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Mattia Laffranchi

@mattia-laffranchi.bsky.social

Fixed-term researcher at University of Rome La Sapienza | Immunity, cancer, and the space in between.

58 Followers  |  158 Following  |  5 Posts  |  Joined: 12.09.2025  |  1.5466

Latest posts by mattia-laffranchi.bsky.social on Bluesky

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The phenotype and related gene expressions of macrophages in adipose tissue of T2D mice following MSCs infusion Infusion of mesenchymal stem cells (MSCs) induces polarization of M2 macrophages in adipose tissue of type 2 diabetes (T2D) mice. Studies have shown tโ€ฆ

Check out:

The phenotype and related gene expressions of macrophages in adipose tissue of T2D mice following MSCs infusion

Key point:
Mesenchymal stem cells induces an M2-like state in macrophages in adipose tissue.

www.sciencedirect.com/science/arti...
#immunology #macrophages #science #elsevier

14.10.2025 13:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
RNA velocity in situ infers gene expression dynamics using spatial transcriptomics data
YouTube video by Prof. Jean Fan RNA velocity in situ infers gene expression dynamics using spatial transcriptomics data

What is RNA velocity in situ? ChatGPT kept getting it wrong...

So I made this video explaining how RNA velocity in situ infers gene expression dynamics by distinguishing nuclear vs. cytoplasmic expression in spatial transcriptomics data: youtu.be/z9Oxf1hvum0

#AcademicSky

13.10.2025 19:09 โ€” ๐Ÿ‘ 23    ๐Ÿ” 8    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

Amazing to have our work finally out!!! ๐Ÿ˜๐Ÿคฉ๐Ÿ˜

29.09.2025 18:38 โ€” ๐Ÿ‘ 36    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Check out:

Single-cell transcriptome analysis of macrophage subpopulations contributing to chemotherapy resistance in ovarian cancer
Key points:
macrophaged increased their frequency post-chemotherapy in ovarian cancers

www.sciencedirect.com/science/arti...
#Immunology #Immunobiology #Elsevier

30.09.2025 13:11 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Still relevant in Immunology:

Natural and trained innate immunity against Mycobacterium tuberculosis
www.sciencedirect.com/science/arti...

Key points:
M. Tuberculosis and BCG vaccine creates trained immune memory via TLR7/9 signaling.

#Tubercolosis #Vaccine #Immunology #Immunobiology #Elsevier

26.09.2025 11:53 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Check out one of our latest review on Chemerin (RARRES2) and it's roles in the regulation of immune responses on Journal of Leukocyte Biology.

doi.org/10.1093/jleu...

#science #immunology #review #chemerin #immunesystem

18.09.2025 14:09 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Still relevant in Immunology:

Human macrophage polarization in vitro: Maturation and activation methods compared

Key points:
Macrophage polarization is highly dependent on environmental factors.

www.sciencedirect.com/science/arti...

#Science #Immunology #Macrophage #Immunobiology #Elsevier

15.09.2025 20:12 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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