Seychelle Vos

My dad has one of these. Fun cars :)

Same!

Congratulations Ben!

Congratulations Jimmy!

Page A04 View the The Journal for Friday, March 7, 2025

I wrote an opinion piece for my hometown South Carolina newspaper that was published today. Support science funding for our future! Standing up for science today and always! tinyurl.com/mr3vuphr

C-terminal amides mark proteins for degradation via SCF–FBXO31 - Nature SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.

🎉Super excited to share our story on how the substrate receptor FBXO31 functions as a quality control factor by recognizing amides. This has been an amazing collaboration between Bode lab and @jcornlab.bsky.social. Special shutout goes to @matthiasmuhar.bsky.social www.nature.com/articles/s41...

The short talk abstract and scholarship deadline for the Keystone Interplay of Chromatin Architecture and Transcription Regulation is tomorrow (23 January)! Get your abstracts in to be part of a great meeting in Banff this spring. @keystonesymposia.bsky.social keysym.us/KSChromatin25

Only two days left to apply to the joint Epigenetics and Chromatin Architecture & Transcription Regulation meeting 👇 We're looking forward to seeing you in Banff!

YouTube video by KeystoneSymposia KSQA: Dr. Seychelle M. Vos (Interplay of Chromatin Architecture)

Start off the New Year on a high note and submit your abstract for @KeystoneSymp Interplay of #Chromatin Architecture and #Transcription Regulation, this March/April in Banff. Short talk abstract and scholarship deadline are only 1 week away on January 9th! tinyurl.com/txn-keystone #KSChromatin25

The structural basis for RNA slicing by human Argonaute2 Mohamed et al. report the cryoelectron microscopy structure of human AGO2 with fully paired guide RNA. Their analysis reveals the structural basis for the slicing activity that drives RNAi, showing that the slicing-competent conformation is achieved by domain movements and RNA-protein contacts distinct from those of conformational intermediates and prokaryotic homologs.

Our collaborative AGO2 work with @bartellab.bsky.social is published! Abdallah and Peter used cryo-EM and biochemistry to determine the structure of AGO2 in a slicing competent conformation with a fully paired RNA. Read more about it here: tinyurl.com/AGO2-slicing

This work would not have been possible without amazing collaborators Jimmy Ly, Luisa Welp, Dan Lu, Fabian Schulte, and Henning Urlaub. @whiteheadinstitute.bsky.social

Our paper describing a novel DNA binding mode for MORC2 is published! Congratulations to Nika Fendler on her first, first author paper. This was an epic effort and revealed many new and unpredicted functions for MORC2. You can read about it here: tinyurl.com/MORC2-DNA

The short talk abstract deadline for the Keystone Interplay of Chromatin Architecture and Transcription Regulation meeting is coming up (Jan 9). The meeting is being held jointly with the Epigenetics in Development and Disease meeting. Join us in Banff for some awesome science. #KSChromatin25