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@gastrulomicslab.bsky.social

Based in Freiburg/Germany in the Arnold-Lab, we are enthusiastic about various aspects of gastrulation: from cell behavior during morphogenesis, signals and transcriptional control, to dynamic chromatin regulation, and even biophysics of cells & tissues

83 Followers  |  78 Following  |  3 Posts  |  Joined: 09.12.2024  |  1.6471

Latest posts by gastrulomicslab.bsky.social on Bluesky

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EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling Schröder et al. describe the molecular functions of the Tbx factor Eomes, which, together with the SWI/SNF chromatin remodeling complex, establishes enhancer accessibility at mesoderm and endoderm (ME...

Excited to share our latest paper in DevCell! We show how EOMES and the SWI/SNF complex collaborate to drive chromatin remodeling, establishing mesoderm and endoderm differentiation potential.

Read the full paper here: www.cell.com/developmenta...

13.03.2025 14:07 — 👍 3    🔁 2    💬 0    📌 0

Thanks Benoît! Haha, next time I will be jealous reading your kickass papers!

12.12.2024 13:27 — 👍 1    🔁 0    💬 0    📌 0
Preview
EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling Schröder et al. describe the molecular functions of the Tbx factor Eomes, which, together with the SWI/SNF chromatin remodeling complex, establishes enhancer accessibility at mesoderm and endoderm (ME) genes during lineage specification of pluripotent cells. Eomes enables broad ME lineage competence for gene activation that relies on additional signal-induced transcription factors.

Congrats Chiara to have your beauty paper out:
www.cell.com/developmenta...

11.12.2024 19:10 — 👍 9    🔁 1    💬 1    📌 0

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