Dave Grainger

Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group.

💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."

Institute of Developmental and Regenerative Medicine (IDRM)'s Mo Space Movember, the month formerly known as November, is a moustache growing charity event held during November each year that raises funds and awareness for men's health.

Our Institute for Desperately Regrowing Moustaches @idrm.ox.ac.uk is raising money for men’s mental health, suicide prevention, and prostate and testicular cancer awareness by growing moustaches. Please donate on our Movember page if you're able!

movember.com/t/institute-...

Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social

We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇

www.biorxiv.org/content/10.1...

Pictured: Winning entries for Wildlife Photographer of the Year 2025 South African photographer Wim van den Heever takes the main prize for his shot

BBC News - Pictured: Winning entries for Wildlife Photographer of the Year 2025 - BBC News
www.bbc.co.uk/news/article...

Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration Nature Cardiovascular Research - Lekkos et al. show that a metabolic switch toward oxidative phosphorylation is required for cardiomyocyte re-differentiation and heart regeneration after injury in...

Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration.
rdcu.be/eI1v5

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

British Photography Awards The British Photography Awards is a charity oriented photography prize open to all UK residents and British photographers the world over

Whether you're into photography or not there's something here for everyone. Some amazing shots

www.britishphotographyawards.org/2025-shortli...

Picture from the edge of a cliff looking along the coast with dark grey rocks sticking out of a turbulent aqua marine sea with lots of foam

Whew the most amazing I've ever seen the sea. Off the coast of Kerry, Ireland

Featured image with David Grainger - FocalPlane Featured image with David Grainger - News

ICYMI – Our featured image was this beautiful colour-coded depth projection of the blood endothelial cells of the mouse embryonic thymus & surrounding structures.
The image was acquired by David Grainger. Find out about David’s research⤵️
focalplane.biologists.com/2025/08/29/f...
#SciArt

Have a look at my featured image with FocalPlane. It's a thymus, I swear 🦋

“I’m not sure I want to give way to the right”

From the new Private Eye, in shops now.

High-speed mapping of whole-mouse peripheral nerves at subcellular resolution A high-speed pipeline enables whole-mouse imaging and mesoscopic analysis of peripheral nerves using transgenic, immunostaining, and viral labeling, providing an effective means to map body-wide struc...

Wow
'Here, we present a high-speed blockface volumetric imaging system with an optimized workflow of whole-body clearing, capable of imaging the entire adult mouse at micrometer resolution within 40 h.'

www.cell.com/cell/fulltex...

A woman and a man standing next to eachother in a black and white room. An optical illusion makes the woman appear twice the height of the man

Giant fiancée took me out for my nearly-birthday

Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight

Comic book style drawing of a red formula 1 car driving on a race track with green mountains in the background and orange flowers in the foreground. Written on the floor next to the F1 car is written Spa Francorchamps

Looking forward to the Spa GP this weekend. Ferrari sharing some cool artwork this week

Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphatics The lymphatic vasculature is essential for fluid homeostasis, immune regulation and possesses diverse organ-specific functions. During development, lymphatic endothelial cells (LEC) arise from multipl...

Excited to share our new collaborative preprint between @uclnews.bsky.social and @sickkidsto.bsky.social 🥳

We found that kidney lymphatic vessels, an emerging target in kidney diseases, partly arises from the same group of cells that give rise to the kidney

www.biorxiv.org/content/10.1...

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I've seen a massive influx of bot-looking accounts following me on here. Almost all only posting about US politics. Hope it doesn't drown out why I joined this platform like it did on twitter

Development presents... Wednesday 4 June 15:00 BST BSDB poster prize winners. CHair: Abigail Tucker Giulia Paci University College London - ‘3D cell topology regulates signalling range to promote precise patterning of wing sensory organs’ Shifaan Thowfeequ University of Oxford - ‘Visualising calcium dynamics in the developing embryo: from fertilisation to the first heartbeat’

Register now to attend our #DevPres webinar next week, featuring the winners of the @bsdb.bsky.social poster prize, @shifaant.bsky.social and @giuliapaci.bsky.social, and chaired by Abigail Tucker.

4 June at 15:00 BST

us02web.zoom.us/webinar/regi...

🎓 The MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) is inviting applications for a fully funded DPhil studentship, based at the IDRM.

Learn more and apply: lnkd.in/gb-mEX8K

@oxforddpag.bsky.social

My entry SMILE made it into the top ten 😁

Alongside many great entries. My favourite is Minnie's Bow!

Great evening of talks at #pint25 in Oxford Tech Me Out theme. Very interesting talks from Alex and Jorge from @alpinef1.bsky.social followed by Muhammed Waqas from JLB.

Alpine even brought a front wing from their 2024 F1 car!
@pintofscience.uk

Great weekend celebrating @emmarose64.bsky.social's graduation with friends and family. Very proud! 😊

We indeed got many entries!

✨Tickets for #pint25 are now on sale!✨
🎟Book here 👉 pintofscience.co.uk 👈
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🗓19th-21rd May 2025
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World map with YEN Image Competition contributors.

YEN Image Competition Update!

We already have some amazing contributions from early career researchers from the UK, Switzerland and US. We would love to see contributions from other countries as well! If you can't travel to the conference remember you can always participate online.

#onlywithHCR: @degrainger.bsky.social, @oliverastone.bsky.social, and their team reveal that lymphatic endothelial cells arise from specialized progenitors. #HCRimaging helped them to visualize endothelial progenitors in whole-mount mouse embryos.

Learn more: www.nature.com/articles/s44...

Lymphatic vessels traced to their origins from a specialised pool of cells called angioblasts

📷: Irina Lupu @degrainger.bsky.social Nils Kirschnick et al @oliverastone.bsky.social Friedemann Kiefer
@ox.ac.uk @uni-muenster.de @naturecvr.bsky.social

➡️: bpod.org.uk/archive/2025...

Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium - Nature Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous...

• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵

www.nature.com/articles/s41...
Laymen video:
www.nature.com/articles/d41...

Vote for your favourite image in the Node–FocalPlane image competition - the Node Browse through the gallery of the 15 shortlisted images and vote for your favourite image by Wednesday 26 March.

Together with @focalplane.bsky.social, we're having an image competition to accompany the #Biologists100 conference.

Thank you everyone who submitted their images. Shortlisting only 15 was tough!

Browse through the gallery and vote for your favourite image:
thenode.biologists.com/vote-for-you...

A vibrant abstract image with a network of lines in blue, purple, yellow, and red against a white background. Shape resembles a medical illustration of a woman with a painterly effect

Some great images in this years @the-node.bsky.social image competition. Including my own "Thymus in the Spotlight" image taken in the @idrm.ox.ac.uk Zeiss CoE.

Vote for your favorite here: thenode.biologists.com/vote-for-you...