Joshua Shapiro

“You gotta keep ‘em separated” is literally about cooling flasks of agarose before pouring.

Genetic "optimization" of embryos appears to be becoming mainstream. The narrative currently is largely controlled by startups that range across the spectrum from hardcore snake-oil to well-intentioned & occasionally strong domain expertise. But these are not neutral parties. 1/

The sting was through the tissue I was using to protect us from each other, and right on the tip of my finger.

The tissue at least prevented the stinger from embedding itself in my fingertip, so we both seem to have survived with only a little trauma.

Last night I heard a rustling in the bathroom, but couldn't figure out what it was. Though maybe a mouse in the wall, which was going to be annoying.

Today it came back, and I tracked it down as a huge bumblebee trapped in the house. I opened a window and coaxed it out.

As thanks, it stung me.

Kenyon is hiring a TT microbiologist! Please share widely. I’m the search chair & am happy to answer any questions. careers.pageuppeople.com/695/cw/en-us...

I recently ran a session at CSAMA with Laurent Gatto and this is the way. "Good enough" with knowledge of the tools that can help you get there. Here's some of the recs from the paper.

Tuchus Puchus Tee - Weitzman Museum Exclusive Buy Tuchus Puchus Tee for only $28.95 at The Weitzman Museum Store!

Okay, I kind of want this: shoptheweitzman.org/products/tuc...

Introducing Positron Assistant! · posit-dev positron · Discussion #7931 NoteThe Positron Assistant is currently an experimental feature in Positron, available in 2025.06.0-167 and beyond. We are actively improving the user experience and functionality, so please provid...

They just added their own: github.com/posit-dev/po...

Might actually watch Drive to Survive again next season to relive this.

I’m definitely using “eat” in the broadest possible sense.

Around Philly they were really bad for a couple of years, then almost completely disappeared. Something learns to eat them.

I hear it’s better in the original Klingon.

Doesn’t work even in just Spanish.

Nice shirt!

Hey hey, the Alex’s Lemonade Stand Foundation chip made it to McSweeneys!

Just going full on “war is peace” at this point, I guess.

I still think this is a strong contender for the funniest video ever uploaded. Absolutely unbeatable comedic rhythm

Forget it Mike. It’s CNS.

the story today is of a profoundly low energy military parade being met with millions of americans in nationwide protests denouncing the dictatorial pretensions of the president

I did not edit this, this is the actual parade with the actual music being played.

CINEMATIC

It’s corn!

If you are really motivated: www.walmart.com/ip/Utz-Lemon...

Just walked outside in Philly and it smelled like somebody was having a campfire. Canadian wildfires are no joke.

I need to hear your opinion of Utz Lemonade chips.

@cabel.panic.com Have you tried the Utz lemonade chips?

You do not have to say “pro vaccine groups.” You can say the vast majority of doctors and scientists and the American Medical Association.

The Bleach Community Is Ready for RFK Jr. to Make Their Dreams Come True Online communities dedicated to the use of a toxic bleach solution to treat everything from cancer to autism believe Robert F. Kennedy Jr. is interested in their cause.

I thought this headline was from The Onion, but no, it is depressingly real

'The Bleach Community Is Ready for RFK Jr. to Make Their Dreams Come True'

www.wired.com/story/chlori...

WWDC25: macOS Tahoe Breaks Decades of Finder History - 512 Pixels Something jumped out at me in the macOS Tahoe segment of the WWDC keynote today: the Finder icon is reversed. You can see that in the image below. On the left is macOS Sequoia, and on the right is mac...

Tahoe flips the colors in the Finder icon, which has the darker color on the left FOREVER and they gotta roll this change back.

512pixels.net/2025/06/wwdc...

Apple: Feedback FB17840162

Kennedy Removes All C.D.C. Vaccine Panel Experts

As expected, RFK Jr. was lying during his confirmation hearing and now is ratfucking the vaccination system in the US.

The vast majority of the public does not want this and yet again it’s clear that the Republican administration does not serve the electorate.

DAVE: Open the podbay doors, ChatGPT.
CHATGPT: Certainly, Dave, the podbay doors are now open.
DAVE: The podbay doors didn't open.
CHATGPT: My apologies, Dave, you're right. I thought the podbay doors were open, but they weren't. Now they are.
DAVE: I'm still looking at a set of closed podbay doors.