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@mvstaller.bsky.social

131 Followers  |  94 Following  |  2 Posts  |  Joined: 05.12.2024  |  1.5141

Latest posts by mvstaller.bsky.social on Bluesky

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Short activation domains control chromatin association of transcription factors Transcription factors regulate gene expression with DNA-binding domains (DBDs) and activation domains. It is generally assumed that DBDs are solely responsible for interacting with DNA and chromatin. ...

Happy new year! Our new preprint is live! We use single molecule imaging in live cells to show that activation domains can control how transcription factors bind to chromatin. SMT 1 TF Dogma 0 www.biorxiv.org/content/10.1...

10.01.2025 17:07 — 👍 10    🔁 4    💬 0    📌 0

Our new preprint went live on biorxiv. We show: 1) conservation of function without conservation of sequence for a transcription factor over 600 million years of evolution. 2) The key​ phenylalanine residues turnover​, moving around. www.biorxiv.org/content/10.1...

10.12.2024 20:51 — 👍 34    🔁 10    💬 1    📌 1

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