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Christine Moene

@cmoene.bsky.social

PhD student at the Netherlands Cancer Institute || gene regulation - epigenetics - genome organization || she/her

34 Followers  |  32 Following  |  1 Posts  |  Joined: 19.09.2025  |  1.5008

Latest posts by cmoene.bsky.social on Bluesky

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Functional maps of a genomic locus reveal confinement of an enhancer by its target gene Genes are often activated by enhancers located at large genomic distances, and the importance of this positioning is poorly understood. By relocating promoter-reporter constructs into thousands of alt...

โœจExciting news: the main story of my PhD is out in Science!

Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genomeโ€”revealing how Sox2โ€™s position shapes enhancer activation.

๐Ÿ“– Read the full story here: www.science.org/doi/10.1126/...

19.09.2025 14:09 โ€” ๐Ÿ‘ 93    ๐Ÿ” 37    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

Have you ever wondered how the exact location of a gene affects it's activity?

The main story of my PhD deals with exactly that question, and is now published in Science! โœจ
www.science.org/doi/10.1126/...

My amazing co-author and friend @mathiaseder.bsky.social summarized the highlights for you

19.09.2025 14:22 โ€” ๐Ÿ‘ 36    ๐Ÿ” 13    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

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