Paolo Caldarelli's Avatar

Paolo Caldarelli

@caldarellip.bsky.social

Postdoctoral Scientist at Caltech. Embryo and synthetic embryo morphogenesis, microscopy, and biophysics.

479 Followers  |  1,140 Following  |  32 Posts  |  Joined: 11.11.2024  |  1.4899

Latest posts by caldarellip.bsky.social on Bluesky

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AI-based approach to dissect the variability of mouse stem cell-derived embryo models - Nature Communications Stem cell-derived embryo models offer insights into early development but suffer from variability. Here, authors used AI to classify and predict outcomes for generation of mouse stem cell-derived embr...

With great supervision from @zernickagoetz.bsky.social and Ralf Mikut and a super fun collaboration with Luca Deninger! Published on @naturecomms.bsky.social!
www.nature.com/articles/s41...

20.02.2025 06:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

We developed a platform for live imaging of nearly 1,000 post-implantation mouse embryo models (ETiXs) over four days of development. Then, we applied AI computational techniques to analyze the developmental trajectories leading to normal development. More details in the paper!

20.02.2025 06:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“ข First paper from my postdoc is out! The field of stem cell-based embryo models is flourishing. These models mimic critical stages of development, providing powerful tools to study processes difficult to dissect in natural embryos. Many approaches are being usedโ€”what was ours? ๐Ÿ‘‡

20.02.2025 06:28 โ€” ๐Ÿ‘ 7    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Hi Angelo, can you please add me? Thanks!

18.11.2024 03:53 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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๐Ÿ“ขExciting news! My PhD work, supervised by @JgrosL, has just been published in @Nature. Thanks to all the co-authors! ๐Ÿ“„In this study, we (re)explored a longstanding question in developmental biology: why, when a chick embryo is cut in half during gastrulation, each half canโ€ฆ

11.09.2024 21:52 โ€” ๐Ÿ‘ 12    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Ph.D. ceremony at @institutpasteur. Super inspiring talk from Edith Heard (@heard_lab) on career paths in science. โฌ‡๏ธ๐ŸŽคThe music played by the Ph.D./Postoc band was great! ๐ŸŽผ โฌ‡๏ธ
๐Ÿ™A huge thanks to the PPU program for supporting my Ph.D. journey.๐Ÿ™

17.12.2021 16:13 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ“ขI am delighted to share part of my Ph.D. work. I am grateful to J. Gros (@JgrosL ) and F. Corson for their supervision. I also want to thank A. Chamolly and O.A.
Prevot for their invaluable contribution, and all the lab members for their support. ๐Ÿ“ข1/5

biorxiv.org/content/10.110โ€ฆ

10.10.2021 17:30 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿฅณ๐Ÿ‡ฎ๐Ÿ‡น๐Ÿฅณ

12.07.2021 00:03 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Only one hour of waiting left. So much looking forward to it!! ๐Ÿค“ #EESMorphoG #

17.03.2021 10:45 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Inspiring lecture from Thomas Lecuit on growth and size at College de France @cdf1530 .... and it just started! Looking forward for the next lecture.....

12.11.2019 10:48 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A parisian Saturday drenched in Art, with a touch of Science as well!#59ruederivoli #Paris @BarucciGiorgia

20.10.2019 17:01 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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This is how scientists celebrate the end of a ๐ŸŒกhot week๐ŸŒก at Institute Pasteur in Paris! @cecerelab @eric_cornes @BarucciGiorgia @immunozebrafish @Pierq @carolinadevbio @institutpasteur #notonlyscience #aurevoirpedro #scienceformusicians #musicforscientists

26.07.2019 17:45 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โ€œWhoa. Itโ€™s like developmental biology, but not boring.โ€....Interesting reading!

cell.com/developmental-โ€ฆ

23.07.2019 14:16 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Electroporating some quail embryos with @arjunnarayanan from the @StephanGrill lab. @arjunnarayanan is now highly quail-ified!

10.07.2019 14:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The GRC Developmental Biology was exciting and very intense. Thanks to all the people who shared their passion for science. Hope to see you all again soon. @GordonConf @mtholyoke @edd_r_c @C_Mulas @rodrigoyoungb @J_Rodenfels

21.06.2019 13:30 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Chameleon eggs for a new project. The embryonic development of these animals is so fascinating and we know so little about it. Who know where this will end up...... ๐Ÿค”

25.01.2019 10:44 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Christmas dinner of The Cecere lab. The hell of the fun!!! ๐Ÿ˜‚ @cecerelab @eric_cornes @Pierq

14.12.2018 22:42 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Finally out!! Last paper from Gros lab. I'm happy that I helped the project. Contratulations to @ChloeMoreau21.
@CurrentBiology

cell.com/current-biologโ€ฆ

14.12.2018 14:06 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Just went to the crypt of Louis Pasteur for some inspiration. There are four angles on the ciling, three rapreset the theological virtues whereas the fourth one is SCIENCE. This makes me smile every time I go there. #institutpasteur

30.11.2018 17:24 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Best letter ever written! Wait till the end! ๐Ÿ˜

17.11.2018 14:48 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Nerdy weekend at the Paris Game Week. Cool stuff! #PGW2018

28.10.2018 17:06 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Amazing!!! ๐Ÿ˜ฒ

cell.com/cell/fulltext/โ€ฆ

12.10.2018 20:05 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Day11: The EMBO workshop is over. This was 10 days of intense science, jumping between physics and biology. A big thank to Francis Robin and Michel Labouesse for organising the workshop. Now it's time to enjoy the beautiful beaches of Corsica!!! #EMBObiosystems18

21.09.2018 13:09 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Day10: Finally some plant morphogenesis with A.Boudaoud and O.Hamant!! #EMBObiosystems18

20.09.2018 15:05 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Day8: Carl-Philipp Heisenberg and how the cells migrate. #EMBObiosystems18

19.09.2018 12:26 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Day5: Eric Wieschaus told us about physics and biology. Great lecture. Brilliant mind. Totally astonishing. Very inspiring! #EMBObiosystems18

16.09.2018 21:28 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Day3: Dostatni and Walczak told us a nice story about gradient formation in embryogenesis!
#PhysicsOfIntegretedBiologicalSystems

13.09.2018 14:26 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Day2: Talk from Aurรฉlien Roux on mambrane dynamics. So far so good! #PhysicsOfIntegratedBiologicalSystems

12.09.2018 14:49 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Great start with Jacques Prost lecture!! #PhysicsOfIntegratedBiologicalSystems

11.09.2018 22:25 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

European funders seek to end reign of paywalled journals

science.sciencemag.org/content/361/64โ€ฆ

07.09.2018 10:28 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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