Kamyar Hadian

Congrats James! 🎉🥂

📢 Our August issue is online!

🎨 The cover highlights a Feature Review from Stephanie Rosswag de Souza, @gzaffagnini.bsky.social, and @bokelab.bsky.social on how proteostasis functions in cellular dormancy across a number of examples, from yeast to adult quiescent stem cells and vertebrate oocytes.

Don't miss out on other great Review content!
📝 A Review from @angelifriedmann.bsky.social, @k-hadian.bsky.social, et al details the metabolic code of ferroptosis
📝 @damelab.bsky.social et al describe how prokaryotes and viruses possess histone-mediated chromatin organization

(1/n)

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance Membrane protection against oxidative insults is achieved by the concerted action of glutathione peroxidase 4 (GPX4) and endogenous lipophilic antioxidants such as ubiquinone and vitamin E. Deficienci...

🚨Preprint alert 🚨

We identify riboflavin (vitamin B₂) as a key modulator of ferroptosis sensitivity via stabilizing FSP1 & recycling lipid-soluble antioxidants.

www.biorxiv.org/content/10.1....

pls check @olzmannlab.bsky.social

www.biorxiv.org/content/10.1...

#ferroptosis #FSP1 #antioxidants

Fantastic lab with exciting science!
Strong recommendation.
Apply 👇🏻

A new postdoc position in our group will open early next year — looking for candidates with a proven track record & relevant experience.

If #CRISPRscreens, #syntheticlethality, #smallmolecules & #celldeath excite you, let’s talk! DMs welcome.

pls share 🙏

Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social

Fellowships Job: Postdoctoral Research Fellow - Jones Lab Chemistry at Dana-Farber Cancer Institute in 450 Brookline Ave, Boston, MA Postdoctoral Research Fellow - Jones Lab Chemistry job

We're hiring postdoctorate fellows in covalent chemical biology - pass the word. careers.dana-farber.org/job/11940/po...
careers.dana-farber.org/job/11941/po...

Online now - the Review "The metabolic code of #ferroptosis: nutritional regulators of cell death" from @angelifriedmann.bsky.social @k-hadian.bsky.social and colleagues.

#LipidPeroxidation #Nutrients #Metabolites #Vitamins #Lipids

Read it here 👉 authors.elsevier.com/sd/article/S...

The metabolic code of ferroptosis: nutritional regulators of cell death Ferroptosis is a distinctive form of regulated cell death driven by iron-dependent phospholipid peroxidation. Its initiation and suppression are finel…

New review together with
@k-hadian.bsky.social group-

Have fun reading!
#ferroptosis #nutrition #celldeath

www.sciencedirect.com/science/arti...

Porträtfoto von Virologin Dr. Michelle Vincendeau vom Helmholtz Munich

Virologin Michelle Vincendeau @m-vincendeau.bsky.social hat uns ein paar Fragen zu ihrer Forschung mit #Organoiden beantwortet und beschreibt, wie sie damit den Einfluss bestimmter Viren auf die Gehirnentwicklung untersucht. 🧠
#HERVs @www.helmholtz-munich.de
👉 www.infectnet.org/web/blog-pos...

Helmholtz Munich Helmholtz Munich, is a member of the Helmholtz Association of German Research Centres

👩‍🔬 Die Münchner Virologin Dr. Michelle Vincendeau @m-vincendeau.bsky.social erforscht mit Gehirn-Organoiden die Rolle von Humanen Endogenen Retroviren ( #HERVs ) bei der Gehirnentwicklung und der Entstehung von neurodegenerativen Erkrankungen. 🧠
👉 www.helmholtz-munich.de/en/viro/rese...

ÖAW: Georg Winter Life Science Direktor des AITHYRA-Instituts Biochemiker verstärkt Akademie-Institut für KI in der Biomedizin +++ ÖAW-Präsident Faßmann: „AITHYRA schon jetzt Anziehungspunkt für exzellente Forschende“

Bei unserem neuen Life Science Institut #AITHYRA gibt es den nächsten Meilenstein: Georg Winter wird neben @mmbronstein.bsky.social Direktor. Damit ist das Führungsteam komplett. Welcome on Board, Georg! www.oeaw.ac.at/news/oeaw-ge...

So true! 😊

Kaiserschmarrn is enjoyable at any altitude and in any season

Something that qualifies as big news from my side:
I am very happy and excited to announce that I have been appointed as Life Science Director at AITHYRA, a new Research Institute for Biomedical Artificial Intelligence.

Find out more in the link and 🧵 below

lnkd.in/d_HaGuSE

ÖAW: Georg Winter Life Science Direktor des AITHYRA-Instituts Biochemiker verstärkt Akademie-Institut für KI in der Biomedizin +++ ÖAW-Präsident Faßmann: „AITHYRA schon jetzt Anziehungspunkt für exzellente Forschende“

@georgwinter.bsky.social wird neuer Life Science Direktor des #AITHYRA-Instituts 🥳 Der international ausgezeichnete Biochemiker verstärkt somit das Team rund um KI-Direktor @mmbronstein.bsky.social und Administrative Direktorin Anita Ender. Mehr dazu ⤵️
www.oeaw.ac.at/news/oeaw-ge...

Only a few days left to register. We are loving the abstracts you are submitting!

We extended the deadline on the #Chicago #ASBMB #Ferroptosis meeting! 12 short talks will be selected from the abstracts. Register for what we expect to be a great conference! www.asbmb.org/meetings-eve...

A few more days left to register!

Curious about the interplay between #apoptosis and #ferroptosis and their role in cytotoxic stress, whether induced by drugs or serum depletion? Check out our latest paper in #NatureCommunications.

rdcu.be/ebbYX

@unigraz #CellDeath #LipidMetabolism

Matthias Tschöp zum neuen Präsidenten der LMU gewählt Matthias Tschöp folgt im Oktober 2025 auf Bernd Huber, der seit 2002 an der Spitze der LMU steht.

Herzlichen Glückwunsch, Matthias Tschöp. Der derzeitige CEO des Helmholtz Zentrums München wurde heute zum neuen Präsidenten der LMU gewählt. Seine sechsjährige Amtszeit beginnt am 1. Oktober 2025. www.lmu.de/de/newsroom/...

A comprehensive spatio-cellular map of the human hypothalamus - Nature HYPOMAP integrates single-nucleus RNA sequencing and spatial transcriptomic data to create a comprehensive spatio-cellular map of the human hypothalamus.

I am excited to share our latest paper @Nature where we construct a hi-res spatial map of the human hypothalamus, the brain region central in appetite control. It is a collaboration between @IMS_MRL @Cambridge_Uni & @MPI_Metabolism
www.nature.com/articles/s41...

Look forward to welcoming all participants in Frankfurt for some exciting science, building networks and having a good time 🤗🍀

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex...
A short thread to highlight some of our findings 🧵

An atlas of transcription initiation reveals regulatory principles of gene and transposable element expression in early mammalian development Mapping transcription start sites across five mammalian species before, during, and after embryonic genome activation unveils widespread transposable element-driven transcription and co-option of evol...

Tour de force! @metorrespadilla.bsky.social & team develop Smart-seq+5′ to map TSS in single embryos with unprecedented res revealing plethora of TE-driven transcripts in 5 mammal species. Some surprisingly old & conserved. Treasure trove of new biology for yrs to come!
www.cell.com/cell/fulltex...

It is great to see #NatureReviewsDrugDiscovery highlighting our work on Hi-Q brain #organoids and their application in disease modeling and drug screening, which we recently published in #NatureCommunications.

www.nature.com/articles/d41...

@naturerevdrugdisc.bsky.social
@www.helmholtz-munich.de

Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion and drug screening - Nature Communications Human brain organoids are plagued by heterogeneity and poor reproducibility, critical parameters for reliable disease modeling and drug testing. Here, the authors report on Hi-Q organoids which solve ...

And here the link to the original publication:
www.nature.com/articles/s41...

It is great to see #NatureReviewsDrugDiscovery highlighting our work on Hi-Q brain #organoids and their application in disease modeling and drug screening, which we recently published in #NatureCommunications.

www.nature.com/articles/d41...

@naturerevdrugdisc.bsky.social
@www.helmholtz-munich.de

🥹 So true