/epi...

YouTube video by Audiommunity Episode 47 - When you're a hammer

Did you know that there are small RNAs embedded in the plasma membrane of your cells? I didn't!

But your immune system sure does! New episode of @audiommunity.org out now! 🧪

audiommunity.org/episodes/epi...

YouTube video by Audiommunity Episode 46 - Walk farther and farther to the left

The latest @audiommunity.org - Remembering David Baltimore by trying (and mostly failing) to explain the complex molecular biology in a classic #immunology paper describing the discovery of the VDJ recombinase gene 🧪

audiommunity.org/episode046

Episode 45 - Big if true | Audiommunity Get more from Audiommunity on Patreon

Oops! Forgot to post to Patreon for the last episode... #AI and #science - what's not to love? With @kevinbonham.com and @woodrufflab.bsky.social 🧪

Turns out, quite a lot

www.patreon.com/posts/episod...

Episode 45 - Big if true audiommunity.org/episodes/epi...

Someone made an AI-based "virtual lab" to engineer nanobodies - is this a paradigm shift in how we do science,
or a transpararent and cynical effort to slurp up all of the citations for being first?

In a couple of hours, @woodrufflab.bsky.social and @kevinbonham.com are going to discuss a new paper (in early preview) about an #LLM -based "virtual lab" that designed nanobodies for #sars-cov2

What would you want to know? Do you think this is a cool idea or harbinger of doom? 🧪

RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’ HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.

1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."

It's literally a vital feature of both science and of representative democracy.

I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.

Evolution - it's a hell of a drug Bacteria have immune systems? Even adaptive immune systems? And autoimmunity? Well... sort of

We decided to review this paper on the latest episode of audiommunity - check it out! audiommunity.org/episodes/epi...

Evolution - it's a hell of a drug Bacteria have immune systems? Even adaptive immune systems? And autoimmunity? Well... sort of

Bacteria have immune systems? And autoimmunity? Well...

In this episode, Kate and @kevinbonham.com discuss a new paper showing that anti-phage defenses of bacteria can provide really broad protection, but pesky selection gets in the way 🦠 🧫 🧪

audiommunity.org/episodes/epi...

Oxidized phospholipid damage signals as modulators of immunity | Open Biology Damage-associated molecular patterns (DAMPs) are self-derived molecules released during tissue damage that influence immune responses. Phospholipids, essential to cell membranes and lung surfactants, ...

Everything you wanted to know about oxidized lipids & immunity, in one review. We explain how oxidized lipids impact inflammation, dendritic cells, anti-tumor immunity and more.
Kudos to Joon Choi for his exceptional work.
royalsocietypublishing.org/doi/10.1098/...

Expression level of anti-phage defence systems controls a trade-off between protection range and autoimmunity - Nature Microbiology The authors examine several defense systems and find that increased expression enhances their protection range, albeit at a cost of autoimmunity.

Expression level of anti-phage defence systems controls a trade-off between protection range and autoimmunity
By Nitzan Aframian and Avigdor Eldar.
www.nature.com/articles/s41...

A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway Key actors of mammalian immunity originated from bacterial antiphage systems. The full extent of immune system conservation between bacteria and eukaryotes is unknown. Here, we show that the silent in...

Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...

YouTube video by Audiommunity Episode 43 - Why don't you go stain a brain?

New bluesky account, revamped website, and a new episode to boot!

@kevinbonham.com and @woodrufflab.bsky.social discuss a new paper about T cells in the subfornical organ... Why does that sound so unseemly?

audiommunity.org/episodes/epi...

youtu.be/st_g9eloJOw?...