Epigenetics Podcast

Interesting paper from Gernot Längst & Co. They calculated nucleosome repeat length in Plasmodium falciparum, the malaria-causing parasite, and showed that it follows a smooth continuous function of time (the numbers on the X axis below are hours post-invasion) www.biorxiv.org/content/10.1...

🚀 Ordering lab supplies just got way easier in our lab.
We built a workflow (github.com/farnunglab/N...) where tapping an NFC tag on a reagent bottle automatically triggers an order request in Quartzy. No more scribbling notes or hunting for a computer. Here’s how 👇

What We Learned From 150 Episodes of the Epigenetics Podcast, An Introduction to the Series In late 2017 I pressed record on the very first episode of the Epigenetics Podcast. My goal was to speak with the field’s leading voices and uncover the stories behind their discoveries. Since then th...

In 2017 I recorded the first episode of the @epigeneticspod.bsky.social. In this article I invite you to explore highlights from 150 episodes and starting a series of Articles that summarises the key lessons I learned from those conversations. #podcast

www.activemotif.com/blog-epigene...

In the most recent episode of the Epigenetics Podcast, we talked with Mo Motamedi from the Center for Cancer Research at Massachusetts General Hospital about his work on RNA-mediated epigenetic regulation. #epigenetics #podcast #chromatin

Listen here: activemotif.com/podcasts-mo-...

In this episode of the Epigenetics Podcast, we talked with Mo Motamedi from the Center for Cancer Research at Massachusetts General Hospital about his work on RNA-mediated epigenetic regulation. #epigenetics #podcast #chromatin

Listen here: activemotif.com/podcasts-mo-...

In the most recent episode of the Epigenetics Podcast, we talked with @em6wong.bsky.social from the University of New South Wales in Sydney about her work on how evolution shapes mammalian genes. #podcast #epigenetics #chromatin

Listen here: www.activemotif.com/podcasts-emi...

In this episode of the Epigenetics Podcast, we talked with
Emily Wong from the University of New South Wales in Sydney about her work on how evolution shapes mammalian genes.

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@epigeneticspod.bsky.social #podcast #epigenetics #generegulation #UNSW

Looking forward to listening!

In this episode of the Epigenetics Podcast, we talked with @em6wong.bsky.social from the University of New South Wales in Sydney about her work on how evolution shapes mammalian genes. #podcast #epigenetics #chromatin

Listen here: www.activemotif.com/podcasts-emi...

In the most recent episode of the Epigenetics Podcast, we talked with @arnausebe.bsky.social from the @crg.eu in Barcelona about his work on chromatin evolution. #podcast #chromatin #epigenetics

Listen here: www.activemotif.com/podcasts-arn...

In this episode of the Epigenetics Podcast, we talked with @arnausebe.bsky.social from the @crg.eu in Barcelona about his work on chromatin evolution. #podcast #chromatin #epigenetics

Listen here: www.activemotif.com/podcasts-arn...

Image of Niels Mejlgaar (CEO of DNRF), Anja Groth (EpiC director) & Jesper Fisker (CEO of DCS).

We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉

In the most recent episode we talked with @magnanilab.bsky.social from @icr.ac.uk about his work on epigenetic mechanisms of drug resistance and cancer cell dormancy in breast cancer. #podcast #epigenetics #chromatin

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In this episode we talked with @magnanilab.bsky.social from @icr.ac.uk about his work on epigenetic mechanisms of drug resistance and cancer cell dormancy in breast cancer. #podcast #epigenetics #chromatin

Listen here: activemotif.com/podcasts-luc...

In the most recent episode we talked with @korblab.bsky.social from @upenn.edu about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuronal activity. #podcast #epigenetics #chromatin

Listen here: www.activemotif.com/podcasts-eri...

In this episode we talked with @korblab.bsky.social from @upenn.edu about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuronal activity. #podcast #epigenetics #chromatin

Listen here: www.activemotif.com/podcasts-eri...

calling the @nucleosomepolice.bsky.social

Chromatin Profiling: From ChIP to CUT&RUN, CUT&Tag and CUTAC (Steven Henikoff) | Epigenetics Podcast In this episode of the Epigenetics Podcast, we caught up with Steven Henikoff from the Fred Hutchinson Cancer Research Center in Seattle to talk about his work on Chromatin Profiling: From ChIP to CUT&RUN, CUT&Tag and CUTAC. In the last few years Steven Henikoff has been developing methods which profile the chromatin landscape by using enzyme tethering. The quest first started with ChEC-Seq, which improved on Uli Laemmli's method of Chromatin endogenous cleavage (ChEC) but used sequencing as a read-out rather than southern blotting. Next, Cleavage Under Targets & Release Using Nuclease (CUT&RUN) was developed by making a fusion protein of Protein A and micrococcal nuclease (MNase), making it possible to achieve antibody-targeted cleavage of chromatin fragments. And finally, Cleavage Under Targets & Tagmenation (CUT&Tag) was developed by using Transposase Tn5 instead of MNase, which adds sequencing adapters and fragments chromatin at the same time, streamlining the protocol even further. In this episode we discuss how working on centromeres set the stage for Steven Henikoff’s subsequent work, how he developed CUT&RUN and CUT&Tag, what the advantages and disadvantages of those methods are and how he developed all those experiments at home in his garage.   References Takehito Furuyama, Steven Henikoff (2009) Centromeric nucleosomes induce positive DNA supercoils (Cell) DOI: 10.1016/j.cell.2009.04.049 Kristina Krassovsky, Jorja G. Henikoff, Steven Henikoff (2012) Tripartite organization of centromeric chromatin in budding yeast (Proceedings of the National Academy of Sciences of the United States of America) DOI: 10.1073/pnas.1118898109 Jorja G. Henikoff, Jitendra Thakur, … Steven Henikoff (2015) A unique chromatin complex occupies young α-satellite arrays of human centromeres (Science Advances) DOI: 10.1126/sciadv.1400234 Epigenomics Methods: ChEC-Seq, CUT&RUN, AutoCUT&RUN, Improved CUT&RUN, CUT&Tag, Automated CUT&Tag, CUTAC, scCUT&Tag.   Related Episodes The Role of Non-Histone Proteins in Chromosome Structure and Function During Mitosis (Bill Earnshaw) Hi-C and Three-Dimensional Genome Sequencing (Erez Lieberman Aiden) In Vivo Nucleosome Structure and Dynamics (Srinivas Ramachandran)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

CUT&Tag and CUT&RUN: Redefining the Standards for Protein–DNA Mapping in Epigenetics: https://epigenetics-podcast.micro.blog/2025/07/30/cuttag-and-cutrun-redefining-the.html

In the most recent episode we talked with Dr. Joseph Ecker from the Salk Institute about his work on high-resolution genome-wide mapping technologies in Arabidopsis and the human brain. #podcast #chromatin #epigenetics

Listen here: activemotif.com/podcasts-jos...

In this episode we talked with Dr. Joseph Ecker from the Salk Institute about his work on high-resolution genome-wide mapping technologies in Arabidopsis and the human brain. #podcast #chromatin #epigenetics

Listen here: activemotif.com/podcasts-jos...

In the most recent episode we talked with @teichlab.bsky.social from @cam.ac.uk about the Human Cell Atlas. #podcast #epigenetics #chromatin #singlecell

Listen here: www.activemotif.com/podcasts-sar...

In this episode we talked with @teichlab.bsky.social from @cam.ac.uk about the Human Cell Atlas. #podcast #epigenetics #chromatin #singlecell

Listen here: www.activemotif.com/podcasts-sar...

In the most recent episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified. #chromatin #podcast #epigenetics

Listen here: activemotif.com/podcasts-azi...

In this episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified. #chromatin #podcast #epigenetics

Listen here: activemotif.com/podcasts-azi...

2/3 on the Epigenetics Podcast :)

East coast chromatin mafia
@kjarmache.bsky.social

🔎 Despite failed experiments as a student, alumnus Professor Azim Surani has spent his entire career trying to understand early mammalian development.

🔬 This year marks the 40th anniversary of his discovery of genomic imprinting — the process that tags specific genes, turning

In the most recent episode of the Epigenetics Podcast, Petra Hajkova from the @mrc-lms.bsky.social‬ discusses her research on mammalian development, focusing on DNA methylation, histone modifications and TET enzymes. #podcast #epigenetics

🎧 Listen here: activemotif.com/podcasts-pet...

In this episode of the Epigenetics Podcast, Petra Hajkova from the @mrc-lms.bsky.social‬ discusses her research on mammalian development, focusing on DNA methylation, histone modifications and TET enzymes. #podcast #epigenetics

🎧 Listen here: activemotif.com/podcasts-pet...

🎙️ Catch Ani Deshpande, PhD, in episode 151 of the @epigeneticspod.bsky.social‬‬ where he discusses his work on epigenetic regulation in #AML, and the use of #CRISPR and high throughput screens for drug discovery.

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