Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability
Losing parental histones during DNA replication fork passage challenges differentiation competence and cell viability.
ππ¨π° ππ¨ πππ₯π₯π¬ π«ππ¦ππ¦πππ« π°π‘π¨ ππ‘ππ² ππ«π πππππ« πππ π«ππ©π₯π’ππππ’π¨π§? Our new study βDisabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viabilityβ is out in ππ€πͺπ¦π―π€π¦ ππ₯π·π’π―π€π¦π΄. Led by @lleonie.bsky.social @biranalva.bsky.social 𧡠More belowπ
19.02.2025 19:35 β π 112 π 53 π¬ 5 π 5
6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
π¨πππ£π¨π« ππ¨π ππ₯ππ«π!π¨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring π ππ‘π&π©π¨π¬πππ¨ππ¬ to join the new Center for Epigenetic Cell Memory (EpiC)Β in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
12.02.2025 14:53 β π 46 π 45 π¬ 2 π 7
I wonder if my American friends understand the acute sense of collective betrayal we are experiencing in Canada right now. It's widespread and deeply felt.
02.02.2025 13:05 β π 41 π 8 π¬ 4 π 0
ICYMI: In spring 2025 the Groth lab is leaving CPR and moving to the Danish Cancer Institute along with the Mailand, Nilsson and Krietenstein labs to establish a Center of Excellence with a focus on Epigenetic Cell Memory (EpiC) π€©
25.11.2024 12:02 β π 14 π 2 π¬ 1 π 0
The Groth lab @grothlab.bsky.social has also made the jump from X to Blueskyπ€©! Please follow us for all things related to chromatin replication, epigenetic memory and (epi)genome stability in the context of mitotic cell division! We'll start on joining some relevant starter packs!
25.11.2024 12:02 β π 44 π 7 π¬ 1 π 1
The peer-reviewed version of our paper is out! Thanks to all co-authors, editor and reviewers for the smooth process π€π
And donβt miss the chromatin haiku!
www.cell.com/molecular-ce...
12.11.2024 19:36 β π 64 π 29 π¬ 5 π 4
The single-molecule accessibility landscape of newly replicated mammalian chromatin
By developing a long-read sequencing method to simultaneously map replication status
and protein-DNA contacts in cells, Ostrowski, Yang, etΒ al. show that newly replicated
chromatin is enriched for unw...
The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics
15.11.2024 15:35 β π 208 π 75 π¬ 14 π 9
Hey there Mr. @bsky.app , Iβm so pleased to be with you.
19.11.2024 07:49 β π 3 π 0 π¬ 1 π 0
Senior editor @naturesmb.bsky.social. Views and opinions are personal.
Executive Editor/Team Leader Open Access Science Journals Sage Publishing
Opinions = mine
http://linkedin.com/in/jlovick-editor
#oncology #cancerresearch #medicine #biology #cardiology #neurology #microbiology #publichealth #healthcare #technology
I do social media workshops for scientists (Bluesky, LinkedIn, X, Reddit) and like talking #philosophy and #history when I am off duty! Ex-University Post editor in Copenhagen.
Website: https://mikeyoungacademy.dk/
Linktree: https://linktr.ee/mkeyoung
Professor of Genetics and Pediatrics, UPenn/CHOPπ§¬. https://orcid.org/0000-0003-2025-5302. Views my own. π΄σ §σ ’σ ³σ £σ ΄σ ΏπΊπΈ
Interested in DNA damage, mutations, adaptation and evolution.
PhD Candidate @usponline and @icb_usp || Cancer Biology || @Arsenal through and through || βοΈ
https://sites.google.com/icb.usp.br/samsonkosemani/home?authuser=0
Dr. Brian Strahl is a chromatin researcher at UNC Chapel Hill studying how epigenetics contributes to human biology and disease. https://strahl-lab.org
Geneticist and cell biologist at the University of Southern California | DNA repair | heterochromatin | recombination | nuclear dynamics | nuclear architecture | genome stability.
Cutting-edge research, news, commentary, and visuals from the Science family of journals. https://www.science.org
Publishing reviews and commentaries across the fields of genetics and genomics. Part of Springer Nature and Nature Portfolio.
https://www.nature.com/nrg/
News from Jennifer Doudna's lab at UC Berkeley, Innovative Genomics Institute. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only.
doudnalab.org
A Cell & Developmental Biology lab @UBC. working on the role of cell junctions in development, stem cells, tissue homeostasis.
Contributing to a better world through research into the fundamental processes of living cells, tissues and organisms. The Hubrecht Institute is a research institute of KNAW and is affiliated with the UMC Utrecht.
Studying the function of chromatin in DNA Double Strand break repair at the CBI in Toulouse
Our diverse lab at @crick.ac.uk studies mechanisms of DNA repair at breaks/forks/telomeres in health & disease | Tweets by lab members unless signed SB | Views own
We are a research lab at the Netherlands Cancer Institute. We develop and apply new genomics tools to study genome biology and gene regulation.
Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. Part of @natureportfolio.bsky.social
Repost/like=interesting/relevant, not necessarily endorsement.
We are professional DNA traffic controllers and study how transcription and replication are moving smoothly (most of the time).
We use molecular & cell biology and single-molecule approaches to study DNA replication stress and its contribution to genome instability in cancer.
Stem cell scientist interested in hematopoiesis and associated diseases. Single cell proteomics is also pretty cool.
