 
                                                         
                                                
    
    
    
    
            Great flash talks from Anton Patrikeev (HPV evolution in head and neck cancer) and Florian Gabel (resistance evolution in prostate cancer) both from our @cec-icr.bsky.social @icr.ac.uk #CrickCancerConf
               
            
            
                07.10.2025 10:45 β π 9    π 1    π¬ 0    π 0                      
            
         
            
        
            
        
            
            
            
            
            
    
    
    
    
            Here's our latest - jointly with @rhaq1.bsky.social lab & co-lead by Drs. Schiantarelli, Benamar, Park et al - studying why some tumors stop responding to immunotherapy. This continues to be a tough puzzle to solve, but important for science & patients alike...
               
            
            
                10.02.2025 23:38 β π 18    π 4    π¬ 1    π 0                      
            
         
            
        
            
            
            
            
            
    
    
            
                             
                        
                Save The Prince Charles Cinema
                The iconic Prince Charles Cinema in Londonβs West End future is under serious threat!
We are beyond disappointed that our landlords Zedwell LSQ Ltd and their ultimate parent company Criterion Capital...
            
        
    
    
            #SaveThePCC
Some of you may have read about the situation regarding our new landlord wishing to add a new redevelopment break clause, with only 6 months notice to our lease.
For now, we're simply asking you all to share & sign the petition below;
you.38degrees.org.uk/p/princechar...
               
            
            
                28.01.2025 10:14 β π 2164    π 2104    π¬ 81    π 543                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Salary? Good, I bet?
               
            
            
                12.12.2024 09:57 β π 0    π 0    π¬ 0    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            It's a great book, such nice production quality.
               
            
            
                12.12.2024 09:56 β π 0    π 0    π¬ 0    π 0                      
            
         
            
        
            
            
            
            
                                                 
                                                
    
    
    
    
            PARP inhibitor, olaparib, has transformed treatment for men whose #prostatecancer has DNA repair defects, but most cancers eventually become resistant.
@seedgeorge.bsky.social at @icrlondon.bsky.social has uncovered genomic changes that predict how long men will respond.π§΅
doi.org/10.1016/j.cc...
               
            
            
                09.12.2024 16:01 β π 5    π 1    π¬ 1    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            This work was supported in part by @prostatecanceruk.bsky.social, who really are leaders in supporting research and have been fantastic to work with.
               
            
            
                05.12.2024 20:24 β π 5    π 0    π¬ 3    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Delighted that a major project of my post-doctoral fellowship in the de Bono lab has been published. A really interesting story, featuring the likes of @icrlordlab.bsky.social @boragurel.bsky.social among many others at @icrlondon.bsky.social and elsewhere.
               
            
            
                05.12.2024 20:24 β π 12    π 5    π¬ 1    π 0                      
            
         
            
        
            
            
            
            
                                                 
                                                
    
    
    
    
            This weeks coffee club paper focuses on genomic changes linked to PARP inhibitor resistance β
The work was led by @prostatecanceruk.bsky.social's Travel Prize Fellow @seedgeorge.bsky.social from @icrlondon.bsky.social
Congratulations to George and team π₯³
t.co/rC22HnAKIs
#prostatecancer #research
               
            
            
                28.11.2024 12:21 β π 12    π 3    π¬ 1    π 1                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            What a steal!
               
            
            
                28.11.2024 13:00 β π 2    π 0    π¬ 0    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            "Shock Christmas Message: Doctors say ABSENCE Makes the Heart Grow FONDER"
Health experts today warn about the risks of over-fondness and wistfulness, as growing absence rates lead to a rise in diagnoses nationwide.
               
            
            
                22.11.2024 09:47 β π 3    π 0    π¬ 0    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Don't forget to save these functions in different scripts that are all sourced at different points.
               
            
            
                20.11.2024 12:37 β π 0    π 0    π¬ 0    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            It's a challenge to strike this balance, partly because of the well-described pressures we are under to deliver "results". Your boss lets you know there will be some transcriptome data coming - how much of a deep dive can you afford to do on the methods? It's non-trivial.
               
            
            
                20.11.2024 09:50 β π 1    π 0    π¬ 0    π 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            I'd say that while frequently packages 'work' - ie. produce output without complaint - but is the output useful? Has it worked 'correctly'? It's part of the challenge of the field, really, and ties in with the thread: the user has to understand what the inputs and outputs look like. And that's hard!
               
            
            
                20.11.2024 09:40 β π 0    π 0    π¬ 0    π 0                      
            
         
    
         
        
            
        
                            
                    
                    
                                            Bioinformatician 𧬠Epigenetics, Drug Development, Translational Medicine @ The Institute of Cancer Research πCareer Londoner also
                                     
                            
                    
                    
                                            Executive Editor of Cancer Discovery, published by AACR. Harvard BBS/Dana-Farber alum. Native New Yorker. Posts are my own. She/her https://aacrjournals.org/cancerdiscovery
                                     
                            
                    
                    
                                            Medical Oncologist 
40tude sponsored Tom Smith Fellow
St Marks Research Fellow
Genomics and Evolutionary Dynamics lab ICR
Imperial PhD candidate working on adaptive immunity in Lynch syndrome
                                     
                            
                    
                    
                                            Target Evaluation & Molecular Therapeutics lab at the Institute of Cancer Research, London. Unironically passionate about target validation π― and drug discovery π in oncology.
                                     
                            
                    
                    
                                            Writer of fantasy and SF. Gardener. Chicken tender. Dog Person but cat friendly. Washington state USA. Old and getting older. Stay off my lawn! No AI ever. All posts from me.
                                     
                            
                    
                    
                                            Prof of Public Engagement in Science, Uni of Birmingham; anatomist, author, broadcaster; vice President of Humanists UK. All views my own.
                                     
                            
                    
                    
                                    
                            
                    
                    
                                            Director, Centre for Evolution and Cancer @cec-icr.bsky.social at @icr.ac.uk 
Genomics, epigenetics, evolution, mathematical modelling, data science, bowel cancer
                                     
                            
                    
                    
                                            Head of Research Impact and Engagement at Prostate Cancer UK and dog owner. Will post about opportunities for prostate cancer researchers with the occasional picture of my dog! Views are my own.
                                     
                            
                    
                    
                                    
                            
                    
                    
                                            Computational pathologist, specializing in Uropathology. AΓTF β01, HΓTF β07, JHU β11, ICR '23. Ex-DoΓ§ent. Views most definitely my own. Occasional #Formula1 posts π Clinician Scientist in the De Bono lab #pathsky #medsky
                                     
                            
                    
                    
                                            Clinical Computational Oncology @vanallenlab DFCI and @culhanelab UL. 
brendanreardon.com
                                     
                            
                    
                    
                                            Award-winning poltergeist and comedian | Writer of the Montgomery Bonbon mysteries | Pronouns like a butler coughing: he/him | linktr.ee/misterabk
UK TOUR 2026: www.mickperrin.com/tours/alasdair-beckett-king-king-of-crumbs
                                     
                            
                    
                    
                                            Deputy Director & Head of Comms at The Institute of Cancer Research, previously research comms at the BHF. All my own views. #SciComm, #PR, #Comms, #CharityComms
                                     
                            
                    
                    
                                            Musician, comedian, theoretical physicist. Ninja Brian from NSP & Starbomb, Trey Magnifique from Jazz, Brian Wecht from Leighton Night with Brian Wecht
                                     
                            
                    
                    
                                            Evolution and cancer research @icrlondon.bsky.social.
Interests include:
drug resistance
pre-malignancy and early detection
epigenetics
plasticity
population genetics
microbiome
lineage tracing
biotech
Director @trevorgraham.bsky.social
                                     
                            
                    
                    
                                            Clinical Genomics in the UK. 
Scientific Director of Clinical Genomics at the Royal Marsden and North Thames GLH. Prof of Translational Genomics at ICR, London
                                     
                            
                    
                    
                                            Author: Children of Time, Shadows of the Apt, Final Architecture, City of Last Chances and others. adriantchaikovsky.com
                                     
                            
                    
                    
                                            We make excellent TTRPGs: Eat the Reich, DIE, Heart, Spire, Hollows, Voidheart Symphony, Honey Heist, etc. Made of lovely humans; home of UFO Press. 
                                     
                            
                    
                    
                                            Menswear writer. Editor at Put This On. Words at The New York Times, The Washington Post, The Financial Times, Esquire, and Mr. Porter. 
If you have a style question, search:
https://dieworkwear.com/ | https://putthison.com/start-here/