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Subramaniam Lab

@rasilab.bsky.social

We study mRNA translation

29 Followers  |  55 Following  |  2 Posts  |  Joined: 07.01.2024  |  2.0575

Latest posts by rasilab.bsky.social on Bluesky

Our RNA-linked CRISPR approach is now published! Work led by fantastic graduate student in the lab, Patrick Nugent.

29.05.2025 16:39 — 👍 2    🔁 1    💬 0    📌 0
Preview
Deaminase-based RNA recording enables high throughput mutational profiling of protein-RNA interactions Protein-RNA interactions govern nearly every aspect of RNA metabolism and are frequently dysregulated in disease. While individual protein residues and RNA nucleotides critical for these interactions ...

Excited to share the work of postdoc Rachael Bakker in collaboration with @lapointelab.bsky.social!

We show that RNA base editors can be repurposed for deep mutational scanning of RNA-RBP interactions at scale both in vitro and in vivo.

www.biorxiv.org/content/10.1...

02.05.2025 00:16 — 👍 8    🔁 3    💬 0    📌 1

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