Berkley Gryder's Avatar

Berkley Gryder

@gryderart.bsky.social

Childhood Cancer Epigenetics and Drug Discovery Assistant Prof. at Case Western Reserve University gryderlab.com

53 Followers  |  23 Following  |  4 Posts  |  Joined: 12.11.2024  |  2.2446

Latest posts by gryderart.bsky.social on Bluesky

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New paper in Nature Comms with Isaac Brownell NIAMS, identifying #repurposing treatment options for the rare Merkel Cell Carcinoma (MCC). We found Aurora kinase criticality in genetic & chemogenomic screens - wonderful collaboration @gryderart.bsky.social #NCATS

www.nature.com/articles/s41...

13.02.2025 17:25 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

spectacular work! I love this paper SO much!

10.12.2024 16:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

yes this Orlando et al paper is the one with my vote. ChIP-Rx!

01.12.2024 19:45 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Proud of my collaborator @KidCancerLab for discovering how wound healing programs promote lung metastasis!
"Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells" aacrjournals.org/clincancerre...

21.11.2024 17:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Our story in PNAS today!
(1) anti-AR molecules with new mechanism: induction of chromatin binding YET a disruption of transcription
(2) why only ~150 genes respond to AR ligands, despite the 6,000+ AR binding sites: they need 3D clustering to matter!
www.pnas.org/doi/10.1073/pnas.2406239121

19.11.2024 17:44 β€” πŸ‘ 33    πŸ” 12    πŸ’¬ 1    πŸ“Œ 2

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